The Effect of Disclosure of PrEP Use on Adherence Among African Young Women in an Open-Label PrEP Study: Findings from HPTN 082

Table 4 Disclosure of PrEP use by month three and housing with parents at month three on PrEP adherence at months three and six

	Increase in DBS TFV-DP concentration
		Month three adherence^a				Month six adherence^a
	Average (95% CI)	fmol/punch (95% CI)	T test	P value	Average (95% CI)	fmol/punch (95% CI)	T test	P value
Disclosed to parents and live with parents (n = 84)	431 (372, 490)	90 (− 20, 199)	1.60	0.11	308 (238, 379)	50 (− 92, 193)	0.69	0.49
Disclosed to parents but does not live with parents (n = 143)	472 (392, 554)	74 (− 42, 191)	1.26	0.21	461 (344, 578)	159 (6, 312)	2.04	0.04
Did not disclose to parents (n = 108)	397 (308, 485)	Ref			333 (223, 442)	Ref

DBS TFV-DP tenofovir-diphosphate concentrations in dried blood spots, CI confidence interval
^aAdjusted for site and age