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Current perspectives and difficulties in the design of acaricides and repellents from plant-derived compounds for tick control

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Abstract

Ticks and tick-borne diseases have gained increasing attention in recent years due to their impact on public health and significant losses in livestock production. The use of synthetic compounds for tick control is becoming problematic, mainly due to the resistance to commercially available products as well as their toxicity. Therefore, new alternative control methods are required. For this purpose, plant-derived extracts may be considered as effective repellents and/or acaricides. The present literature review focuses on studies evaluating the acaricidal and repellent activity of plant-derived extracts and plant secondary metabolites. We also noted recent advances in protein-ligand-docking simulation to examine the possible toxic effect of natural chemical compounds on ticks. In conclusion, plant-derived repellents/acaricides can be effective against ticks, especially in rural areas and livestock farms.

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Acknowledgements

This research was funded by Higher Education Commission (HEC) Pakistan’s National Research Program for Universities (NRPU), grant number 14905.

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Conceptualization NM, AN, AK, writing—original draft preparation NM, EMM, RCB, AK, JED, writing—review and editing IA, NN, ZZ, JK, SN. All authors have read and agreed to the published version of the manuscript.

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Correspondence to Adil Khan or Zbigniew Zając.

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Malak, N., Niaz, S., Miranda-Miranda, E. et al. Current perspectives and difficulties in the design of acaricides and repellents from plant-derived compounds for tick control. Exp Appl Acarol (2024). https://doi.org/10.1007/s10493-024-00901-y

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