Abstract
Facilitators and barriers of Pre-exposure Prophylaxis (PrEP) uptake have been established in prior studies; however, most of these studies comprise samples of MSM from metropolitan cities and hypothetical PrEP use. There is a dearth of literature on the uptake factors among rural U.S. MSM who are prescribed PrEP. Thirty-four rural Midwestern MSM who currently take PrEP participated in semi-structured telephone interviews about their barriers and facilitators to their PrEP use. Interviews were analyzed using an inductive thematic analysis approach. There were four barriers: (1) lack of rural dissemination of PrEP information, (2) concern about side and adverse effects of using PrEP, (3) cost of PrEP uptake and engagement, and (4) lack of access to PrEP care and PrEP care quality. Individual and social facilitators that participants utilized to overcome these barriers are discussed. Findings elevate the importance of multilevel interventions that address PrEP adoption from a patient, provider, and healthcare system perspective.
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Al-Tayyib, A. A., Thrun, M. W., Haukoos, J. S., & Walls, N. E. (2014). Knowledge of pre-exposure prophylaxis (PrEP) for HIV prevention among men who have sex with men in Denver, Colorado. AIDS and Behavior,18(S3), 340–347. https://doi.org/10.1007/s10461-013-0553-6.
Audacity Team. (2018). Audacity (version 2.2.2). Retrieved from https://www.audacityteam.org/.
Bacon, O., Gonzalez, R., Andrew, E., Potter, M. B., Iñiguez, J. R., Cohen, S. E., … Fuchs, J. D. (2017). Informing strategies to build PrEP capacity among San Francisco Bay Area clinicians. Journal of Acquired Immune Deficiency Syndromes,74(2), 175–179. https://doi.org/10.1097/QAI.0000000000001182.
Blumenthal, J., Jain, S., Krakower, D., Sun, X., Young, J., Mayer, K., & Haubrich, R. (2015). Knowledge is power! Increased provider knowledge scores regarding pre-exposure prophylaxis (PrEP) are associated with higher rates of PrEP prescription and future intent to prescribe PrEP. AIDS and Behavior,19(5), 802–810. https://doi.org/10.1007/s10461-015-0996-z.
Braun, V., & Clarke, V. (2006). Using thematic analysis in psychology. Qualitative Research in Psychology,3(2), 77–101. https://doi.org/10.1191/1478088706qp063oa.
Brownell, J. W. (1960). The cultural Midwest. Journal of Geography,59(2), 81–85. https://doi.org/10.1080/00221346008982048.
Centers for Disease Control and Prevention. (2018a). HIV and gay and bisexual men. Retrieved from https://www.cdc.gov/hiv/group/msm/index.html.
Centers for Disease Control and Prevention. (2018b). Preexposure prophylaxis for the prevention of HIV infection in the United States—2017 Update: A clinical practice guideline. Retrieved from https://www.cdc.gov/hiv/pdf/risk/prep/cdc-hiv-prep-guidelines-2017.pdf.
Centers for Disease Control and Prevention. (2019). HIV in the United States by region. Retrieved from https://www.cdc.gov/hiv/statistics/overview/geographicdistribution.html.
Collins, S. P., McMahan, V. M., & Stekler, J. D. (2017). The impact of HIV pre-exposure prophylaxis (PrEP) use on the sexual health of men who have sex with men: A qualitative study in Seattle, WA. International Journal of Sexual Health,29(1), 55–68. https://doi.org/10.1080/19317611.2016.1206051.
Currin, J. M., Hubach, R. D., Crethar, H. C., Hammer, T. R., Lee, H.-S., & Larson, M. (2018a). Barriers to accessing mental healthcare for gay and bisexual men living in Oklahom. Sexuality Research and Social Policy. https://doi.org/10.1007/s13178-018-0321-5.
Currin, J. M., Hubach, R. D., Crethar, H. C., Hammer, T. R., Lee, H.-S., & Larson, M. (2018b). Barriers to accessing mental healthcare for gay and bisexual men living in Oklahoma. Sexuality Research and Social Policy. https://doi.org/10.1007/s13178-018-0321-5.
Dishy, A. (2018). r/askgaybros: PrEP participation and health information dissemination on Reddit. The iJournal: Graduate Student Journal of the Faculty of Information. https://doi.org/10.7448/IAS.18.4.19983.
