Abstract
Transgender women experience disproportionate risk of HIV acquisition and transmission. We piloted ‘Sheroes’, a peer-led group-level intervention for transgender women of any HIV status emphasizing empowerment and gender affirmation to reduce HIV risk behaviors and increase social support. Participants (N = 77) were randomized to Sheroes (n = 39) or a time- and attention-matched control (n = 38). Sheroes is 5 weekly group sessions; topics include sexuality, communication, gender transition, and coping skills. Control participants attended 5 weekly group movie sessions. At 6-month follow up, HIV-negative and unknown status Sheroes participants reported reductions in condomless intercourse and improved social support compared to control. Among participants living with HIV, both the control and intervention groups reduced their total number of sex partners; this change was sustained at 6-month follow-up for Sheroes participants but not for control participants relative to baseline. Sheroes was deemed highly feasible and acceptable to participants; findings support preliminary efficacy of Sheroes.
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References
Grant J, Mottet L, Tanis J, Harrison J, Herman J, Keisling M. Injustice at every turn: a report of the National Transgender Discrimination Survey. Washington: National Center for Transgender Equality and National Gay and Lesbian Task Force; 2011.
Ganju D, Saggurti N. Stigma, violence and HIV vulnerability among transgender persons in sex work in Maharashtra, India. Cult Health Sex. 2017;19(8):903–17.
Yi S, Ngin C, Tuot S, Chhoun P, Chhim S, Pal K, et al. HIV prevalence, risky behaviors, and discrimination experiences among transgender women in Cambodia: descriptive findings from a national integrated biological and behavioral survey. BMC Int Health Hum Rights. 2017;17(1):14.
Perez-Brumer AG, Reisner SL, McLean SA, Silva-Santisteban A, Huerta L, Mayer KH, et al. Leveraging social capital: multilevel stigma, associated HIV vulnerabilities, and social resilience strategies among transgender women in Lima, Peru. J Int AIDS Soc. 2017;20(1):1–8.
Salazar LF, Crosby RA, Jones J, Kota K, Hill B, Masyn KE. Contextual, experiential, and behavioral risk factors associated with HIV status: a descriptive analysis of transgender women residing in Atlanta, Georgia. Int J STD AIDS. 2017. https://doi.org/10.1177/0956462416686722.
Garafalo R, Deleon J, Osmer E, Doll M, Harper G. Overlooked, misunderstood, and at-risk: exploring the lives and HIV risk of ethnic minority male-to-female transgender youth. J Adolesc Health. 2006;38(3):230–6.
Baral SD, Poteat T, Stromdahl S, Wirtz AL, Guadamuz TE, Beyrer C. Worldwide burden of HIV in transgender women: a systematic review and meta-analysis. Lancet Infect Dis. 2013;13(3):214–22.
Poteat T, Reisner SL, Radix A. HIV epidemics among transgender women. Curr Opin HIV AIDS. 2014;9(2):168–73.
Parsons JT, Antebi-Gruszka N, Millar BM, Cain D, Gurung S. Syndemic conditions, HIV transmission risk behavior, and transactional sex among transgender women. AIDS Behav. 2018;22:2056–67.
California Department of Health Services. California HIV counseling and testing annual report: January - December 2003. Sacramento: Office of AIDS; 2006.
Herbst J, Jacobs E, Finlayson T, McKleroy V, Neumann M, Crepaz N. Estimating HIV prevalence and risk behaviors of transgender persons in the United States: a systematic review. AIDS Behav. 2008;12(1):1–17.
Denson DJ, Padgett PM, Pitts N, Paz-Bailey G, Bingham T, Carlos JA, et al. Health care use and HIV-related behaviors of Black and Latina transgender women in 3 US metropolitan areas: results from the transgender HIV behavioral survey. J Acquir Immune Defic Syndr. 2017;75(Suppl 3):S268–75.
Nemoto T, Operario D, Keatley J, Han L, Soma T. HIV risk behaviors among male-to-female transgender persons of color in San Francisco. Am J Public Health. 2004;94(7):1193–9.
Operario D, Gamarel KE, Iwamoto M, Suzuki S, Suico S, Darbes L, et al. Couples-focused prevention program to reduce HIV risk among transgender women and their primary male partners: feasibility and promise of the couples HIV intervention program. AIDS Behav. 2017;21(8):2452–63.
Operario D, Nemoto T. HIV in transgender communities: syndemic dynamics and a need for multicomponent interventions. J Acquir Immune Defic Syndr. 2010;55(Suppl 2):S91–3.
