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In vitro regulation of cell behavior by calcium phosphates synthesized by the mechanochemical method

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Abstract

Biological activity of eight hydroxyapatite powders synthesized by the mechanochemical method was studied in vitro. Introduction of copper and zinc atoms into synthetic hydroxyapatite structure promotes cell adhesion. Hydroxyapatites obtained by the mechanochemical method are promising base for a new class of materials and coatings with regulated bioactivity for orthopedics and traumatology.

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Authors and Affiliations

  1. Center for Orthopedics and Medical Material Technology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Tomsk

    A. V. Karlov, I. A. Khlusov & N. S. Pozhen’ko

  2. Institute of Hard Body Chemistry and Mechanochemistry, Siberian Division of Russian Academy of Sciences, Novosibirsk

    M. V. Chaikina

Authors
  1. A. V. Karlov
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  2. I. A. Khlusov
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  3. N. S. Pozhen’ko
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  4. M. V. Chaikina
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Corresponding author

Correspondence to I. A. Khlusov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 9, pp. 356–360, September, 2004

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Karlov, A.V., Khlusov, I.A., Pozhen’ko, N.S. et al. In vitro regulation of cell behavior by calcium phosphates synthesized by the mechanochemical method. Bull Exp Biol Med 138, 316–320 (2004). https://doi.org/10.1007/s10517-005-0030-y

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  • DOI: https://doi.org/10.1007/s10517-005-0030-y

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