Dubov, A., Altice, F. L., & Fraenkel, L. (2018). An information–Motivation–Behavioral skills model of PrEP uptake. AIDS and Behavior,22(11), 3603–3616. https://doi.org/10.1007/s10461-018-2095-4.
Farmer, G. W., Blosnich, J. R., Jabson, J. M., & Matthews, D. D. (2016). Gay acres: Sexual orientation differences in health indicators among rural and nonrural individuals. Journal of Rural Health,32, 321–331. https://doi.org/10.1111/jrh.12161.
Finlayson, T., Cha, S., Xia, M., Trujillo, L., Denson, D., Prejean, J., … National HIV Behavioral Surveillance Study Group. (2019). Changes in HIV preexposure prophylaxis awareness and use among men who have sex with men—20 urban areas, 2014 and 2017. Morbidity and Mortality Weekly Report,68(27), 597–603. https://doi.org/10.15585/mmwr.mm6827a1.
Fisher, C. M., Irwin, J. A., & Coleman, J. D. (2014). LGBT health in Midlands: A rural/urban comparison of basic health indicators. Journal of Homosexuality,61, 1062–1090. https://doi.org/10.1080/00918369.2014.872487.
Gates, G. J. (2013). Geography of the LGBT population. In A. K. Bamule (Ed.), International handbook on the demography of sexuality (pp. 229–242). Dordrecht, the Netherlands: Springer.
Gates, G. J. (2014). LGBT demographics: Comparisons among population-based surveys. Retrieved from https://williamsinstitute.law.ucla.edu/wp-content/uploads/lgbt-demogs-sep-2014.pdf.
Grant, R. M., Anderson, P. L., McMahan, V., Liu, A., Amico, K. R., Mehrotra, M., … Glidden, D. V. (2014). Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: A cohort study. Lancet Infectious Diseases,14(9), 820–829. https://doi.org/10.1016/s1473-3099(14)70847-3.
Grant, R. M., Lama, J. R., Anderson, P. L., McMahan, V., Liu, A. Y., Vargas, L., … Glidden, D. V. (2010). Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. New England Journal of Medicine,363(27), 2587–2599. https://doi.org/10.1056/nejmoa1011205.
Grimm, J., & Schwartz, J. (2019). “It’s like birth control for HIV”: Communication and stigma for gay men on PrEP. Journal of Homosexuality,66(9), 1179–1197. https://doi.org/10.1080/00918369.2018.1495978.
Haire, B. (2015). Preexposure prophylaxis-related stigma: Strategies to improve uptake and adherence—A narrative review. HIV/AIDS: Research and Palliative Care, 7, 241–249. https://doi.org/10.2147/hiv.s72419.
Hammack, P. L., Meyer, I. H., Krueger, E. A., Lightfoot, M., & Frost, D. M. (2018). HIV testing and pre-exposure prophylaxis (PrEP) use, familiarity, and attitudes among gay and bisexual men in the United States: A national probability sample of three birth cohorts. PLoS ONE,13(9), e0202806. https://doi.org/10.1371/journal.pone.0202806.
Hammack, P. L., Toolis, E. E., Wilson, B. D. M., Clark, R. C., & Frost, D. M. (2019). Making meaning of the impact of pre-exposure prophylaxis (PrEP) on public health and sexual culture: Narratives of three generations of gay and bisexual men. Archives of Sexual Behavior,48(4), 1041–1058. https://doi.org/10.1007/s10508-019-1417-6.
Hannaford, A., Lipshie-Williams, M., Starrels, J. L., Arnsten, J. H., Rizzuto, J., Cohen, P., … Patel, V. V. (2018). The use of online posts to identify barriers to and facilitators of HIV pre-exposure prophylaxis (PrEP) among men who have sex with men: A comparison to a systematic review of the peer-reviewed literature. AIDS and Behavior,22(4), 1080–1095. https://doi.org/10.1007/s10461-017-2011-3.
Hasenbush, A., Flores, A., Kastanis, A., Sears, B., & Gates, G. (2014). The LGBT divide: A data portrait of LGBT people in the Midwestern, Mountain & Southern states. Retrieved from Los Angeles: http://williaminstitute.law.ucla.edu/wp-content/uploads/LGBT-divide-Dec-2014.pdf.
Hickey, W. (2014). Which states are in the Midwest? Retrieved from https://fivethirtyeight.com/features/what-states-are-in-the-midwest/.
