Abstract
Many studies have reported higher rates of suicide attempts among sexual minority individuals compared with their heterosexual counterparts. For suicides, however, it has been argued that there is no sexual orientation risk difference, based on the results of psychological autopsy studies. The purpose of this article was to clarify the reasons for the seemingly discrepant findings for suicide attempts and suicides. First, we reviewed studies that investigated if the increased suicide attempt risk of sexual minorities resulted from biased self-reports or less rigorous assessments of suicide attempts. Second, we reanalyzed the only two available case–control autopsy studies and challenge their original “no difference” conclusion by pointing out problems with the interpretation of significance tests and by applying Bayesian statistics and meta-analytical procedures. Third, we reviewed register based and clinical studies on the association of suicides and sexual orientation. We conclude that studies of both suicide attempts and suicides do, in fact, point to an increased suicide risk among sexual minorities, thus solving the discrepancy. We also discuss methodological challenges inherent in research on sexual minorities and potential ethical issues. The arguments in this article are necessary to judge the weight of the evidence and how the evidence might be translated into practice.
Similar content being viewed by others
Notes
Many of the cited studies in this paper would not have been located via a systematic literature search, basically because “homosexuality” or related terms (sexual orientation, bisexuality, gay, lesbian, men who have sex with men etc.) do not appear in the title or the abstract (e.g., Beskow, 1979; Motto, Heilbron, & Juster, 1985; Qin, Agerbo, & Mortensen, 2003; Rothberg, Fagan, & Shaw, 1990).
Fisher’s exact test has been reported to be unnecessarily conservative for the case of two independent binomial distributions (e.g., Lyderson, Fagerland, & Laake, 2009). The application of more powerful tests, such as Barnard’s unconditional test, the mid-p Value, or the Fisher-Boschloo test nearly always produce statistically significant group differences in the Renaud et al. (2010) study (one-sided or two-sided testing), and in most cases of the Shaffer et al. (1995) study for the one-sided tests. Due to limited space, we provided this information online (Footnote 3).
Information can be obtained upon request from the authors. The original submission was accompanied with an additional file that included the R- and BUGS-codes, results for unconditional tests, and further information. It can be retrieved from http://www.pmu.ac.at/de/1367.htm, http://www.youth-suicide.com/, or from http://people.ucalgary.ca/~ramsay/adolescent-gay-lesbian-suicide-risk.htm. The latter webpage includes an in depth analysis of the statistical problems that we address in this article.
References
Alaska Injury Prevention Center. (2007). Alaska suicide follow-back study. Final report study period September 1, 2003 to August 31, 2006. Retrieved from http://www.hss.state.ak.us/suicideprevention/pdfs_sspc/sspcfollowback2-07.pdf.
Australian Government Department of Health and Ageing. (2008). Research and evidence in suicide prevention. Retrieved from http://www.livingisforeveryone.com.au/uploads/docs/LIFE-research-web.pdf.
Bagley, C., & Tremblay, P. (1997). Suicidal behaviors in homosexual and bisexual males. Crisis, 18, 24–34.
Bagley, C., & Tremblay, P. (2000). Elevated rates of suicidal behavior in gay, lesbian, and bisexual youth. Crisis, 21, 111–117.
Balkin, R. S., & Sheperis, C. J. (2011). Evaluating and reporting statistical power in counseling research. Journal of Counseling & Development, 9, 268–272.
Beskow, J. (1979). Suicide in mental disorder in Swedish men. Acta Psychiatrica Scandinavica, 277(Suppl.), 1–138.
Bolton, S. L., & Sareen, J. (2011). Sexual orientation and its relation to mental disorders and suicide attempts: Findings from a nationally representative sample. Canadian Journal of Psychiatry, 56, 35–43.
Bortz, J. (1993). Statistik für Sozialwissenschafter. Berlin: Springer.
Brennan, D. J., Ross, L. E., Dobinson, C., Veldhuizen, S., & Steele, L. S. (2010). Men’s sexual orientation and health in Canada. Canadian Journal of Public Health, 101, 255–258.
