Skip to main content
SpringerLink
Log in

Recovery of contractile function of cryodamaged rat myocardium after transplantation of fetal cardiomyocytes and predifferentiated bone marrow stromal stem cells

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of cell transplantation into cryodamaged rat myocardium was studied on isolated hearts by increasing functional load to the left ventricle. Transplantation of allogeneic fetal cardiomyocytes improved the function of the left ventricle under conditions of considerably increased preload. Transplantation of autologous mesenchymal stem cells repaired leftventricular function under conditions of increased pre- and afterload.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. B. Bittira, J. Q. Kuang, A. Al-Khaldi, et al., Ann. Thorac. Surg., 74, No. 4, 1154–1160 (2002).

    Google Scholar 

  2. F. R. Eberli, F. Sam, S. Ngoy, et al., J. Mol. Cell. Cardiol., 30, 1443–1447 (1998).

    Google Scholar 

  3. K. Fukuda, Artificial Organs, 25, 187–193 (2001).

    Google Scholar 

  4. H. Kamihata, H. Matsubara, T. Nishiue, et al., Circulation, 104, 1046–1052 (2001).

    Google Scholar 

  5. I. Kingma, E. Harmesen, and H. E. ter Keurs, Int. J. Cardiol., 31, No. 1, 15–22 (1991).

    Google Scholar 

  6. T. Kobayashi, K. Hamano, T. S. Li, et al., J. Surg. Res., 89, 189–195 (2000).

    Google Scholar 

  7. R. K. Li, L. C. Tumiaki, R. G. Weifel, and J. A. G. Mickli, J. Tissue Cult. Methods, 15, 147–154 (1993).

    Google Scholar 

  8. J. R. Neely, H. Liebermeister, and H. E. Morgan, Am. J. Physiol., 212, No. 4, 804–814 (1967).

    Google Scholar 

  9. T. Sakai, R. K. Li, and R. D. Weisel, Ann. Thorac. Surg., 68, No. 6, 2074–2081 (1999).

    Google Scholar 

  10. M. Scorsin, A. A. Hagege, I. Dolizy, et al., Circulation, 98, II151–II156 (1998).

    Google Scholar 

  11. N. Tran, N. Bertrand, Y. Li, et al., Transplant. Proc., 34, 3262–3264 (2002).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Stem Cell Biotechnology, Institute of Transplantation and Artificial Organs, Ministry of Health of the Russian Federation, Moscow

    N. A. Onishchenko, I. V. Potapov, L. V. Bashkina, M. E. Krasheninnikov, V. A. Zaidenov & P. V. Avramov

Authors
  1. N. A. Onishchenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. V. Potapov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. V. Bashkina
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. E. Krasheninnikov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. V. A. Zaidenov
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. P. V. Avramov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 10, pp. 403–407, October, 2004

Rights and permissions

Reprints and permissions

About this article

Cite this article

Onishchenko, N.A., Potapov, I.V., Bashkina, L.V. et al. Recovery of contractile function of cryodamaged rat myocardium after transplantation of fetal cardiomyocytes and predifferentiated bone marrow stromal stem cells. Bull Exp Biol Med 138, 357–360 (2004). https://doi.org/10.1007/s10517-005-0041-8

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-005-0041-8

Key Words

Search

Navigation