Hoffman, S., Guidry, J. A., Collier, K. L., Mantell, J. E., Boccher-Lattimore, D., Kaighobadi, F., & Sandfort, T. G. M. (2016). A clinical home for preexposure prophylaxis: Diverse health care providers’ perspectives on the “purview paradox. Journal of the International Association of Providers of AIDS Care,15(1), 59–65. https://doi.org/10.1177/2325957415600798.
Hosek, S. G., Siberry, G., Bell, M., Lally, M., Kapogiannis, B., Green, K., … Adolsecent Trials Network for HIV/AIDS Interventions. (2013). The acceptability and feasibility of an HIV preexposure prophylaxis (PrEP) trial with young men who have sex with men. Journal of Acquired Immune Deficiency Syndromes,62(4), 447–456. https://doi.org/10.1097/qai.0b013e3182801081.
Hubach, R. D., Currin, J. M., Sanders, C. A., Durham, A. R., Kavanaugh, K. E., Wheeler, D. L., & Croff, J. M. (2017). Barriers to access and adoption of pre-exposure prophylaxis for the prevention of HIV among men who have sex with men (MSM) in a relatively rural state. AIDS Education and Prevention,29(4), 315–329. https://doi.org/10.1521/aeap.2017.29.4.315.
Hubach, R. D., Dodge, B., Li, M. J., Schick, V., Herbenick, D., Ramos, W. D., … Reece, M. (2015a). Loneliness, HIV-related stigma, and condom use among a predominantly rural sample of HIV-positive men who have sex with men (MSM). AIDS Education and Prevention,27(1), 72–83. https://doi.org/10.1521/aeap.2015.27.1.72.
Hubach, R. D., Dodge, B., Schick, V., Ramos, W. D., Herbenick, D., Li, M. J., … Reece, M. (2015b). Experiences of HIV-positive gay, bisexual and other men who have sex with men residing in relatively rural areas. Culture, Health & Sexuality,17(7), 795–809. https://doi.org/10.1080/13691058.2014.994231.
IBM Corp. (2016). SPSS Statistical for Windows (version 24). Retrieved from https://www.ibm.com/analytics/spss-statistics-software.
John, S. A., Rendina, H. J., Grov, C., & Parsons, J. T. (2017). Home-based pre-exposure prophylaxis (PrEP) services for gay and bisexual men: An opportunity to address barriers to PrEP uptake and persistence. PLoS ONE,12(12), e0189794. https://doi.org/10.1371/journal.pone.0189794.
Kay, E. S., & Pinto, R. M. (2020). Is insurance a barrier to HIV preexposure prophylaxis? Clarifying the issue. American Journal of Public Health,110(1), 61–64. https://doi.org/10.2105/ajph.2019.305389.
Kelley, C. F., Kahle, E., Siegler, A., Sanchez, T., Del Rio, C., Sullivan, P. S., & Rosenberg, E. S. (2015). Applying a PrEP continuum of care for men who have sex with men in Atlanta, Georgia. Clinical Infectious Diseases,61(10), 1590–1597. https://doi.org/10.1093/cid/civ664.
Krakower, D., Ware, N., Mitty, J. A., Maloney, K., & Mayer, K. H. (2014). HIV providers’ perceived barriers and facilitators to implementing pre-exposure prophylaxis in care settings: A qualitative study. AIDS and Behavior,18(9), 1712–1721. https://doi.org/10.1007/s10461-014-0839-3.
Li, M. J., Hubach, R. D., & Dodge, B. (2015). Social milieu and mediators of loneliness among gay and bisexual men in rural Indiana. Journal of Gay & Lesbian Mental Health,19(4), 331–346. https://doi.org/10.1080/19359705.2015.1033798.
Liu, A. Y., Cohen, S. E., Vittinghoff, E., Anderson, P. L., Doblecki-Lewis, S., Bacon, O., … Kolber, M. A. (2016). Preexposure prophylaxis for HIV infection integrated with municipal-and community-based sexual health services. JAMA Internal Medicine,176(1), 75–84. https://doi.org/10.1001/jamainternmed.2015.4683.
Liu, A. Y., Colfax, G., Cohen, S., Bacon, O., Kolber, M., Amico, K. R., Mugavero, M., Grant, R., & Buchbinder, S. (2012). The spectrum of engagement in HIV prevention: Proposal for a PrEP cascade. Paper presented at the International Conference on HIV Treatment and Prevention Adherence.
