AIDS and Behavior

, Volume 22, Issue 6, pp 1965–1971 | Cite as

Physical Activity is Associated with Metabolic Health in Men Living with HIV

  • Cuisle Forde
  • Aisling Loy
  • Siobhan O’Dea
  • Fiona Mulcahy
  • John Gormley
  • Caroline Daly
Original Paper


Metabolic health is a cause for concern among those living with HIV, especially those on antiretroviral therapy. Physical activity (PA) is known to benefit metabolic health, however, few studies have objectively measured PA or investigated the relationship between PA and metabolic health among those living with HIV. In this study, PA and indices of metabolic health among twenty men living with HIV and twenty age matched HIV-negative men were measured. PA was measured using Actigraph accelerometers. Components of the metabolic syndrome and insulin resistance were measured using routine laboratory methods. Men living with HIV were significantly more physically active than HIV-negative men, and were reaching public PA guidelines. Significant inverse correlations between moderate PA and both insulin resistance (ρ −0.847; p < 0.001) and triglycerides (ρ −0.575; p = 0.013) were seen in those living with HIV. Results of this study emphasize the importance of an active lifestyle for those living with HIV.


HIV Physical activity Metabolic syndrome Sedentary behavior 


La salud metabólica es un motivo de preocupación para las personas que viven con el VIH, en concreto para las que siguen tratamiento antirretrovírico. Se ha demostrado que la actividad física (AF) es beneficiosa para la salud metabólica. No obstante, muy pocos estudios han medido de forma objetiva la AF o investigado la relación existente entre la AF y la salud metabólica en personas que viven con el VIH. En este estudio se han medido la AF y los índices de salud metabólica en veinte hombres que viven con el VIH y veinte hombres agrupados por edad no infectados por el VIH. Para la medición de la AF se utilizaron acelerómetros Actigraph. Los componentes del síndrome metabólico y la resistencia a la insulina se midieron mediante métodos de laboratorio habituales. Los hombres que viven con el VIH se mostraron mucho más activos físicamente que los hombres no infectados por el VIH y se aproximaron a las directrices públicas de AF. Se observaron correlaciones inversas significativas entre la AF moderada y la resistencia a la insulina (ρ −0.847; p < 0.001) y los triglicéridos (ρ −0.575; p = 0.013) en personas que viven con el VIH. Los resultados de este estudio hacen hincapié en la importancia de un estilo de vida activo para aquellos que viven con el VIH.



Many thanks to the staff and patients of the GUIDE clinic in Saint James’s Hospital for their participation and support in carrying out this research.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Discipline of PhysiotherapyUniversity of Dublin, Trinity CollegeDublinIreland
  2. 2.Department of CardiologySaint James’s HospitalDublinIreland
  3. 3.Department of Genito Urinary Medicine and Infectious DiseasesSaint James’s HospitalDublinIreland

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