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Longitudinal Dyadic Interdependence in Depression Symptoms of Caregivers Living with HIV in Uganda and Their Dependent Children’s Neurodevelopment and Executive Behavior Outcomes

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Abstract

We tested a model of dyadic interdependence in depression symptoms experienced by female caregivers living with HIV in Uganda (n = 288) and behavioral problems of their HIV-infected (n = 92) and perinatally HIV-exposed uninfected (HEU) children (n = 196). Three repeated measures of caregiver depression symptoms and child neurodevelopment and behavioral outcomes were related to their own outcomes at a previous time point (actor effects), and the outcomes of the other member of the dyad (partner effects). Caregiver depression and child behavioral problem were interdependent over the 24 months of observation. Caregiver depression at Tn predicted child’s behavioral problems at Tn+1 (coefficient = 0.1220, SE = 0.0313, p < 0.01); child behavioral problems at Tn predicted maternal depression at Tn+1 (coefficient = 0.0984, SE = 0.0253, p < 0.01). Results suggest the importance of services addressing behavioral needs of affected children and mental health of their mothers.

Resumen

Evaluamos la interdependencia en relaciones diádicas entre síntomas de depresión en mujeres viviendo con VIH en Uganda (n = 288) y medidas de neurodesarollo y comportamiento en sus hijos no infectados pero expuestos a VIH (HEU) (n = 196). Tres mediciones repetidas de síntomas de depresión en mujeres y de neurodesarollo y comportamiento en niños estuvieron relacionadas con sus propios resultados en mediciones anteriores (efecto de actor), y con los resultados del otro miembro de la pareja (efecto de pareja). Síntomas depresivos y problemas conductuales fueron interdependientes durante los 24 meses de observación. Síntomas depresivos en mujeres en Tn predijeron problemas conductuales en el niño en Tn+1 (coeficiente = 0.1220, SE = 0.0313, p < 0.01); problemas conductuales en el niño en Tn predijeron depresión en mujeres en Tn+1 (coeficiente = 0.0984 , SE = 0.0253, p < 0.01). Los resultados sugieren la importancia de servicios que se enfoquen en atender problemas conductuales y de salud mental materna.

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Acknowledgements

We wish to thank the participants and the Global Health Uganda-Tororo team that made this research possible. This research was supported by NIH Grant R01 HD070723.

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Authors and Affiliations

  1. Department of Psychiatry, Michigan State University, 909 Wilson Rd. A322, East Lansing, MI, USA

    Itziar Familiar

  2. Visiting Nurse Service of New York, New York City, NY, USA

    Atreyee Majumder

  3. Departments of Psychiatry and Statistics, Michigan State University, East Lansing, MI, USA

    Alla Sikorskii

  4. Departments of Psychiatry and Neurology, Michigan State University, East Lansing, MI, USA

    Michael Boivin

  5. Department of Psychiatry College of Health Sciences, Makerere University, Kampala, Uganda

    Noeline Nakasujja

  6. Mental Health Department, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA

    Judith Bass

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  1. Itziar Familiar
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Correspondence to Itziar Familiar.

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Familiar, I., Majumder, A., Sikorskii, A. et al. Longitudinal Dyadic Interdependence in Depression Symptoms of Caregivers Living with HIV in Uganda and Their Dependent Children’s Neurodevelopment and Executive Behavior Outcomes. AIDS Behav 25, 3828–3835 (2021). https://doi.org/10.1007/s10461-021-03192-1

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