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An Evolutionary Approach Offers a Fresh Perspective on the Relationship Between Oral Contraception and Sexual Desire

Archives of Sexual Behavior volume 42, pages 1369–1375 (2013)Cite this article

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References

  • Alvergne, A., & Lummaa, V. (2010). Does the contraceptive pill alter mate choice in humans? Trends in Ecology & Evolution, 25, 171–179.

    Article  Google Scholar 

  • Andersson, M. (1994). Sexual selection. Princeton, NJ: Princeton University Press.

    Google Scholar 

  • Bancroft, J., Sherwin, B. B., Alexander, G. M., Davidson, D. W., & Walker, A. (1991). Oral contraceptives, androgens, and the sexuality of young women. II. The role of androgens. Archives of Sexual Behavior, 20, 121–135.

    Article  PubMed  Google Scholar 

  • Basson, R. (2008). Women’s sexual function and dysfunction: Current uncertainties, future directions. International Journal of Impotence Research, 20, 466–478.

    Article  PubMed  Google Scholar 

  • Burrows, L. J., Basha, M., & Goldstein, A. T. (2012). The effects of hormonal contraceptives on female sexuality: A review. Journal of Sexual Medicine, 9, 2213–2223.

    Article  PubMed  Google Scholar 

  • Caruso, S., Agnello, C., Intelisano, G., Farina, M., Di Mari, L., Sparacino, L., & Cianci, A. (2005). Prospective study on sexual behavior of women using 30 μg ethinylestradiol and 3 mg drospirenone oral contraceptive. Contraception, 72, 19–23.

  • Cobey, K. D., & Buunk, A. P. (2012). Conducting high-quality research on the psychological impact of oral contraceptive use. Contraception, 86, 330–331.

    Article  PubMed  Google Scholar 

  • Cobey, K. D., Buunk, A. P., Roberts, S. C., Klipping, C., Appels, N., Zimmerman, Y., … Pollet, T. V. (2012). Reported jealousy differs as a function of menstrual cycle stage and contraceptive pill use: A within-subjects investigation. Evolution and Human Behavior, 33, 395–401.

    Google Scholar 

  • Cobey, K. D., Pollet, T. V., Roberts, S. C., & Buunk, A. P. (2011). Hormonal birth control use and relationship jealousy: Evidence for estrogen dosage effects. Personality and Individual Differences, 50, 315–317.

    Article  Google Scholar 

  • Davis, A. R., & Castano, P. M. (2004). Oral contraceptives and libido in women. Annual Review of Sex Research, 15, 297–320.

    PubMed  Google Scholar 

  • Dennerstein, L. (1997). Sexuality, hormones and the menopausal transition. Maturitas, 26, 83–93.

    Article  PubMed  Google Scholar 

  • Dennerstein, L., Lehert, P., & Dudley, E. (2001). Short scale to measure female sexuality: Adapted from McCoy Female Sexuality Questionnaire. Journal of Sex and Marital Therapy, 27, 339–351.

    Article  PubMed  Google Scholar 

  • Feinberg, D. R., Jones, B. C., Law-Smith, M. J., Moore, F. R., DeBruine, L. M., Cornwell, R. E., … Perrett, D. I. (2006). Menstrual cycle, trait estrogen level, and masculinity preferences in the human voice. Hormones and Behavior, 49, 215–222.

    Google Scholar 

  • Foerster, K., Delhey, K., Johnsen, A., Lifjeld, J. T., & Kempenaers, B. (2003). Females increase offspring heterozygosity and fitness through extra-pair matings. Nature, 425, 714–717.

    Article  PubMed  Google Scholar 

  • Fortenberry, J. D., & Hensel, D. J. (2011). The association of sexual interest and sexual behaviors among adolescent women: A daily diary perspective. Hormones and Behavior, 59, 739–744.

    Article  PubMed Central  PubMed  Google Scholar 

  • Freeman-Gallant, C. R., Wheelwright, N. T., Meiklejohn, K. E., & Sollecito, S. V. (2006). Genetic similarity, extrapair paternity, and offspring quality in Savannah sparrows (Passerculus sandwichensis). Behavioral Ecology, 17, 952–958.

