The possibility of producing large quantities of iodine isotopes of high purity in internal and external targets of a CV-28 cyclotron in reactions on protons and deuterons is studied. The advantage of using low-energy cyclotrons for such purposes is examined. It is shown that the use of a special technology for preparing targets from tellurium and a method of removing the heat released at a target irradiated by a proton beam will make it possible to produce in the CV-28 a large quantity of iodine isotopes in a relatively short time 1–2 h.
Similar content being viewed by others
References
S. N. Dmitriev and N. T. Zaitsev, “Radionuclides for biomedical research. Nuclear data and production methods on charged-particle accelerators,” Fiz. Element. Chast. At. Yadra, 27, No. 4, 977 (1996).
A. Hermanne, M. Sonck, A. Fenyveci, and L. Daraban, “Study on production of 103Pd and characterization of possible contaminants in proton irradiation of 103Rh up to 28 MeV,” Nucl. Instrum. Methods in Phys. Res. B, 170, 281–292 (2000).
F. Tarkanyi, S. Takacs, et al., “Status of the database for production of medical radioisotopes of 103Pd, 123,124I, 201Te by using Rh, Te and Te targets,” J. Nucl. Sci. Techn., No. 2, 1318–1321 (2002).
B. Scholten, Z. Kovacs, F. Tarkanyi, and S. M. Qaim, “Excitation functions of 124Te(p, xn)124,l23I reactions from 6 to 31 MeV with special reference to the production of 124I at a small cyclotron,” Appl. Rad. Isot, 46, No. 4, 255–259 (1995).
R. Barrall, J. Beaver, H. Hupf, et al., “Production of curie quantities of high purity 123I with 15 MeV protons,” Eur. J. Nucl. Med., 6, No. 9, 411–415 (1981).
I. Mahunka, L. Ando, P. Mikecz, et al., “Iodine-123 production at a small cyclotron for medical use,” Radioanal. Nucl. Chem. Lett., 213(2), 135–142 (1996).
A. M. Egorov, A. G. Lymar, I. M. Neklyudov, and Yu. T. Petrusenko, “Compact CV-28 cyclotron and prospects for its use at the National Center for Science at the Kharkov Physicotechnical Institute,” Vopr. At. Nauki Tekhn. Ser. Fiz. Tech. Uskorit., No. 5(50), 120–122 (2008).
Cyclotron Produced Radionuclides: Principles and Practice, Tech. Rep. No. 468, IAEA,Vienna (2009), pp. 167–174.
Cyclotron Produced Radionuclides: Principles and Practice, Tech. Rep. No. 465, IAEA,Vienna (2008), pp. 155–166.
Th. Bastian, H. Coenen, and S. Qaim, “Excitation function of 124Te(d, xn)124,125I reaction from threshold up to 14 MeV: comparative evaluation of nuclear routes for the production of 124I,” Appl. Rad. Isot., 55, 303–308 (2001).
B. Scholten, K. F. Hassan, Z. A. Saleh, et al., “Comparative studies on the production of the medically important radionuclide 124I via p-, d-, 3He- and α-particle induced reaction,” in: Proc. Conf. on Nuclear Data for Science and Technology (2007), pp. 1359–1361.
A. Hohn, F. M. Nortier, B. Scholten, et al., “Excitation functions of 123Te (p, xn) reactions from their respective thresholds up to 100 MeV with special reference to the production of I24I,” Appl. Rad. Isot., 55, 146–156 (2001).
Author information
Authors and Affiliations
Additional information
Translated from Atomnaya Énergiya, Vol. 109, No. 5, pp. 284–288, November, 2010.
Rights and permissions
About this article
Cite this article
Petrusenko, Y.T., Nikolaichuk, L.I., Tutubalin, A.I. et al. Production of medical 123–125I in the CV-28 cyclotron using tellurium targets. At Energy 109, 350–354 (2011). https://doi.org/10.1007/s10512-011-9367-7
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10512-011-9367-7