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Social Network Factors as Correlates and Predictors of High Depressive Symptoms Among Black Men Who Have Sex with Men in HPTN 061

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Abstract

Depression is linked to a range of poor HIV-related health outcomes. Minorities and men who have sex with men (MSM), suffer from high rates of depression. The current study examined the relationship between depressive symptoms and social network characteristics among community-recruited Black MSM in HPTN 061 from 6 US cities. A social network inventory was administer at baseline and depression was assessed with the CES-D at baseline, 6, and 12-months. At baseline, which included 1167 HIV negative and 348 HIV positive participants, size of emotional, financial, and medical support networks were significantly associated with fewer depressive symptoms. In longitudinal mixed models, size of emotional, financial, and medical support networks were significantly associated with fewer depressive symptoms as was the number of network members seen weekly. In the multivariate analyses, size of medical appointment network remained statistically significant (aOR 0.89, CI 0.81–0.98). These findings highlight the importance of network support of medical care on depression and suggest the value of support mobilization.

Resumen

Depresión está vinculado a una variedad de resultados de problemas de salud con el VIH. Las minorías y los hombres que tienen sexo con hombres (HSH), sufren de altos índices de depresión. El presente estudio examinó la relación entre síntomas depresivos y características de red social entre reclutó a comunidad negra HSH en HPTN 061 de 6 ciudades de Estados Unidos. Un inventario de la red social fue administrar al inicio del estudio y la depresión se evaluó con el CES-D al inicio, 6 y 12 meses. En línea de base, que incluyó 1167 VIH negativo y 348 VIH positivos los participantes, el tamaño de las redes de apoyo emocional, financiero y médico se asociaron significativamente con menos síntomas depresivos. En modelos mixtos longitudinales, tamaño de las redes de apoyo emocional, financiero y médico se asociaron significativamente con menos síntomas depresivos como el número de miembros de la red visto semanalmente. En el Análisis multivariantes, tamaño de cita médica red permaneció estadísticamente significativa (aOR = 0.89, CI = 0.81-0.98). Estos resultados destacan la importancia del apoyo de la red de atención médica sobre la depresión y sugieren el valor de la movilización de apoyo.

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Funding

HPTN 061 grant support was provided by the National Institute of Allergy and Infectious Disease (NIAID), National Institute on Drug Abuse (NIDA) and National Institute of Mental Health (NIMH): Cooperative Agreements UM1 AI068619, UM1 AI068617, and UM1 AI068613. Additional site funding—Fenway Institute Clinical Research Site (CRS): Harvard University CFAR (P30 AI060354) and CTU for HIV Prevention and Microbicide Research (UM1 AI069480); George Washington University CRS: District of Columbia Developmental CFAR (P30 AI087714); Harlem Prevention Center CRS and NY Blood Center/Union Square CRS: Columbia University CTU (5U01 AI069466) and ARRA funding (3U01 AI069466-03S1); Hope Clinic of the Emory Vaccine Center CRS and The Ponce de Leon Center CRS: Emory University HIV/AIDS CTU (5U01 AI069418), CFAR (P30 AI050409) and CTSA (UL1 RR025008); San Francisco Vaccine and Prevention CRS: ARRA funding (3U01 AI069496-03S1, 3U01 AI069496-03S2); UCLA Vine Street CRS: UCLA Department of Medicine, Division of Infectious Diseases CTU (U01 AI069424). The funder had a role in the design of the study by providing input into the design. The funder did not have a role in the data collection and analysis, decision to publish, or preparation of the manuscript.

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Authors and Affiliations

  1. Department of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health, 737 Hampton House, Baltimore, MD, 21205, USA

    Carl A Latkin

  2. School of Medicine, Columbia University, New York, NY, USA

    Hong Van Tieu

  3. Mervyn M. Dymally School of Nursing, Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA

    Sheldon Fields

  4. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA

    Brett S. Hanscom, Matt Connor & Brett Hanscom

  5. Hubert Department of Global Health, Rollins School of Public Health Division of Infectious Diseases, School of Medicine, Emory University, Atlanta, GA, USA

    Sophia A. Hussen

  6. San Francisco Department of Public Health, San Francisco, CA, USA

    Hyman M Scott

  7. Department of Behavioral & Social Health Sciences and Epidemiology, School of Public Health, Brown University, Providence, RI, USA

    Matthew J Mimiaga

  8. Department of Human Development, State University of New York at Binghamton, Binghamton, NY, USA

    Leo Wilton

  9. Milken Institute School of Public Health, Department of Epidemiology and Biostatistics, George Washington University, Washington, USA

    Manya Magnus

  10. School of Medicine, Johns Hopkins University, Baltimore, MD, USA

    Iris Chen

  11. Laboratory of Infectious Disease Prevention Member, Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY, USA

    Beryl A Koblin

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  1. Carl A Latkin
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  2. Hong Van Tieu
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  4. Brett S. Hanscom
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  8. Hyman M Scott
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  9. Matthew J Mimiaga
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  10. Leo Wilton
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  11. Manya Magnus
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  12. Iris Chen
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  13. Beryl A Koblin
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Corresponding author

Correspondence to Carl A Latkin.

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The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

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Latkin, C., Van Tieu, H., Fields, S. et al. Social Network Factors as Correlates and Predictors of High Depressive Symptoms Among Black Men Who Have Sex with Men in HPTN 061. AIDS Behav 21, 1163–1170 (2017). https://doi.org/10.1007/s10461-016-1493-8

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  • DOI: https://doi.org/10.1007/s10461-016-1493-8

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