Skip to main content

Advertisement

SpringerLink
Log in

Preventive and therapeutic effect of complex antioxidant preparation in rats with burn trauma

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The production of blood radicals and activity of superoxide dismutase in erythrocytes increased in rats with contact burn trauma (20%). In animals with burn trauma antioxidant activity of the plasma was much lower, while myeloperoxidase content in the lung tissue and epidermis was higher than in control rats. The complex of antioxidants (Immudzhen) inhibited radical generation at the peak of inflammation (day 4), increased antioxidant activity of the plasma, and normalized myeloperoxidase content in the lung tissue.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. G. I. Klebanov, I. V. Babenkova, Yu. O. Teselkin, et al., Lab. Delo, No. 5, 59–62 (1988).

  2. A. Lyuchi, E. Mikhal’chik, I. Deeva, et al., Vestn. Estet. Med., No. 2, 136–140 (2003).

  3. Z. F. Kharaeva, L. G. Korkina, M. Sh. Mustafaev, and Sh. S. Kudaev, Akt. Probl. Sovr. Stomat. Chel.-Lits. Khir., No. 2, 23– 28 (2002).

  4. N. A. Busch E. M. Zanzot P. M. Loiselle et al. (2000) Infect. Immun. 68 IssueID6 3349–3351

    Google Scholar 

  5. L.-W. Chen Y.-C. Hwang C.-J. Chen et al. (2003) Shock 20 369–374

    Google Scholar 

  6. M. K. Dobke E. A. Deitch T. J. Harner C. R. Baxter (1989) Arch. Surg. 124 856–859

    Google Scholar 

  7. R. A. Greenwald, Handbook of Methods for Oxygen Radical Research, Florida (1986), pp. 291–302.

  8. H. P. Mizra I. Fridovich (1972) J. Biol. Chem. 247 3170

    Google Scholar 

  9. R. L. Sheridan C. M. Ryan L. M. Yin et al. (1996) Burns 24 307–311

    Google Scholar 

  10. F. Takayama T. Egashira Y. Yamanaka (1998) Nippon Yakurigaku Zasshi 111 177–186

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Molecular Biology, Moscow

    E. V. Mikhal’chik, A. V. Ivanova & L. G. Korkina

  2. Department of Physiology, Russian State Medical University, Moscow

    M. V. Anurov, S. M. Titkova & L. Yu. Pen’kov

Authors
  1. E. V. Mikhal’chik
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. V. Ivanova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. V. Anurov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S. M. Titkova
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. L. Yu. Pen’kov
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. L. G. Korkina
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to E. V. Mikhal’chik.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 9, pp. 299–301, September, 2004

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mikhal’chik, E.V., Ivanova, A.V., Anurov, M.V. et al. Preventive and therapeutic effect of complex antioxidant preparation in rats with burn trauma. Bull Exp Biol Med 138, 264–266 (2004). https://doi.org/10.1007/s10517-005-0017-8

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-005-0017-8

Key Words

Search

Navigation