Skip to main content

Advertisement

Log in

Detecting Depression in People Living with HIV in South Africa: The Factor Structure and Convergent Validity of the South African Depression Scale (SADS)

  • Original Paper
  • Published:
AIDS and Behavior Aims and scope Submit manuscript

Abstract

Screening measures for depression developed in high-income countries have not always demonstrated strong psychometric properties in South Africa and with people living with HIV (PLWH). The present study explored the psychometric properties of the 16-item South African Depression Scale (SADS) comprised of idioms of distress specific to isiXhosa culture in PLWH. The SADS was administered to 137 Xhosa-speaking PLWH who met diagnostic criteria for major depressive disorder (MDD) together with the Hamilton Depression Scale (HAM-D) and the Center for Epidemiological Studies Depression Scale (CES-D). We conducted exploratory factor analysis, correlation, and reliability statistics. Four factors of the SADS emerged: Sadness, lethargy/burdened, anhedonia/withdrawal, and cognitive/somatic. All factors correlated significantly with the HAM-D and CES-D. Internal consistency of the overall measure was high (α = .89). The SADS promises to be a robust measure of depression in isiXhosa-speaking PLWH in South Africa likely due to the inclusion of local idioms of distress.

RESUMEN

Las medidas de detección de la depresión que se desarrollaron en países de altos ingresos no siempre han demostrado fuertes propiedades psicométricas en Sudáfrica y con personas que viven con el VIH (PVVS). El estudio actual exploró las propiedades psicométricas de la Escala de Depresión Sudafricana de 16 preguntas (SADS) compuesta por modismos de angustia específicos de la cultura isiXhosa en PVVS. El SADS se administró a 137 PVVS Xhosa que cumplieron los criterios diagnósticos para el trastorno depresivo mayor (TDM) junto con la Escala de Depresión de Hamilton (HAM-D) y la Escala de Depresión del Centro de Estudios Epidemiológicos (CES-D). Realizamos análisis factorial exploratorio, correlación y estadísticas de fiabilidad. Cuatro factores del SADS emergieron: Tristeza, letargo/agobiado, anhedonia/ abstinencia, y cognitiva/somática. Todos los factores se correlacionaron significativamente con el HAM-D y el CES-D. La consistencia interna de la medida general fue alta (α = .89). El SADS promete ser una medida robusta de depresión en las PVVS que hablan isiXhosa en Sudáfrica, probablemente debido a la inclusión de expresiones idiomáticas locales de angustia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Vos T, Abajobir AA, Abbafati C, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1211–59.

    Article  Google Scholar 

  2. Whiteford HA, Degenhardt L, Rehm J, et al. Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet. 2013;382(9904):1575–86.

    Article  PubMed  Google Scholar 

  3. Herman AA, Stein DJ, Seedat S, Heeringa SG, Moomal H, Williams DR. The South African Stress and Health (SASH) study: 12-month and lifetime prevalence of common mental disorders. S Afr Med J. 2009;99(5):339–44.

    PubMed  PubMed Central  Google Scholar 

  4. Freeman M, Nkomo N, Kafaar Z, Kelly K. Mental disorder in people living with HIV/AIDS in South Africa. S Afr J Psychol. 2008;38(3):489–500.

    Article  Google Scholar 

  5. Zunszain PA, Anacker C, Cattaneo A, Carvalho LA, Pariante CM. Glucocorticoids, cytokines and brain abnormalities in depression. Prog Neuropsychopharmacol Biol Psychiatry. 2011;35(3):722–9.

    Article  CAS  PubMed  Google Scholar 

  6. Schroecksnadel K, Sarcletti M, Winkler C, Mumelter B, Weiss G, Fuchs D, Kemmler G, Zangerle R. Quality of life and immune activation in patients with HIV-infection. Brain Behav Immun. 2008;22(6):881–9.

    Article  CAS  PubMed  Google Scholar 

  7. Peltzer K, Szrek H, Ramlagan S, Leite R, Chao LW. Depression and social functioning among HIV-infected and uninfected persons in South Africa. AIDS Care. 2015;27(1):41–6.

    Article  PubMed  Google Scholar 

  8. Gonzalez JS, Batchelder AW, Psaros C, Safren SA. Depression and HIV/AIDS treatment nonadherence: a review and meta-analysis. J Acquir Immune Defic Syndr. 2011;58(2):181–7.

    Article  PubMed  Google Scholar 

  9. Nakimuli-Mpungu E, Bass JK, Alexandre P, et al. Depression, alcohol use and adherence to antiretroviral therapy in sub-Saharan Africa: a systematic review. AIDS Behav. 2012;16(8):2101–18.

    Article  PubMed  Google Scholar 

  10. Uthman OA, Magidson JF, Safren SA, Nachega JB. Depression and adherence to antiretroviral therapy in low-, middle-and high-income countries: a systematic review and meta-analysis. Curr HIV/AIDS Rep. 2014;11(3):291–307.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Leserman J, Jackson ED, Petitto JM, et al. Progression to AIDS: the effects of stress, depressive symptoms, and social support. Psychosom Med. 1999;61(3):397–406.

    Article  CAS  PubMed  Google Scholar 

  12. Arseniou S, Arvaniti A, Samakouri M. HIV infection and depression. Psychiatry Clin Neurosci. 2014;68(2):96–109.

    Article  PubMed  Google Scholar 

  13. Andersen LS, Grimsrud A, Myer L, Williams DR, Stein DJ, Seedat S. The psychometric properties of the K10 and K6 scales in screening for mood and anxiety disorders in the South African Stress and Health study. Int J Methods Psychiatr Res. 2011;20(4):215–23.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Tsai AC. Reliability and validity of depression assessment among persons with HIV in sub-Saharan Africa: systematic review and meta-analysis. J Acquir Immune Defic Syndr. 2014;66(5):503–11.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Radloff LS. The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1(3):385–401.

