Potentially Inappropriate Antidepressant Prescriptions Among Older Adults in Office-Based Outpatient Settings: National Trends from 2002 to 2012

  • Taeho Greg Rhee
  • Jon C. Schommer
  • Benjamin D. Capistrant
  • Ronald L. Hadsall
  • Donald L. Uden
Original Article

Abstract

Using data from 2002 to 2012 National Ambulatory Medical Care Survey, we estimated that the prevalence of overall antidepressant prescriptions increased almost twofold from 5.2% in 2002 to 10.1% in 2012 in office-based outpatient visits made by older adults. In addition, older adults were exposed to the risk of potentially avoidable adverse drug events in approximately one in ten antidepressant-related visits, or 2.2 million visits annually. Amitriptyline and doxepin were the two most frequent disease-independent potentially inappropriate antidepressants. Racial/ethnic minorities, and Medicaid beneficiaries had higher odds of potentially inappropriate antidepressant prescriptions (P < 0.05). Efforts to minimize potentially inappropriate antidepressant prescriptions are needed.

Keywords

Antidepressant Office-based care Older adults Beers Criteria Inappropriate use Prescribing pattern 

Supplementary material

10488_2017_817_MOESM1_ESM.doc (118 kb)
Supplementary material 1 (DOC 117 KB)

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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  1. 1.Section of Geriatrics, Department of Internal Medicine, School of MedicineYale UniversityNew HavenUSA
  2. 2.Department of Pharmaceutical Care and Health SystemsUniversity of Minnesota College of PharmacyMinneapolisUSA
  3. 3.Division of Epidemiology and Community HealthUniversity of Minnesota School of Public HealthMinneapolisUSA

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