British Columbia Child Death Review Unit & BC Coroner Service. (2008). A five-year retrospective review of child and youth suicide in B.C. Retrieved from http://www.pssg.gov.bc.ca/coroners/child-death-review/docs/cdru-suicidereportfull.pdf.
Cass, V. C. (1979). Homosexual identity formation: A theoretical model. Journal of Homosexuality, 4, 219–235.
Catalan, J., Harding, R., Sibley, E., Clucas, C., Croome, N., & Sherr, L. (2011). HIV infection and mental health: Suicidal behavior—Systematic review. Psychology, Health & Medicine, 16, 588–611.
Centers of Disease Control (CDC). (1991). Pilot study of a household survey to determine HIV seroprevalence. Morbidity and Mortality Weekly Report, 40, 1–5.
Chan, A. W., & Altman, D. G. (2005). Epidemiology and reporting of randomised trials published in PubMed journals. Lancet, 365, 1159–1162.
Chandra, A., Mosher, W. D., Copen, C., & Sionean, C. (2011, June 10). Sexual behavior, sexual attraction, and sexual identity in the United States: Data from the 2006–2008 National Survey of Family Growth. National health statistics reports; no 36. Hyattsville, MD: National Center for Health Statistics. Retrieved from www.cdc.gov/nchs/data/nhsr/nhsr036.pdf.
Cochran, S. D., & Mays, V. M. (2011). Sexual orientation and mortality among US men aged 17 to 59 years: Results from the National Health and Nutrition Examination Survey III. American Journal of Public Health, 101, 1133–1138.
D’Augelli, A. R., Grossman, A. H., Salter, N. P., Vasey, J. J., Starks, M. T., & Sinclair, K. O. (2005). Predicting the suicide attempts of lesbian, gay, and bisexual youth. Suicide and Life-Threatening Behavior, 35, 646–660.
D’Augelli, A. R., Hershberger, S. L., & Pilkington, N. W. (1998). Lesbian, gay, and bisexual youths and their families: Disclosure of sexual orientation and its consequences. American Journal of Orthopsychiatry, 68, 361–371.
D’Augelli, A. R., Hershberger, S. L., & Pilkington, N. W. (2001). Suicidality patterns and sexual orientation-related factors among lesbian, gay, and bisexual youths. Suicide and Life-Threatening Behavior, 31, 250–264.
Dorais, M., & Lajeunesse, S. L. (2004). Dead boys can’t dance: Sexual orientation, masculinity and suicide (P. Tremblay, Trans.). Montreal: McGill-Queens University Press.
European Commission. (2008, July). Discrimination in the European Union: Perceptions, experiences and attitudes. Special Eurobarometer 296. Retrieved from http://ec.europa.eu/public_opinion/archives/ebs/ebs_296_en.pdf.
Faul, F., Erdfelder, E., Lang, A.-G., & Buchner, A. (2007). G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39, 175–191.
Fox, R. C. (1995). Lesbian, gay, and bisexual identities over the lifespan: Psychological perspectives. In A. R. D’Augelli & C. P. Patterson (Eds.), Lesbian, gay, and bisexual identities over the lifespan: Psychological perspectives (pp. 48–86). New York: Oxford University Press.
Gratz, K. L. (2006). Risk factors for deliberate self-harm among female college students: The role and interaction of childhood maltreatment, emotional inexpressivity, and affect intensity/reactivity. American Journal of Orthopsychiatry, 76, 238–250.
Haas, A. P., Eliason, M., Mays, V. M., Mathy, R. M., Cochran, S. D., & D’Augelli, A. R.,… Clayton, P. J. (2011). Suicide and suicide risk in lesbian, gay, bisexual, and transgender populations: Review and recommendation. Journal of Homosexuality, 58, 10–51.
Harris, E. C., & Barraclough, B. (1997). Suicide as an outcome for mental disorders. A meta-analysis. British Journal of Psychiatry, 170, 205–228.
Hatzenbuehler, M. (2009). How does sexual minority stigma “get under the skin”? A psychological mediation framework. Psychological Bulletin, 135, 707–730.