    Article  Google Scholar 

  16. Kessler RC, Andrews G, Colpe LJ, et al. Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychol Med. 2002;32(6):959–76.

    Article  CAS  PubMed  Google Scholar 

  17. Patel V, Simunyu E, Gwanzura F, Lewis G, Mann A. The Shona Symptom Questionnaire: the development of an indigenous measure of common mental disorders in Harare. Acta Psychiatr Scand. 1997;95(6):469–75.

    Article  CAS  PubMed  Google Scholar 

  18. Andersen L, Kagee A, O'Cleirigh C, Safren S, Joska J. Understanding the experience and manifestation of depression in people living with HIV/AIDS in South Africa. AIDS Care. 2015;27(1):59–62.

    Article  CAS  PubMed  Google Scholar 

  19. Sheehan DV, Lecrubier Y, Sheehan KH, et al. The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59:34–57.

    Google Scholar 

  20. Hamilton M. A rating scale for depression. J. Neurol Neurosurg Psychiatry. 1960;23:56–62.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Brislin RW. Back-translation for cross-cultural research. J Cross Cult Psychol. 1970;1(3):185–216.

    Article  Google Scholar 

  22. Myer L, Smit J, Roux LL, Parker S, Stein DJ, Seedat S. Common mental disorders among HIV-infected individuals in South Africa: prevalence, predictors, and validation of brief psychiatric rating scales. AIDS Patient Care STDS. 2008;22(2):147–58.

    Article  PubMed  Google Scholar 

  23. Williams JB. Standardizing the Hamilton Depression Rating Scale: past, present, and future. Eur Arch Psychiatry Clin Neurosci. 2001;251(2):6–12.

    Article  Google Scholar 

  24. Gagiano CA, Muller FG, Berk M, Joubert PM, Brown RG, Schall R. Moclobemide twice daily in the treatment of major depressive episode: a double-blind, multicenter comparison with different three times daily dosage schedules. J Clin Psychopharmacol. 1995;15(4):4S–9S.

    Article  CAS  PubMed  Google Scholar 

  25. Gagiano CA, Muller FG, de Kock RF, Schall R. Moclobemide in continuation treatment of major depressive episodes: an open follow-up study over six months. J Clin Psychopharmacol. 1995;15(4):46S–50S.

    Article  CAS  PubMed  Google Scholar 

  26. Kennedy SH, Emsley R. Placebo-controlled trial of agomelatine in the treatment of major depressive disorder. Eur Neuropsychopharmacol. 2006;16(2):93–100.

    Article  CAS  PubMed  Google Scholar 

  27. IBM Corp. Released 2017. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.

  28. R Development Core Team. (2016). R: A language and environment for statistical computing (Version 3.3.2) [Windows]. Retrieved from https://www.R-project.org

  29. Revelle, W. (2018). psych: Procedures for Psychological, Psychometric, and Personality Research. Retrieved from https://CRAN.R-project.org/package=psych

  30. Floyd FJ, Widaman KF. Factor analysis in the development and refinement of clinical assessment instruments. Psychol Assess. 1995;7(3):286–99.

    Article  Google Scholar 

  31. Makhubela MS, Mashegoane S. Validation of the beck depression inventory–II in South Africa: factorial validity and longitudinal measurement invariance in university students. S Afr J Psychol. 2016;46(2):203–17.

    Article  Google Scholar 

  32. Olley BO, Seedat S, Nei DG, Stein DJ. Predictors of major depression in recently diagnosed patients with HIV/AIDS in South Africa. AIDS Patient Care STDS. 2004;18(8):481–7.

    Article  CAS  PubMed  Google Scholar 

  33. Psaros C, Haberer JE, Boum Y, et al. The factor structure and presentation of depression among HIV-positive adults in Uganda. AIDS Behav. 2015;19(1):27–33.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Betancourt TS, Yang F, Bolton P, Normand S. Developing an African youth psycho-social assessment: an application of item response theory. Int J Methods Psychiatr Res. 2014;23(2):142–60.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Emerson JA, Tol W, Caulfield LE, Doocy S. Maternal psychological distress and perceived impact on child feeding practices in South Kivu, DR Congo. Food Nutr Bull. 2017;38(3):319–37.

    Article  PubMed  Google Scholar 

  36. Kalichman SC, Sikkema KJ, Somlai A. Assessing persons with human immunodeficiency virus (HIV) infection using the Beck Depression Inventory: disease processes and other potential confounds. J Pers Assess. 1995;64(1):86–100.

    Article  CAS  PubMed  Google Scholar 

  37. Okello ES, Neema S. Explanatory models and help-seeking behavior: pathways to psychiatric care among patients admitted for depression in Mulago Hospital, Kampala, Uganda. Qual Health Res. 2007;17(1):14–25.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

This project was supported by National Institute of Mental Health (NIMH) Grant R01MH103770 (Safren/O’Cleirigh). Some additional author time was supported by K24DA040489 (Safren), 1P30MH116867 (Safren), and K23DA041901 (Magidson). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Mental Health or the National Institutes of Health.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L. S. Andersen.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Andersen, L.S., Joska, J.A., Magidson, J.F. et al. Detecting Depression in People Living with HIV in South Africa: The Factor Structure and Convergent Validity of the South African Depression Scale (SADS). AIDS Behav 24, 2282–2289 (2020). https://doi.org/10.1007/s10461-020-02787-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10461-020-02787-4

Keywords

PALABRAS CLAVE

Navigation