Abstract
An estimated 1.2 million people in the United States are living with HIV. Of those living with HIV, only 40% are engaged in HIV care, 37% are prescribed antiretroviral therapy (ART), and 30% are virally suppressed. Individual-, interpersonal-, and structural-level factors that represent barriers to engagement along the HIV care continuum are important to identify in order to inform priority areas and interventions. 296 adult residents of Rhode Island living with HIV between November 2015 and January 2016 were asked to participate in an observational study (Ryan White Part B Health Resources and Services Administration-funded consumer needs assessment) to identify the multilevel factors associated with engagement in the HIV care continuum outcomes (i.e., being retained in care, being prescribed ART, adhering to ART, and achieving viral suppression—all in the past 12 months). Multivariable logistic regression models were fit to model the four HIV care continuum outcomes. The majority of participants were over age 30 (92.5%), racial/ethnic minorities (67.1%), cisgender men (56.9%), and identified as straight/heterosexual (60.5%). Overall, 95.2% of participants were retained in care in the past 12 months, 93.0% were prescribed ART, 87.1% were currently adherent to ART, and 68.2% were virally suppressed. Factors positively associated with not being retained in HIV care in the past 12 months included having no income and challenges navigating the HIV care system. Being age 18–29 and having a provider who does not know how to treat people with HIV/AIDS were each positively associated with not being prescribed ART. Factors positively associated with not being adherent to ART included being age 18–29 and substance use in the past 12 months. Finally, having private insurance and having a provider who is not trustworthy were each positively associated with not being virally suppressed. Regardless of the fact that many of the individuals living with HIV in this sample are able to achieve an undetectable viral load, challenges with retention in HIV care and ART adherence threaten to undermine the clinical and public health benefits of treatment as prevention. Future longitudinal research conducted to better understand how to boost the effectiveness of treatment as prevention in this population should focus on examining the unique multilevel factors, polymorbidities, and conditions (mostly social determinants of health including housing, socioeconomic position, etc.) associated with suboptimal engagement across the stages of the HIV care continuum.
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References
CDC. Diagnoses of HIV infection in the United States and dependent areas, 2017 HIV surveillance report;29;2018. Available at: http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html.
CDC. Understanding the HIV care continuum; 2017. https://www.cdc.gov/hiv/pdf/library/factsheets/cdc-hiv-care-continuum.pdf.
Cohen SM, Hu X, Sweeney P, Johnson AS, Hall HI. HIV viral suppression among persons with varying levels of engagement in HIV medical care, 19 US jurisdictions. J Acquir Immune Defic Syndr. 2014;67(5):519–27.
Horstmann E, Brown J, Islam F, Buck J, Agins BD. Retaining HIV-infected patients in care: where are we? where do we go from here? Clin Infect Dis. 2010;50(5):752–61.
) RIDOH Division of Preparedness, Response, Infectious Disease and EMS. 2014 Rhode Island HIV/AIDS epidemiologic profile with surrogate data; 2015. http://health.ri.gov/publications/epidemiologicalprofiles/2014HIVAIDSViralHepatitisWithSurrogateData.pdf.
Krieger N. Theories for social epidemiology in the 21st century: an ecosocial perspective. Int J Epidemiol. 2001;30(4):668–77.
Straus MA. Measuring intrafamily conflict and violence: the conflict tactics (ct) scales. J Marriage Fam. 1979;41(1):75–88.
Hawthorne G, Sansoni J, Hayes L, Marosszeky N, Sansoni E. Measuring patient satisfaction with health care treatment using the short assessment of patient satisfaction measure delivered superior and robust satisfaction estimates. J Clin Epidemiol. 2014;67(5):527–37.
Heckman TG, Somlai AM, Peters J, et al. Barriers to care among persons living with HIV/AIDS in urban and rural areas. AIDS Care. 1998;10:365–75.
Mugavero MJ, Westfall AO, Zinski A, et al. Measuring retention in HIV care: the elusive gold standard. J Acquir Immune Defic Syndr. 2012;61(5):574–80.
