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Bulletin of Experimental Biology and Medicine

, Volume 139, Issue 1, pp 141–144 | Cite as

First experience in the use of bone marrow mesenchymal stem cells for the treatment of a patient with deep skin burns

  • M. F. Rasulov
  • A. V. Vasil’chenkov
  • N. A. Onishchenko
  • M. E. Krasheninnikov
  • V. I. Kravchenko
  • T. L. Gorshenin
  • R. E. Pidtsan
  • I. V. Potapov
Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)

Abstract

Female patient with extensive skin burn (I-II-IIIAB skin burn, total area 40%, area of IIIB degree 30%) was treated using transplantation of allogenic fibroblast-like bone marrow mesenchymal stem cells onto the surface of deep thermal burn. The study of wound healing dynamics after transplantation of allogenic fibroblast-like mesenchymal stem cells confirmed high tempo of wound regeneration in the presence of active neoangiogenesis. Due to this, autodermoplasty of burn wounds could be carried out with good results as early as on day 4 after transplantation of fibroblast-like mesenchymal stem cells; this led to more rapid healing of donor zones and accelerated rehabilitation of the patient.

Key Words

bone marrow mesenchymal stem cells fibroblasts burn 

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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • M. F. Rasulov
    • 1
  • A. V. Vasil’chenkov
    • 1
  • N. A. Onishchenko
    • 1
  • M. E. Krasheninnikov
    • 1
  • V. I. Kravchenko
    • 1
  • T. L. Gorshenin
    • 1
  • R. E. Pidtsan
    • 1
  • I. V. Potapov
    • 1
  1. 1.Institute of Transplantology and Artificial OrgansMoscow

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