Hong, J. S., Espelage, D. L., & Krall, M. J. (2011). Understanding suicide among sexual minority youth in America: An ecological systems analysis. Journal of Adolescence, 34, 885–894.
Irish Departments of Public Health. (2001). Suicide in Ireland. A national study. Retrieved from http://www.nosp.ie/suicide_in_ireland.pdf.
Jeffreys, H. (1961). Theory of probability. Oxford: Oxford University Press.
Jiang, Y., Perry, D. K., & Hesser, J. E. (2010). Adolescent suicide and health risk behaviors: Rhode Island’s 2007 Youth Risk Behavior Survey. American Journal of Preventive Medicine, 38, 551–555.
Kann, L., Olsen, E. O., McManus, T., Kinchen, S., Chyen, D., Harris, W. A.,… Centers for Disease Control and Prevention (CDC). (2011). Sexual identity, sex of sexual contacts, and health-risk behaviors among students in grades 9-12—Youth risk behavior surveillance, selected sites, United States, 2001–2009. MMWR, 60, 1–133. Retrieved from http://www.cdc.gov/mmwr/pdf/ss/ss6007.pdf.
Kass, R. E., & Raftery, A. E. (1995). Bayes factors. Journal of the American Statistical Association, 90, 377–395.
King, M., Semlyen, J., Tai, S. S., Killaspy, H., Osborn, D., Popelyuk, D., & Nazareth, I. (2008). A systematic review of mental disorder, suicide, and deliberate self harm in lesbian, gay and bisexual people. BMC Psychiatry, 8, 70. doi:10.1186/1471-244X-8-70.
Kisch, J., Leino, E. V., & Silverman, M. M. (2005). Aspects of suicidal behavior, depression, and treatment in college students: Results from the spring 2000 National College Health Assessment Survey. Suicide and Life-Threatening Behavior, 35, 3–13.
Kruschke, J. K. (2011). Bayesian assessment of the null values via parameter estimation and model comparison. Perspectives on Psychological Science, 6, 299–312.
Lee, M. D., & Wagenmakers, E. J. (2010, August 23). A course in Bayesian graphical modeling for cognitive science. Retrieved from http://www.ejwagenmakers.com/BayesCourse/BayesBookWeb.pdf.
Lewis, N. M. (2009). Mental health in sexual minorities: Recent indicators, trends, and their relationships to place in North America and Europe. Health and Place, 15, 1029–1045.
Lombardi, G., Mondaini, N., Iazzetta, P., Macchiarella, A., & Del Popolo, G. (2008). Sexuality in patients with spinal cord injuries due to attempted suicide. Spinal Cord, 46, 53–57.
Lunn, D. J., Thomas, A., Best, N., & Spiegelhalter, D. (2000). WinBUGS—A Bayesian modelling framework: Concepts, structure, and extensibility. Statistics and Computing, 10, 325–337.
Lydersen, S., Fagerland, M. W., & Laake, P. (2009). Recommended tests for association in 2 × 2 tables. Statistics in Medicine, 28, 1159–1175.
Lynch, S. M. (2007). Introduction to applied Bayesian statistics and estimation for social scientists. Berlin: Springer.
Marshal, M. P., Dietz, L. J., Friedman, M. S., Stall, R., Smith, H. A., McGinley, J., Thoma, B. C.,… Brent, D. A. (2011). Suicidality and depression disparities between sexual minority and heterosexual youth: A meta-analytic review. Journal of Adolescent Health, 49, 115–123.
Martin, R. L., Cloninger, C. R., Guze, S. B., & Clayton, P. J. (1985). Mortality in a follow-up of 500 psychiatric outpatients. II. Cause-specific mortality. Archives of General Psychiatry, 42, 58–66.
Martin, A. D., & Hetrick, E. S. (1988). The stigmatization of the gay and lesbian adolescent. Journal of Homosexuality, 15, 163–183.
Mathy, R. M., Cochran, S. D., Olsen, J., & Mays, V. M. (2009). The association between relationship markers of sexual orientation and suicide: Denmark, 1990–2001. Social Psychiatry and Psychiatric Epidemiology, 46, 111–117.
