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Glutathione-S-Transferase Polymorphism and Clinical Features of Acute Drug Poisoning in Children

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Abstract

We studied the association of GSTM1 and GSTT1 and GSTP1 Ile105-Val105 polymorphism with the duration of intoxication, polyorgan failure, and severity of drug poisoning in children. The combination of GSTM1 and GSTT1 zero genotypes is a favorable sign for the duration of intoxication and severity of the disease.

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Correspondence to V. A. Vavilin.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 139, No. 4, pp. 424–427, April, 2005

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Vavilin, V.A., Safronova, O.G., Manankin, N.A. et al. Glutathione-S-Transferase Polymorphism and Clinical Features of Acute Drug Poisoning in Children. Bull Exp Biol Med 139, 431–433 (2005). https://doi.org/10.1007/s10517-005-0314-2

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  • DOI: https://doi.org/10.1007/s10517-005-0314-2

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