    Article  Google Scholar 

  • Gambrell, R. D., Bernard, D. M., Sanders, B. I., Vanderburg, N., & Buxton, S. J. (1976). Changes in sexual drives of patients on oral contraceptives. Journal of Reproductive Medicine, 17, 165–171.

    PubMed  Google Scholar 

  • Gangestad, S. W., & Thornhill, R. (2008). Human oestrus. Proceedings of the Royal Society B-Biological Sciences, 275, 991–1000.

    Article  PubMed Central  Google Scholar 

  • Garver-Apgar, C. E., Gangestad, S. W., Thornhill, R., Miller, R. D., & Olp, J. J. (2006). Major histocompatibility complex alleles, sexual responsivity, and unfaithfulness in romantic couples. Psychological Science, 17, 830–835.

    Article  PubMed  Google Scholar 

  • Havlicek, J., & Roberts, S. C. (2009). MHC-correlated mate choice in humans: A review. Psychoneuroendocrinology, 34, 497–512.

    Article  PubMed  Google Scholar 

  • Havlicek, J., Roberts, S. C., & Flegr, J. (2005). Women’s preference for dominant male odour: Effects of menstrual cycle and relationship status. Biology Letters, 1, 256–259.

    Article  PubMed Central  PubMed  Google Scholar 

  • Havlicek, J., Saxton, T. K., Roberts, S. C., Jozifkova, E., Lhota, S., Valentova, J., & Flegr, J. (2008). He sees, she smells? Male and female reports of sensory reliance in mate choice and non-mate choice contexts. Personality and Individual Differences, 45, 565–570.

    Google Scholar 

  • Jones, B. C., DeBruine, L. M., Perrett, D. I., Little, A. C., Feinberg, D. R., & Smith, M. J. L. (2008). Effects of menstrual cycle phase on face preferences. Archives of Sexual Behavior, 37, 78–84.

    Article  PubMed  Google Scholar 

  • Jones, B. C., Vukovic, J., Little, A. C., Roberts, S. C., & DeBruine, L. M. (2011). Circum-menopausal changes in women’s preferences for sexually dimorphic shape cues in peer-aged faces. Biological Psychology, 87, 453–455.

    Article  PubMed  Google Scholar 

  • Levine, S. B. (2003). The nature of sexual desire: A clinician’s perspective. Archives of Sexual Behavior, 32, 279–285.

    Article  PubMed  Google Scholar 

  • Little, A. C., Burriss, R. P., Petrie, M., Jones, B. C., & Roberts, S. C. (2013). Oral contraceptive use in women changes preferences for male facial masculinity and is associated with partner facial masculinity. Psychoneuroendocrinology. doi:10.1016/j.psyneuen.2013.02.014.

    PubMed  Google Scholar 

  • Little, A. C., Saxton, T. K., Roberts, S. C., Jones, B. C., DeBruine, L. M., Vukovic, J., … Chenore, T. (2010). Women’s preferences for masculinity in male faces are highest during reproductive age-range and lower around puberty and post-menopause. Psychoneuroendrocrinology, 35, 912–920.

  • McCoy, N. L. (2000). The McCoy Female Sexuality Questionnaire. Quality of Life Research, 9, 739–745.

    Article  Google Scholar 

  • Milinski, M. (2006). The major histocompatibility complex, sexual selection, and mate choice. Annual Review of Ecology Evolution and Systematics, 37, 159–186.

    Article  Google Scholar 

  • Mosher, W. D., & Jones, J. (2010). Use of contraception in the United States: 1982–2008. Washington, DC: National Center for Health Statistics.

    Google Scholar 

  • Panzer, C., Wise, S., Fantini, G., Kang, D. W., Munarriz, R., Guay, A., & Goldstein, I. (2006). Impact of oral contraceptives on sex hormone-binding globulin and androgen levels: A retrospective study in women with sexual dysfunction. Journal of Sexual Medicine, 3, 104–113.