Kay ES, Batey DS, Mugavero MJ. The HIV treatment cascade and care continuum: updates, goals, and recommendations for the future. AIDS Res Ther. 2016;13(1):35.
Rand CS. “I took the medicine like you told me, doctor”: self-reports of adherence with medical regimens. In: Stone AA, Turkkan JS, Bachrach CA, Jobe JB, Kurtzman HS, Cain VS, editors. The science of self-report: implications for research and practice (Vol 1). Mahwah: Lawrence Erlbaum Associates; 2000. p. 257–76.
CDC. Social determinants of health and selected HIV care outcomes among adults with diagnosed HIV infection in 37 states and the District of Columbia, 2015. HIV Surveill Suppl Rep. 2017;22(4):7.
The Committee on Public Financing and Delivery of HIV Care. HIV/AIDS care in the third decade: opportunities and challenges in the changing epidemic. In: Public financing and delivery of HIV/AIDS care: securing the legacy of Ryan White. Washington: The National Academies Press; 2005. 36–72.
American Psychological Association. HIV/AIDS & socioeconomic status; 2018. http://www.apa.org/pi/ses/resources/publications/factsheet-hiv-aids.pdf.
Bhattacharya J, Goldman D, Sood N. The link between public and private insurance and HIV-related mortality. J Health Econ. 2003;22(6):1105–22.
Goswami ND, Schmitz MM, Sanchez T, et al. Understanding local spatial variation along the care continuum: the potential impact of transportation vulnerability on HIV linkage to care and viral suppression in high-poverty areas, Atlanta, Georgia. J Acquir Immune Defic Syndr. 2016;72(1):65.
Hall HI, Frazier EL, Rhodes P, et al. Differences in human immunodeficiency virus care and treatment among subpopulations in the United States. JAMA Intern Med. 2013;173(14):1337–44.
Hartzler B, Dombrowski JC, Williams JR, et al. Influence of substance use disorders on 2-year HIV care retention in the United States. AIDS Behav. 2018;22(3):742–51.
Polyakova M. Health insurance: choices, changes, and policy challenges. Stanford Institute for Economic Policy Research; 2016. https://siepr.stanford.edu/sites/default/files/publications/PolicyBrief-Sept16.pdf.
Kinsler JJ, Wong MD, Sayles JN, Davis C, Cunningham WE. The effect of perceived stigma from a health care provider on access to care among a low-income HIV-positive population. AIDS Patient Care STDS. 2007;21(8):584–92.
Marshall AS, Brewington KM, Allison KM, Haynes TF, Zaller ND. Measuring HIV-related stigma among healthcare providers: a systematic review. AIDS Care. 2017;29(11):1337–45.
Wagner AC, Hart TA, McShane KE, Margolese S, Girard TA. Health care provider attitudes and beliefs about people living with HIV: initial validation of the health care provider HIV/AIDS Stigma Scale (HPASS). AIDS Behav. 2014;18(12):2397–408.
Whetten K, Reif S, Whetten R, Murphy-McMillan LK. Trauma, mental health, distrust, and stigma among HIV-positive persons: implications for effective care. Psychosom Med. 2008;70(5):531–8.
Greenberg AE, Purcell DW, Gordon CM, Barasky RJ, Del Rio C. Addressing the challenges of the HIV continuum of care in high prevalence cities in the United States. J Acquir Immune Defic Syndr. 2015;69(0 1):S1.
Mugavero MJ, Norton WE, Saag MS. Health care system and policy factors influencing engagement in HIV medical care: piecing together the fragments of a fractured health care delivery system. Clin Infect Dis. 2011;52(suppl_2):S238–46.
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This study was funded by Ryan White Part B Health Resources and Services Administration (HRSA).
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Mimiaga, M.J., August Oddleifson, D., Meersman, S.C. et al. Multilevel Barriers to Engagement in the HIV Care Continuum Among Residents of the State of Rhode Island Living with HIV. AIDS Behav 24, 1133–1150 (2020). https://doi.org/10.1007/s10461-019-02677-4
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DOI: https://doi.org/10.1007/s10461-019-02677-4