AIDS and Behavior

, Volume 21, Issue 12, pp 3287–3298 | Cite as

Acceptability of Daily Use of Free Oral Pre-exposure Prophylaxis (PrEP) Among Transgender Women Sex Workers in Shenyang, China

  • Zixin Wang
  • Joseph T. F. Lau
  • Xueying Yang
  • Yong Cai
  • Danielle L. Gross
  • Tiecheng Ma
  • Yan Liu
Original Paper

Abstract

This study investigated the acceptability of daily use of free oral pre-exposure prophylaxis (PrEP) and associated factors among transgender women sex workers in Shenyang, China, following a briefing on PrEP. A total of 183 HIV negative or sero-status unknown participants completed the cross-sectional survey. The prevalence of acceptability of daily use of free oral PrEP was 61.2%. Adjusting for education level and monthly income, variables on negative attitudes toward PrEP (i.e., having concerns about the side-effects of PrEP) [Adjusted odds ratios (AOR): 0.26], perceived subjective norms (i.e., perceiving support from male partners to take PrEP) (AOR: 2.08), and perceived behavioral control (e.g., perceiving complete control over using PrEP) (AOR: 2.10–16.72) were significantly associated with acceptability of daily use of free oral PrEP. In addition, experiencing violence during sex work, perceived risk of contracting HIV from clients and probable anxiety were also significant. Future PrEP promotion campaigns should consider these factors.

Keywords

Acceptability Pre-exposure prophylaxis Transgender women sex workers Theory of planned behavior China 

Abbreviations

AOR

Adjusted odds ratios

CI

Confidence interval

CRAI

Condomless receptive anal intercourse

EFA

Exploratory factor analysis

FSW

Female sex workers

FTC

Emtricitabine

HIV

Human immunodeficiency virus

MSM

Men who have sex with men

MSW

Male sex workers

NGO

Non-governmental organization

NRP

Non-regular sex partner

OR

Univariate odds ratios

ORm

Multivariate odds ratios

PrEP

Pre-exposure prophylaxis

RP

Regular sex partner

SD

Standard deviation

STD

Sexually transmitted diseases

TDF

Tenofovir disoproxil fumarate

TPB

Theory of planned behavior

WHO

World Health Organization

Notes

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Research Involving Human Participants

All procedures performed in studies involving human participants were in accordance with the ethical standards of the Survey and Behavioural Research Ethics Committee, the Chinese University of Hong Kong and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  • Zixin Wang
    • 1
    • 2
  • Joseph T. F. Lau
    • 1
    • 2
  • Xueying Yang
    • 1
  • Yong Cai
    • 3
  • Danielle L. Gross
    • 1
  • Tiecheng Ma
    • 4
  • Yan Liu
    • 4
  1. 1.Centre for Health Behaviours Research, JC School of Public Health and Primary CareThe Chinese University of Hong KongHong KongChina
  2. 2.Shenzhen Research InstituteThe Chinese University of Hong KongShenzhenChina
  3. 3.Department of Community Health and Family Medicine, School of Public HealthShanghai Jiao Tong UniversityShanghaiChina
  4. 4.Shenyang Consultation Centre of AIDS Aid and Health ServiceShenyangChina

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