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Correction of Changes in ADP-Induced Platelet Aggregation with Vasopressin Analogue Desglycinamide-Arginine-Vasopressin

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Abstract

We studied the effect of vasopressin analogue desglycinamide-arginine-vasopressin on changes in platelet hemostasis produced by intragastric administration of Ticlid or clopidogrel (inhibitors of ADP-induced platelet aggregation). Intranasal administration of the peptide under conditions of hemorrhagic diathesis produced a hemostatic effect and normalized some parameters of blood coagulation.

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REFERENCES

  1. V. P. Baluda, Z. S. Barkagan, E. D. Gol'dberg, et al., Laboratory Methods to Study the System of Hemostasis [in Russian], Tomsk (1980).

  2. Z. S. Barkagan, Hemorrhagic Diseases and Syndromes [in Russian], Moscow (1988).

  3. M. G. Golubeva, T. M. Kalishevskaya, and M. E. Grigor'eva, Dokl. Ros. Akad. Nauk, 348, No.2, 270–271 (1996).

    Google Scholar 

  4. M. G. Golubeva, T. M. Kalishevskaya, M. E. Grigor'eva, et al., Vestn. Mosk. Gos. Univ., No. 4, 3–11 (1999).

  5. N. A. Gratsianskii, O. V. Averkov, and N. N. Slavina, Use of New Antiplatelet Drugs (Ticlopidine and Clopidogrel) for Acute Coronary Syndrome without ST Segment Elevation (Instable Angina Pectoris and non-Q Wave Myocardial Infarction). Manual for Physicians [in Russian], Moscow (2001).

  6. E. V. Gubler and A. A. Genkin, Use of Nonparametric Statistical Tests in Medical and Biological Studies [in Russian], Leningrad (1973).

  7. M. E. Bertrand, H.-J. Rupprecht, P. Urban, et al., Curculation, No. 8, 624–629 (2000).

  8. D. L. Bhatt and A. T. Hirsch, Ibid., No. 1, 646 (1999).

  9. P. B. Conley and S. M. Delaney, Curr. Opin. Hematol., 10, No.5, 333–338 (2003).

    Article  PubMed  Google Scholar 

  10. C. Gachet, Thromb. Haemost., 86, 222–232 (2001).

    PubMed  Google Scholar 

  11. J. P. Herault, F. Dol, C. Gaich, et al., Ibid., 78,Suppl. 1, No. 6, 957–960 (1999).

    Google Scholar 

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Authors and Affiliations

  1. Department of Human and Animals Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Russia

    M. G. Golubeva, M. E. Grigor'eva & M. P. Smirnova

Authors
  1. M. G. Golubeva
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  2. M. E. Grigor'eva
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  3. M. P. Smirnova
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Correspondence to M. G. Golubeva.

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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 140, No. 8, pp. 127–129, August, 2005

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Golubeva, M.G., Grigor'eva, M.E. & Smirnova, M.P. Correction of Changes in ADP-Induced Platelet Aggregation with Vasopressin Analogue Desglycinamide-Arginine-Vasopressin. Bull Exp Biol Med 140, 162–164 (2005). https://doi.org/10.1007/s10517-005-0434-8

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  • DOI: https://doi.org/10.1007/s10517-005-0434-8

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