Operario D, Nemoto T, Iwamoto M, Moore T. Unprotected sexual behavior and HIV risk in the context of primary partnerships for transgender women. AIDS Behav. 2011;15(3):674–82.
Brennan J, Kuhns LM, Johnson AK, Belzer M, Wilson EC, Garofalo R. Syndemic theory and HIV-related risk among young transgender women: the role of multiple, co-occurring health problems and social marginalization. Am J Public Health. 2012;102(9):1751–7.
Nadal K, Davidoff K, Fujii-Doe W. Transgender women and the sex work industry: roots in systemic, institutional, and interpersonal discrimination. J Trauma Dissociation. 2014;15(2):169–83.
Rodriguez-Madera S, Toro-Alfonso J. Gender as an obstacle in HIV/AIDS prevention: considerations for the development of HIV/AIDS prevention efforts for male-to-female transgenders. Int J Transgenderism. 2005;8(2):113–22.
Operario D, Soma T, Underhill K. Sex work and HIV status among transgender women: systematic review and meta-analysis. J Acquir Immune Defic Syndr. 2008;48(1):97–103.
Wilson E, Garofalo R, Harris DR, Belzer M. Sexual risk taking among transgender male-to-female youths with different partner types. Am J Public Health. 2010;100(8):1500–5.
Wingood GM, DiClemente RJ, Mikhail I, Lang DL, McCree DH, Davies SL, et al. A randomized controlled trial to reduce HIV transmission risk behaviors and sexually transmitted diseases among women living with HIV: the WiLLOW program. JAIDS J Acquir Immune Defic Syndr. 2004;37:S58–67.
Dale SK, Grimes T, Miller L, Ursillo A, Drainoni M-L. “In our stories”: the perspectives of women living with HIV on an evidence-based group intervention. J Health Psychol. 2017;22(8):1035–45.
Sevelius J, Neilands T, Dilworth S, Castro D, Johnson M. Sheroes: feasibility and acceptability of a community-driven, group-level HIV intervention program for transgender women. In: 22nd international AIDS conference. Amsterdam; 2018.
Sevelius J. Gender affirmation: a framework for conceptualizing risk behavior among transgender women of color. Sex Roles. 2013;68(11–12):675–89.
Diaz R, Ayala G, Bein E. Sexual risk as an outcome of social oppression: data from a probability sample of Latino gay men in three US cities. Cult Divers Ethn Minor Psychol. 2004;10(3):255–67.
Major B, O’Brien L. The social psychology of stigma. Annu Rev Psychol. 2005;56:393–421.
Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–81.
Sarason I, Sarason B, Shearin E, Pierce G. A brief measure of social support: practical and theoretical implications. J Soc Pers Relat. 1987;4:497–510.
Eldridge SM, Lancaster GA, Campbell MJ, Thabane L, Hopewell S, Coleman CL, et al. Defining feasibility and pilot studies in preparation for randomised controlled trials: development of a conceptual framework. PLoS ONE. 2016;11:e0150205.
National Center for Complementary and Integrative Health. Pilot studies: common uses and misuses. 2017. https://www.nccihnihgov/grants/whatnccihfunds/pilot_studies. Accessed 18 Dec 2017.
Melendez RM, Pinto R. ‘It’s really a hard life’: love, gender and HIV risk among male-to-female transgender persons. Cult Health Sex. 2007;9(3):233–45.
Acknowledgements
This study was supported by the National Institutes of Health (R34MH102109, PI: Sevelius, J). Formative work for the development of Sheroes was supported by the California HIV/AIDS Research Program Community Collaborative Award (CR10-SF-421; MPIs: Sevelius, J, Bermudez, C). Dr. Johnson’s contribution to this manuscript was supported by NIDA K24DA037034. This study would not have been possible without the generous contributions of the time and energy of our participants as well as the hard work of the implementation staff: Akira Jackson, Enzo Patouhas, Aria Sa’id, Zoe Samudzi, and Vanessa Warri.
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Sevelius, J.M., Neilands, T.B., Dilworth, S. et al. Sheroes: Feasibility and Acceptability of a Community-Driven, Group-Level HIV Intervention Program for Transgender Women. AIDS Behav 24, 1551–1559 (2020). https://doi.org/10.1007/s10461-019-02683-6
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DOI: https://doi.org/10.1007/s10461-019-02683-6