McCabe, S. E., Hughes, T. L., Bostwick, W., Morales, M., & Boyd, C. J. (2012). Measurement of sexual identity in surveys: Implications for substance abuse research. Archives of Sexual Behavior, 41, 649–657.
McDaniel, J. S., Purcell, D., & D’Augelli, A. R. (2001). The relationship between sexual orientation and risk for suicide: Research findings and future directions for research and prevention. Suicide and Life-Threatening Behavior, 31, 84–105.
Meehan, P. J., Lamb, J. A., Saltzman, L. E., & O’Carroll, W. O. (1992). Attempted suicide among young adults: Progress toward a meaningful estimate of prevalence. American Journal of Psychiatry, 149, 41–49.
Meyer, I. H. (2003). Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: Conceptual issues and research evidence. Psychological Bulletin, 129, 674–697.
Meyer, I. H., & Wilson, P. A. (2009). Sampling lesbian, gay, and bisexual populations. Journal of Counseling Psychology, 56, 23–31.
Miller, D. N., & Eckert, T. L. (2009). Youth suicidal behavior: An introduction and overview. School Psychology Review, 38, 153–167.
Mitterauer, B. (1981). The suicidal axis syndrome. A medico-biological study of the estimation of suicide-proneness. Wiener Medizinische Wochenschrift, 68(Suppl.), 1–28.
Motto, J. A., Heilbron, D. C., & Juster, R. P. (1985). Development of a clinical instrument to estimate suicide risk. American Journal of Psychiatry, 142, 680–686.
Muehrer, P. (1995). Suicide and sexual orientation: A critical summary of recent research and directions for future research. Suicide and Life-Threatening Behavior, 25, 72–81.
Murphy, H. E. (2007). Suicide risk among gay, lesbian and bisexual college youth. Unpublished doctoral dissertation, University of Washington. Retrieved from http://hdl.handle.net/1773/7522.
Mustanski, B. S., Garofalo, R., & Emerson, E. M. (2010). Mental health disorders, psychological distress, and suicidality in a diverse sample of lesbian, gay, bisexual, and transgender youths. American Journal of Public Health, 100, 2426–2432.
Newcomb, M. E., & Mustanski, B. (2010). Internalized homophobia and internalizing mental health problems: A meta-analytic review. Clinical Psychology Review, 30, 1019–1029.
Newcomb, M. E., & Mustanski, B. (2011). Moderators of the relationship between internalized homophobia and risky sexual behavior in men who have sex with men: A meta-analysis. Archives of Sexual Behavior, 40, 189–199.
O’Connor, R. C., Rasmussen, S., Miles, J., & Hawton, K. (2009). Self-harm in adolescents: Self-report survey in schools in Scotland. British Journal of Psychiatry, 194, 68–72.
Olshen, E., McVeigh, K. H., Wunsch-Hitzig, R. A., & Rickert, V. I. (2007). Dating violence, sexual assault, and suicide attempts among urban teenagers. Archives of Pediatrics and Adolescent Medicine, 161, 539–545.
Owens, D., Wood, C., Greenwood, D. C., Hughes, T., & Dennis, M. (2005). Mortality and suicide after non-fatal self-poisoning: 16-year outcome study. British Journal of Psychiatry, 187, 470–475.
Pachankis, P. E. (2007). The psychological implications of concealing a stigma: A cognitive-affective-behavioral model. Psychological Bulletin, 133, 328–345.
Plöderl, M., & Fartacek, R. (2005). Suicidality and associated risk factors among lesbian, gay, and bisexual compared to heterosexual Austrian adults. Suicide and Life-Threatening Behavior, 35, 661–670.
Plöderl, M., & Fartacek, R. (2009). Childhood gender nonconformity and childhood harassment as predictors of suicidality among gay, lesbian, bisexual, and heterosexual Austrians. Archives of Sexual Behavior, 38, 400–410.
Plöderl, M., Kralovec, K., & Fartacek, R. (2010). The relation between sexual orientation and suicide attempts in Austria. Archives of Sexual Behavior, 39, 1403–1414.