Mabire, X., Puppo, C., Morel, S., Mora, M., Rojas Castro, D., Chas, J., … Préau, M. (2019). Pleasure and PrEP: Pleasure-seeking plays a role in prevention choices and could lead to PrEP initiation. American Journal of Men’s Health,13(1), 1–14. https://doi.org/10.1177/1557988319827396.
Maloney, K. M., Krakower, D. S., Ziobro, D., Rosenberger, J. G., Novak, D., & Mayer, K. H. (2017). Culturally competent sexual healthcare as a prerequisite for obtaining preexposure prophylaxis: Findings from a qualitative study. LGBT Health,4(4), 310–314. https://doi.org/10.1089/lgbt.2016.0068.
Marcus, J. L., Hurley, L. B., Dentoni-Lasofsky, D., Ellis, C. G., Silverberg, M. J., Slome, S., … Volk, J. E. (2019). Barriers to preexposure prophylaxis use among individuals with recently acquired HIV infection in Northern California. AIDS Care,31(5), 536–544. https://doi.org/10.1080/09540121.2018.1533238.
Maxwell, S., Gafos, M., & Shahmanesh, M. (2019). Pre-exposure prophylaxis use and medication adherence among men who have sex with men: A systematic review of the literature. Journal of the Association of Nurses in AIDS Care,30(4), e38–e61. https://doi.org/10.1097/JNC.0000000000000105.
Mayer, K. H., Chan, P. A., Patel, R., Flash, C. A., & Krakower, D. S. (2018). Evolving models and ongoing challenges for HIV pre-exposure prophylaxis implementation in the United States. Journal of Acquired Immune Deficiency Syndromes,77(2), 119–127. https://doi.org/10.1097/QAI.0000000000001579.
McCormack, S., Dunn, D. T., Desai, M., Dolling, D. I., Gafos, M., Gilson, R., … Gill, O. N. (2016). Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): Effectiveness results from the pilot phase of a pragmatic open-label randomised trial. The Lancet,387(10013), 53–60. https://doi.org/10.1016/s0140-6736(15)00056-2.
McKinney, M. M. (2002). Variations in rural AIDS epidemiology and service delivery models in the United States. The Journal of Rural Health,18(3), 455–466. https://doi.org/10.1111/j.1748-0361.2002.tb00910.x.
Molina, J.-M., Capitant, C., Spire, B., Pialoux, G., Cotte, L., Charreau, I., … Delfraissy, J. F. (2015). On-demand preexposure prophylaxis in men at high risk for HIV-1 infection. New England Journal of Medicine,373(23), 2237–2246. https://doi.org/10.1056/NEJMoa1506273.
Movement Advancement Project. (2019). Where we call home: LGBT people in rural America. Retrieved from http://www.lgbtmap.org/file/lgbt-rural-report.pdf.
Nunn, A. S., Brinkley-Rubinstein, L., Oldenburg, C. E., Mayer, K. H., Mimiaga, M., Patel, R., & Chan, P. A. (2017). Defining the HIV pre-exposure prophylaxis care continuum. AIDS,31(5), 731–734. https://doi.org/10.1097/QAD.0000000000001385.
Owens, D. K., Davidson, K. W., Krist, A. H., Barry, M. J., Cabana, M., Caughey, A. B., … Wong, J. B. (2019). Preexposure prophylaxis for the prevention of HIV infection: US Preventive Services Task Force recommendation statement. Journal of the American Medical Association,321(22), 2203–2213. https://doi.org/10.1001/jama.2019.6390.
Patel, R. R., Chan, P. A., Harrison, L. C., Mayer, K. H., Nunn, A., Mena, L. A., & Powderly, W. G. (2018). Missed opportunities to prescribe HIV pre-exposure prophylaxis by primary care providers in Saint Louis, Missouri. LGBT Health,5(4), 250–256. https://doi.org/10.1089/lgbt.2017.0101.
Patel, R. R., Mena, L., Nunn, A., McBride, T., Harrison, L. C., Oldenburg, C. E., … Chan, P. A. (2017). Impact of insurance coverage on utilization of pre-exposure prophylaxis for HIV prevention. PLoS ONE,12(5), e0178737. https://doi.org/10.1371/journal.pone.0178737.
