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Stress-Inducing Effect of Hypoxia of Different Origin and Its Correction with Inula Helenium L. Tincture

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

In order to evaluate the severity of stress, the effects of single and repeated exposure to hypoxia of different origin (hemic, tissue, and circulatory) on the classical parameters of the Selye triad, cytological characteristics of lymphoid organs, and karyometric parameters (nucleus diameters) were studied in all adrenal zones, and analysis of correlations was carried out. The corrective effect of Inula helenium L. tincture manifested in prolongation of the lifespan and normalization of somatic and morphological parameters.

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Authors and Affiliations

  1. Institute of Pharmacology, Tomsk Research Center, Siberian Division, Russian Academy of Medical Sciences, Tomsk, Russia

    K. L. Zelenskaya, T. N. Povet’eva, V. G. Pashinskii, T. N. Fomina, E. A. Timina & A. V. Perova

Authors
  1. K. L. Zelenskaya
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  2. T. N. Povet’eva
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  3. V. G. Pashinskii
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  4. T. N. Fomina
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  5. E. A. Timina
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  6. A. V. Perova
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Correspondence to K. L. Zelenskaya.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 139, No. 4, pp. 406–409, April, 2005

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Zelenskaya, K.L., Povet’eva, T.N., Pashinskii, V.G. et al. Stress-Inducing Effect of Hypoxia of Different Origin and Its Correction with Inula Helenium L. Tincture. Bull Exp Biol Med 139, 414–417 (2005). https://doi.org/10.1007/s10517-005-0309-z

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  • DOI: https://doi.org/10.1007/s10517-005-0309-z

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