Plöderl, M., Kralovec, K., Yazdi, K., & Fartacek, R. (2011). A closer look at self-reported suicide attempts: False positives and false negatives. Suicide and Life-Threatening Behavior, 41, 1–5.
Plöderl, M., Sauer, J., & Fartacek, R. (2006). Suizidalität und psychische Gesundheit von homo- und bisexuellen Männern und Frauen. Eine metaanalytische Zusammenfassung internationaler Zufallsstichproben [Suicidality and mental health of homosexual and bisexual men and women. A meta-analysis of international probability samples]. Verhaltenstherapie und psychosoziale Praxis, 117, 4–10.
Qin, P., Agerbo, E., & Mortensen, P. B. (2003). Suicide risk in relation to socioeconomic, demographic, psychiatric, and familial factors: A national register-based study of all suicides in Denmark, 1981–1997. American Journal of Psychiatry, 160, 765–772.
R Development Core Team. (2010). R: A language and environment for statistical computing [Software]. Vienna, Austria. Available from http://www.r-project.org/.
Radkowski, M., & Siegel, L. J. (1997). The gay adolescent: Stressors, adaptions, and psychosocial interventions. Clinical Psychology Review, 17, 191–216.
Ramsay, R., & Tremblay, P. (2012a). Gay, lesbian, bisexual & transgender “attempted suicide” incidences/risks. Suicidality studies from 1970 to 2012. Retrieved from http://people.ucalgary.ca/~ramsay/attempted-suicide-gay-lesbian-all-studies.htm.
Ramsay, R., & Tremblay, P. (2012b). Homosexually oriented people are at greater risk for more serious suicidal behaviors. Retrieved from http://people.ucalgary.ca/~ramsay/gay-more-risk-suicide.htm.
Reis, B., & Saewyc, E. (1999, May). Eighty-three-thousand youth: Selected findings of eight population based studies as they pertain to anti-gay harassment and the safety and well-being of sexual minority students. The Safe Schools Coalition of Washington. Retrieved from http://www.safeschoolscoalition.org/83000youth.pdf.
Renaud, J., Berlim, M. T., Begolli, M., McGirr, A., & Turecki, G. (2010). Sexual orientation and gender identity in youth suicide victims: An exploratory study. Canadian Journal of Psychiatry, 55, 29–34.
Rich, C. L., Fowler, R. C., Young, D., & Blenkush, M. (1986). San Diego suicide study: Comparison of gay to straight males. Suicide and Life-Threatening Behavior, 16, 448–457.
Riggle, E. D., Rostosky, S. S., & Horne, S. G. (2010). Psychological distress, well-being, and legal recognition in same-sex couple relationships. Journal of Family Psychology, 24, 82–86.
Rothberg, J. M., Fagan, J., & Shaw, J. (1990). Suicide in United States Army personnel, 1985–1986. Military Medicine, 155, 452–456.
Russell, S. T. (2003). Sexual minority youth and suicide risk. American Behavioral Scientist, 46, 1241–1257.
Savin-Williams, R. C. (2001). Suicide attempts among sexual-minority youths: Population and measurement issues. Journal of Consulting and Clinical Psychology, 69, 983–991.
Savin-Williams, R. C. (2008). Then and now: Recruitment, definition, diversity, and positive attributes of same-sex populations. Developmental Psychology, 44, 135–138.
Savin-Williams, R. C., & Ream, G. L. (2003). Suicide attempts among sexual-minority male youth. Journal of Clinical Child and Adolescent Psychology, 32, 509–522.
Sedlmeier, P., & Gigerenzer, G. (1989). Do studies of statistical power have an effect on the power of studies? Psychological Bulletin, 105, 309–316.
Shaffer, D., Fisher, P., Hicks, R. H., Parides, M., & Gould, M. (1995). Sexual orientation in adolescents who commit suicide. Suicide and Life-Threatening Behavior, 25, 64–71.
Silverman, M. M., Berman, A. L., Sanddal, N. D., O’Carroll, P. W., & Joiner, T. E. (2007). Rebuilding the tower of Babel: A revised nomenclature for the study of suicide and suicidal behaviors part 2: Suicide-related ideations, communications, and behaviors. Suicide and Life-Threatening Behavior, 37, 264–277.