    Google Scholar 

  • Pastor, Z., Holla, K., & Chmel, R. (2013). The influence of combined oral contraceptives on female sexual desire: A systematic review. European Journal of Contraception & Reproductive Health Care, 18, 27–43.

    Article  Google Scholar 

  • Penke, L., & Asendorpf, J. B. (2008). Beyond global sociosexual orientations: A more differentiated look at sociosexuality and its effects on courtship and romantic relationships. Journal of Personality and Social Psychology, 95, 1113–1135.

    Article  PubMed  Google Scholar 

  • Penn, D. J. (2002). The scent of genetic compatibility: Sexual selection and the major histocompatibility complex. Ethology, 108, 1–21.

    Article  Google Scholar 

  • Penton-Voak, I. S., Perrett, D. I., Castles, D. L., Kobayashi, T., Burt, D. M., Murray, L. K., & Minamisawa, R. (1999). Menstrual cycle alters face preference. Nature, 399, 741–742.

    Google Scholar 

  • Petrie, M., & Kempenaers, B. (1998). Extra-pair paternity in birds: Explaining variation between species and populations. Trends in Ecology & Evolution, 13, 52–58.

    Article  Google Scholar 

  • Roberts, S. C. (2009). Complexity and context of MHC-correlated mating preferences in wild populations. Molecular Ecology, 18, 3121–3123.

    Article  PubMed  Google Scholar 

  • Roberts, S. C., Ferdenzi, C., Kralevich, A., Little, A. C., Jones, B. C., DeBruine, L. M., & Havlicek J. (2011). Body odor quality predicts behavioral attractiveness in humans. Archives of Sexual Behavior, 40, 1111–1117.

    Google Scholar 

  • Roberts, S. C., & Gosling, L. M. (2003). Genetic similarity and quality interact in mate choice decisions by female mice. Nature Genetics, 35, 103–106.

    Article  PubMed  Google Scholar 

  • Roberts, S. C., Gosling, L. M., Carter, V., & Petrie, M. (2008a). MHC-correlated odour preferences in humans and the use of oral contraceptives. Proceedings of the Royal Society B-Biological Sciences, 275, 2715–2722.

    Article  PubMed Central  Google Scholar 

  • Roberts, S. C., Klapilová, K., Little, A. C., Burriss, R. P., Jones, B. C., DeBruine, L. M., … Havlíček, J. (2012). Relationship satisfaction and outcome in women who meet their partner while using oral contraception. Proceedings of the Royal Society B-Biological Sciences, 279, 1430–1436.

  • Roberts, S. C., & Little, A. C. (2008). Good genes, complementary genes and human mate preferences. Genetica, 134, 31–43.

    Article  PubMed  Google Scholar 

  • Roberts, G., Newell, F., Simoes-Franklin, C., & Garavan, H. (2008b). Menstrual cycle phase modulates cognitive control over male but not female stimuli. Brain Research, 1224, 79–87.

    Article  PubMed  Google Scholar 

  • Roney, J. R., & Simmons, Z. L. (2008). Women’s estradiol predicts preference for facial cues of men’s testosterone. Hormones and Behavior, 53, 14–19.

    Article  PubMed  Google Scholar 

  • Rosen, R., Brown, C., Heiman, J., Leiblum, S., Meston, C., Shabsigh, R., … D’Agostino, R. (2000). The Female Sexual Function Index (FSFI): A multidimensional self-report instrument for the assessment of female sexual function. Journal of Sex & Marital Therapy, 26, 191-208.

  • Sanders, S. A., Graham, C. A., Bass, J. L., & Bancroft, J. (2001). A prospective study of the effects of oral contraceptives on sexuality and well-being and their relationship to discontinuation. Contraception, 64, 51–58.

    Article  PubMed  Google Scholar 

  • Saxton, T. K., Kohoutova, D., Roberts, S. C., Jones, B. C., DeBruine, L. M., & Havlicek, J. (2010). Age, puberty and attractiveness judgments in adolescents. Personality and Individual Differences, 49, 857–862.

