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Activity of cytochrome P450 in children

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Abstract

The 6β-hydroxycortisol/cortisol ratio was measured in 52 children aging 1.1–14.0 years. The maximum increment in this ratio occurred in the age interval of 1.1–2.0 years. During this period, the regression coefficients in the linear (r=0.57; p=0.044) and nonlinear logarithmic models (r=0.56; p=0.049) were similar. At the age of 10–14 years, the examined ratio attained 19.17±17.79.

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Authors and Affiliations

  1. Institute of Molecular Biology and Biophysics, Siberian Division of the Russian Academy of Medical Sciences, Russia

    V. A. Vavilin, E. G. Shchepotina & V. V. Lyakhovich

  2. First Municipal Children Hospital, Russia

    N. A. Manankin

  3. State Medical Academy, Novosibirsk

    L. F. Kaznacheeva

Authors
  1. V. A. Vavilin
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  2. E. G. Shchepotina
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  3. N. A. Manankin
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  4. L. F. Kaznacheeva
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  5. V. V. Lyakhovich
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Corresponding author

Correspondence to V. A. Vavilin.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 9, pp. 272–274, September, 2004

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Vavilin, V.A., Shchepotina, E.G., Manankin, N.A. et al. Activity of cytochrome P450 in children. Bull Exp Biol Med 138, 240–242 (2004). https://doi.org/10.1007/s10517-005-0009-8

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  • DOI: https://doi.org/10.1007/s10517-005-0009-8

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