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Reactivity of Rat Basilar Artery to Serotonin after Short-Term Ischemia of Hindbrain and during Chronic Vertebrobasilar Insufficiency

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Abstract

Contractile responses of the basilar artery to serotonin were examined in vitro on two models of circulation disturbances in the vertebrobasilar region of the brain. Two days after 30-min reversible occlusion of vertebral arteries, the sensitivity of the basilar artery to serotonin decreased, while chronic vertebrobasilar insufficiency had no effect on serotonin-induced contraction.

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Authors and Affiliations

  1. Fundamental Medicine Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia

    V. V. Sabadash, O. E. Fadyukova & V. B. Koshelev

Authors
  1. V. V. Sabadash
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  2. O. E. Fadyukova
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  3. V. B. Koshelev
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Correspondence to O. E. Fadyukova.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 139, No. 4, pp. 399–402, April, 2005

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Sabadash, V.V., Fadyukova, O.E. & Koshelev, V.B. Reactivity of Rat Basilar Artery to Serotonin after Short-Term Ischemia of Hindbrain and during Chronic Vertebrobasilar Insufficiency. Bull Exp Biol Med 139, 408–410 (2005). https://doi.org/10.1007/s10517-005-0307-1

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  • DOI: https://doi.org/10.1007/s10517-005-0307-1

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