    Article  Google Scholar 

  • Schaffir, J. (2006). Hormonal contraception and sexual desire: A critical review. Journal of Sex and Marital Therapy, 32, 305–314.

    Article  PubMed  Google Scholar 

  • Schwensow, N., Fietz, J., Dausmann, K., & Sommer, S. (2008). MHC-associated mating strategies and the importance of overall genetic diversity in an obligate pair-living primate. Evolutionary Ecology, 22, 617–636.

    Article  Google Scholar 

  • Setchell, J. M., & Huchard, E. (2010). The hidden benefits of sex: Evidence for MHC-associated mate choice in primate societies. BioEssays, 32, 940–948.

    Article  PubMed  Google Scholar 

  • Spector, I. P., Carey, M. P., & Steinberg, L. (1996). The Sexual Desire Inventory: Development, factor structure, and evidence of reliability. Journal of Sex and Marital Therapy, 22, 175–190.

    Article  PubMed  Google Scholar 

  • Stearns, S. C., Nesse, R. M., Govindaraju, D. R., & Ellison, P. T. (2010). Evolutionary perspectives on health and medicine. Proceedings of the National Academy of Sciences, 107, 1691–1695.

    Article  Google Scholar 

  • Wallwiener, C. W., Wallwiener, L.-M., Seeger, H., Mueck, A. O., Bitzer, J., & Wallwiener, M. (2010). Prevalence of sexual dysfunction and impact of contraception in female German medical students. Journal of Sexual Medicine, 7, 2139–2148.

    Article  PubMed  Google Scholar 

  • Wedekind, C., & Füri, S. (1997). Body odour preferences in men and women: Do they aim for specific MHC combinations or simply heterozygosity? Proceedings of the Royal Society B-Biological Sciences, 264, 1471–1479.

    Article  PubMed Central  Google Scholar 

  • Wedekind, C., Seebeck, T., Bettens, F., & Paepke, A. J. (1995). MHC-dependent mate preferences in humans. Proceedings of the Royal Society B-Biological Sciences, 260, 245–249.

    Article  Google Scholar 

  • Welling, L. L. M., Puts, D. A., Roberts, S. C., Little, A. C., & Burriss, R. P. (2012). Hormonal contraceptive use and mate retention behavior in women and their male partners. Hormones and Behavior, 61, 114–120.

    Article  PubMed  Google Scholar 

  • Williams, J. R., & Lenington, S. (1993). Factors modulating preferences of female house mice for males differing in t-complex genotype. Role of t-complex genotype, genetic background, and estrous condition of females. Behavior Genetics, 23, 51–58.

    Article  PubMed  Google Scholar 

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Acknowledgments

SCR is supported by a British Academy Mid-Career Fellowship. JH and KK are supported by the Charles University Research Centre UNCE 204004 and KK is also supported by the Grant GACR P407/12/P819.

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Authors and Affiliations

  1. School of Natural Sciences, University of Stirling, Stirling, FK9 4LA, UK

    S. Craig Roberts

  2. Department of Psychology, University of Groningen, Groningen, The Netherlands

    Kelly D. Cobey

  3. Department of Anthropology, Charles University, Prague, Czech Republic

    Kateřina Klapilová

  4. Department of Zoology, Charles University, Prague, Czech Republic

    Jan Havlíček

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  1. S. Craig Roberts
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  2. Kelly D. Cobey
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  3. Kateřina Klapilová
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  4. Jan Havlíček
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Correspondence to S. Craig Roberts.

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Roberts, S.C., Cobey, K.D., Klapilová, K. et al. An Evolutionary Approach Offers a Fresh Perspective on the Relationship Between Oral Contraception and Sexual Desire. Arch Sex Behav 42, 1369–1375 (2013). https://doi.org/10.1007/s10508-013-0126-9

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Keywords

  • Major Histocompatibility Complex
  • Oral Contraceptive
  • Sexual Desire
  • Hormonal Contraception
  • Major Histocompatibility Complex Allele