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Phenotype of peripheral blood lymphocytes and serum immunoglobulin concentration in patients with early rheumatoid arthritis

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Abstract

We studied the phenotype of peripheral blood lymphocytes and serum immunoglobulin concentration in patients with early rheumatoid arthritis and rheumatoid arthritis of more than 12 months duration. Subpopulations of CDIgM+, CD25+, and HLA-DR+ lymphocytes and IgA concentration differed in these groups of patients with rheumatoid arthritis. The count of lymphocytes carrying CDIgM+ and HLA-DR+ receptors correlated with activity of rheumatoid arthritis.

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References

  1. I. R. Kolosova, E. R. Polosukhina, A. Yu. Baryshnikov, et al., Nauch.-Prakt. Revmatol., No. 3, 6–9 (2003).

  2. V. T. Timofeev, N. A. Shostak, T. K. Loginova, et al., Ter. Arkhiv, No. 5, 19–21 (2000).

  3. K. Aho, M. Heliovaara, P. Knekt, et al., Ann. Rheum. Dis., 56, 351–356 (1997).

    CAS  PubMed  Google Scholar 

  4. N. A. Artemenko and L. P. Sizyakina, Russ. J. Immunol., 3, No. 2, 167–172 (1998).

    PubMed  Google Scholar 

  5. P. Emery, F. C. Breedveld, M. Dougados, et al., Ann. Rheum. Dis., 61, 290–297 (2002).

    Article  CAS  PubMed  Google Scholar 

  6. G. S. Firestein, Nature, 423, 356–361 (2003).

    Article  CAS  PubMed  Google Scholar 

  7. G. S. Firestein, Arthritis Res. Ther., 7, 157–159 (2005).

    Article  PubMed  Google Scholar 

  8. J. J. Goronzy and C. M. Weyand, Curr. Opin. Rheumatol., 16, 212–217 (2004).

    CAS  PubMed  Google Scholar 

  9. G. Manda, M. Neagu, A. Livescu, et al., J. Cell. Mol. Med., 7, 79–88 (2003).

    PubMed  Google Scholar 

  10. K. Naylor, G. Li, A. N. Vallejo, et al., J. Immunol., 174, 7446–7452 (2005).

    CAS  PubMed  Google Scholar 

  11. M. M. Nielen, D. Van Schaardenburg, H. W. Reesink, et al., Arthritis Rheum., 50, 380–386 (2004).

    PubMed  Google Scholar 

  12. F. Ponchel, A. W. Morgan, and S. J. Bingham, Blood, 100, 4550–4556 (2002).

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. A. I. Nesterov Department of Faculty Therapy, Medical Faculty, Russian State Medical University, Russian Health Ministry, Moscow

    V. T. Timofeev, N. A. Shostak, D. A. Anichkov & A. Yu. Potanin

  2. Problem Research Laboratory of Cardiovascular Diseases, Russian State Medical University, Russian Health Ministry, Moscow

    V. T. Timofeev

Authors
  1. V. T. Timofeev
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  2. N. A. Shostak
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  3. D. A. Anichkov
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  4. A. Yu. Potanin
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Corresponding author

Correspondence to A. Yu. Potanin.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 1, pp. 92–94, January, 2006

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Timofeev, V.T., Shostak, N.A., Anichkov, D.A. et al. Phenotype of peripheral blood lymphocytes and serum immunoglobulin concentration in patients with early rheumatoid arthritis. Bull Exp Biol Med 141, 84–86 (2006). https://doi.org/10.1007/s10517-006-0100-9

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  • DOI: https://doi.org/10.1007/s10517-006-0100-9

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