Pellowski, J. A. (2013). Barriers to care for rural people living with HIV: A review of domestic research and health care models. Journal of the Association of Nurses in AIDS Care,24(5), 422–437. https://doi.org/10.1016/j.jana.2012.08.007.
Petroll, A. E., Walsh, J. L., Owczarzak, J. L., McAuliffe, T. L., Bogart, L. M., & Kelly, J. A. (2017). PrEP awareness, familiarity, comfort, and prescribing experience among US primary care providers and HIV specialists. AIDS and Behavior,21(5), 1256–1267. https://doi.org/10.1007/s10461-016-1625-1.
Pinto, R. M., Berringer, K. R., Melendez, R., & Mmeje, O. (2018). Improving PrEP implementation through multilevel interventions: A synthesis of the literature. AIDS and Behavior,22(11), 3681–3691. https://doi.org/10.1007/s10461-018-2184-4.
Pinto, R. M., Lacombe-Duncan, A., Kay, E. S., & Berringer, K. R. (2019). Expanding knowledge about implementation of pre-exposure prophylaxis (PrEP): A methodological review. AIDS and Behavior, 23, 2761–2778. https://doi.org/10.1007/s10461-019-02577-7.
Qu, D., Zhong, X., Lai, M., Dai, J., Liang, H., & Huang, A. (2019). Influencing factors of pre-exposure prophylaxis self-efficacy among men who have sex with men. American Journal of Men’s Health,13(2). https://doi.org/10.1177/1557988319847088.
Rice, W. S., Stringer, K. L., Sohail, M., Crockett, K. B., Atkins, G. C., Kudroff, K., … Turan, B. (2019). Accessing pre-exposure prophylaxis (PrEP): Perceptions of current and potential PrEP users in Birmingham, Alabama. AIDS and Behavior, 23, 2966–2979. https://doi.org/10.1007/s10461-019-02591-9.
Rosenkrantz, D. E., Black, W. W., Abreu, R. L., Aleshire, M. E., & Fallin-Bennett, K. (2017). Health and health care of rural sexual and gender minorities: A systematic review. Stigma and Health,2(3), 229–243. https://doi.org/10.1037/sah0000055.
San Francisco AIDS Foundation. (2018). The questions about PrEP.
Schafer, K. R., Albrecht, H., Dillingham, R., Hogg, R. S., Jaworsky, D., Kasper, K., … Ohl, M. E. (2017). The continuum of HIV care in rural communities in the United States and Canada: What is known and future research directions. Journal of Acquired Immune Deficiency Syndromes,75(1), 35–44.
Schnarrs, P. W., Gordon, D., Martin-Valenzuela, R., Sunil, T., Delgado, A. J., Glidden, D., … McAdams, J. (2018). Perceived social norms about oral PrEP use: Differences between African-American, Latino and White gay, bisexual and other men who have sex with men in Texas. AIDS and Behavior,22(11), 3588–3602. https://doi.org/10.1007/s10461-018-2076-7.
Schwartz, J., & Grimm, J. (2017). PrEP on Twitter: Information, barriers, and stigma. Health Communication,32(4), 509–516. https://doi.org/10.1080/10410236.2016.1140271.
Schwartz, J., & Grimm, J. (2019). Stigma communication surrounding PrEP: The experiences of a sample of men who have sex with men. Health Communication,34(1), 84–90. https://doi.org/10.1080/10410236.2017.1384430.
Sharpe, J. D., & Kamara, M. T. (2018). A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis. Sexual Health,15, 587–594. https://doi.org/10.1071/SH18120.
Shortridge, J. R. (1987). Changing usage of four American regional labels. Annals of the Association of American Geographers,77(3), 325–336. https://doi.org/10.1111/j.1467-8306.1987.tb00162.x.
Siegler, A. J., Bratcher, A., & Weiss, K. M. (2019). Geographic access to preexposure prophylaxis clinics among men who have sex with men in the United States. American Journal of Public Health, 109, 1216–1223. https://doi.org/10.2105/ajph.2019.305172.
Siegler, A. J., Bratcher, A., Weiss, K. M., Mouhanna, F., Ahlschlager, L., & Sullivan, P. S. (2018). Location location location: An exploration of disparities in access to publicly listed pre-exposure prophylaxis clinics in the United States. Annals of Epidemiology,28(12), 858–864. https://doi.org/10.1016/j.annepidem.2018.05.006.