Steele, L. S., Ross, L. E., Dobinson, C., Veldhuizen, S., & Tinmouth, J. M. (2009). Women’s sexual orientation and health: Results from a Canadian population-based survey. Women and Health, 49, 353–367.
Subbiah, M., & Srinivasan, M. R. (2008). Classification of 2 × 2 sparse data sets with zero cells. Statistics and Probability Letters, 78, 3212–3215.
Sweeting, M. J., Sutton, A. J., & Lambert, P. C. (2004). What to add to nothing? Use and avoidance of continuity corrections in meta-analysis of sparse data. Statistics in Medicine, 23, 1351–1375.
Tian, L., Cai, T., Pfeffer, M. A., Piankov, N., Cremieux, P. Y., & Wei, L. J. (2009). Exact and efficient inference procedure for meta-analysis and its application to the analysis of independent 2 × 2 tables with all available data but without artificial continuity correction. Biostatistics, 10, 275–281.
Tremblay, P., Plöderl, M., & Ramsay, R. (2012). Adolescent gay/lesbian suicide risk. An expanded homosexuality factor in adolescent suicide. Retrieved from http://people.ucalgary.ca/~ramsay/adolescent-gay-lesbian-suicide-risk.htm.
Tremblay, P., & Ramsay, R. (2000, September). Orientations homosexuelles ou bisexuelles chez les jeunes présentant des problèmes suicidaires: recherche, problématique et propositions. Le Vis-à-Vie, 10, 5–8. Retrieved from http://web.archive.org/web/20071222142530/www.aqps.info/docs/vav/v10/v10n2-02.html.
Villarroel, M. A., Turner, C. F., Eggleston, E., Al-Tayyib, A., Rogers, S. M., Roman, A. M.,… Gordek, H. (2006). Same-gender sex in the United States. Public Opinion Quarterly, 70, 166–196.
Wagenmakers, E.-J. (2007). A practical solution to the pervasive problems of p values. Psychonomic Bulletin & Review, 14, 779–804.
Wagenmakers, E.-J., Wetzels, R., Borsboom, D., & van der Maas, H. L. J. (2011). Why psychologists must change the way they analyze their data: The case of psi. Journal of Personality and Social Psychology, 100, 426–432.
Wasserman, D., & Wasserman, C. (Eds.). (2009). Oxford textbook of suicidology and suicide prevention: A global perspective. New York: Oxford University Press.
Weyrauch, K. F., Roy-Byrne, P., Katon, W., & Wilson, L. (2001). Stressful life events and impulsiveness in failed suicide. Suicide and Life-Threatening Behavior, 31, 311–319.
Whitehead, N. E. (2009, April 18). Homosexuality and mental health problems. Retrieved from http://narth.com/2009/04/homosexuality-and-mental-health-problems/.
Whitlock, J., & Knox, K. L. (2007). The relationship between self-injurious behavior and suicide in a young adult population. Archives of Pediatrics and Adolescent Medicine, 161, 634–640.
Wichstrøm, L. (2009). Predictors of non-suicidal self-injury versus attempted suicide: Similar or different? Archives of Suicide Research, 13, 105–122.
Wichstrøm, L., & Hegna, K. (2003). Sexual orientation and suicide attempt: A longitudinal study of the general Norwegian population. Journal of Abnormal Psychology, 112, 144–151.
Wortzel, H. S., Gutierrez, P. M., Homaifar, B. Y., Breshears, R. E., & Harwood, J. E. (2010). Surrogate endpoints in suicide research. Suicide and Life-Threatening Behavior, 40, 500–505.
Acknowledgments
We thank Lu Tian, Simon Jackman, and Antonio Martín-Andrés for helping us with statistical issues and we also thank Anthony D’Augelli for his feedback on a draft of the article.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Plöderl, M., Wagenmakers, EJ., Tremblay, P. et al. Suicide Risk and Sexual Orientation: A Critical Review. Arch Sex Behav 42, 715–727 (2013). https://doi.org/10.1007/s10508-012-0056-y
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10508-012-0056-y