Monozygotic Twins Concordant for Female-to-Male Transsexualism: A Case Report
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Transsexualism is a rare phenotype with an estimated frequency varying between 1 in 10,000 up to 1 in 100,000 in male-to-female transsexualism (MTF) and 1 in 30,000 up to 1 in 400,000 in female-to-male transsexualism (FTM) (Cohen-Kettenis & Gooren, 1999). Various explanations have been suggested ranging from biological to psychosocial factors (Coates, 1990; Cohen-Kettenis & Gooren, 1999; Zucker & Bradley, 1995). Emerging evidence supports brain morphological, physical, and genetic differences in transsexual persons (Bosinski et al., 1997; Henningson et al., 2005; Kruiver et al., 2000; van Goozen, Slabbekoorn, Gooren, Sanders, & Cohen-Kettenis, 2002; Zhou, Hofman, Gooren, & Swaab, 1995). Nevertheless, little data exist supporting any single hypothesis. A few monozygotic (MZ) FTM and MTF twin pairs, concordant or discordant for transsexualism, have been reported (Segal, 2006). However, only a single MZ concordant FTM twin pair has been published (Sadeghi & Fakhrai, 2000). We report the...
KeywordsTwin Pair Transsexualism Gender Identity Disorder Twin Sister Sexual Identity Development
- Anchersen, P. (1956). Problems of transvestism. Acta Psychiatrica Neurologica Scandinavica, 106(suppl.), 249–256.Google Scholar
- Diamond, M., & Hawk, S. T. (2004, August). Concordance for gender identity disorder among monozygotic and dizygotic twin pairs. Paper presented at the meeting of the American Psychological Association, Honolulu, HI.Google Scholar
- Hyde, C., & Kenna, J. C. (1977). A male MZ twin pair, concordant for transsexualism, discordant for schizophrenia. Acta Psychologica Scandinavica, 56, 265–275.Google Scholar
- Zucker, K. J., & Bradley, S. J. (1995). Gender identity disorder and psychosexual problems in children and adolescents. New York: Guilford Press.Google Scholar