SocioCultural Research Consultants. (2018). Dedoose (version 8.1.8). Retrieved from https://www.dedoose.com/.
Sullivan, P. S., & Siegler, A. J. (2018). Getting pre-exposure prophylaxis (PrEP) to the people: Opportunities, challenges and emerging models of PrEP implementation. Sexual Health,15(6), 522–527. https://doi.org/10.1071/SH18103.
Sun, C. J., Anderson, K. M., Bangsberg, D., Toevs, K., Morrison, D., Wells, C., … Nicolaidis, C. (2019). Access to HIV pre-exposure prophylaxis in practice settings: A qualitative study of sexual and gender minority adults’ perspectives. Journal of General Internal Medicine,34(4), 535–543. https://doi.org/10.1007/s11606-019-04850-w.
Touger, R., & Wood, B. R. (2019). A review of telehealth innovations for HIV pre-exposure prophylaxis (PrEP). Current HIV/AIDS Report,16(1), 113–119. https://doi.org/10.1007/s11904-019-00430-z.
Tripathi, A., Whiteside, O. Y., & Duffus, W. A. (2013). Perceptions and attitudes about preexposure prophylaxis among seronegative partners and the potential of sexual disinhibition. Southern Medical Journal,106(10), 558–564. https://doi.org/10.1097/SMJ.0000000000000010.
United States Census Bureau. (2019). Geographic terms and concepts—Census divisions and census regions. Retrieved from https://www.census.gov/geo/reference/gtc/gtc_census_divreg.html.
Volk, J. E., Marcus, J. L., Phengrasamy, T., Blechinger, D., Nguyen, D. P., Follansbee, S., & Hare, C. B. (2015). No new HIV infections with increasing use of HIV preexposure prophylaxis in a clinical practice setting. Clinical Infectious Diseases,61(10), 1601–1603. https://doi.org/10.1093/cid/civ778.
Waldorf, B. S. (2006). A continuous multi-dimensional measure of rurality: Moving beyond threshold measures. Paper presented at the meeting of the Association of Agricultural Economics, Long Beach, CA. http://ageconsearch.umn.edu/record/21383/files/sp06wa02.pdf.
Waldorf, B. S., & Kim, A. (2015). Defining and measuring rurality in the US: From typologies to continuous indices. Paper presented at the Workshop on Rationalizing Rural Area Classifications, Washington, DC. http://sites.nationalacademies.org/cs/groups/dbassesite/documents/webpage/dbasse_167036.pdf.
Walsh, J. L. (2019). Applying the information–Motivation–Behavioral skills model to understand PrEP intentions and use among men who have sex with men. AIDS and Behavior,23(7), 1904–1916. https://doi.org/10.1007/s10461-018-2371-3.
Walsh, J. L., & Petroll, A. E. (2017). Factors related to pre-exposure prophylaxis prescription by US primary care physicians. American Journal of Preventive Medicine,52(6), 165–172. https://doi.org/10.1016/j.amepre.2017.01.025.
Whitfield, T. H. F., John, S. A., Rendina, H. J., Grov, C., & Parsons, J. T. (2018). Why I quit pre-exposure prophylaxis (PrEP)? A mixed-method study exploring reasons for PrEP discontinuation and potential re-initiation among gay and men. AIDS and Behavior,22(11), 3566–3575. https://doi.org/10.1007/s10461-018-2045-1.
Woodell, B. (2018). Understanding sexual minority health disparities in rural areas. Sociology Compass,12(2), e12553. https://doi.org/10.1111/soc4.12553.
Acknowledgements
We would like to acknowledge the Center for Sexual Health Promotion at Indiana University for funding this study. We would like to acknowledge Megan Hess, Kody Sexton, and Eva Voorheis for transcribing interviews. We would like to acknowledge our recruitment contacts and participants for sharing the study with their social networks.
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This study was funded by the Center for Sexual Health Promotion at Indiana University.
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Owens, C., Hubach, R.D., Williams, D. et al. Facilitators and Barriers of Pre-exposure Prophylaxis (PrEP) Uptake Among Rural Men who have Sex with Men Living in the Midwestern U.S.. Arch Sex Behav 49, 2179–2191 (2020). https://doi.org/10.1007/s10508-020-01654-6
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DOI: https://doi.org/10.1007/s10508-020-01654-6