Informal Caregiver Characteristics Associated with Viral Load Suppression Among Current or Former Injection Drug Users Living with HIV/AIDS
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Few studies have examined the association between having an informal (unpaid) caregiver and viral suppression among persons living with HIV/AIDS (PLHIV) who are on antiretroviral therapy. The current study examined relationships between caregivers’ individual and social network characteristics and care recipient viral suppression. Baseline data were from the BEACON study caregivers and their HIV seropositive former or current drug using care recipients, of whom 89 % were African American (N = 258 dyads). Using adjusted logistic regression, care recipient’s undetectable viral load was positively associated with caregiver’s limited physical functioning and negatively associated with caregivers having few family members to turn to for problem solving, a greater number of current drug users in their network, and poorer perceptions of the care recipient’s mental health. Results further understandings of interpersonal relationship factors important to PLHIV’s health outcomes, and the need for caregiving relationship-focused intervention to promote viral suppression among PLHIV.
KeywordsHIV/AIDS Viral load and suppression Care recipients Informal caregivers Social networks
This study was supported by Grants R01 DA019413, R01 NR14050-01, and T-32DA007292 from the National Institutes of Health.
Conflict of interest
All authors have no conflicts of interest and the sources of funding for the project include Grants R01 DA019413 and R01 NR14050-01 from the National Institutes of Health.
- 1.Fisher M, Cooper V. HIV and ageing: premature ageing or premature conclusions? Curr Opin Infect Dis. 2012;25(1):1–3.Google Scholar
- 4.Wood E, Hogg RS, Lima VD, et al. Highly active antiretroviral therapy and survival in HIV-infected injection drug users. JAMA. 2008;300:550–4.Google Scholar
- 5.Tucker JS, Burnam MA, Sherbourne CD, Kung FY, Gifford AL. Substance use and mental health correlates of nonadherence to antiretroviral medications in a sample of patients with human immunodeficiency virus infection. Am J Med. 2003;573–80.Google Scholar
- 7.Knowlton AR, Curry A, Hua W, Wissow L. Depression and social context: primary supporter relationship factors associated with depressive symptoms among a disadvantaged population with HIV/AIDS. J Community Psychol. 2009;526–41.Google Scholar
- 18.Arribas JR, Horban A, Gerstoft J, et al. The MONET trial: darunavir/ritonavir with or without nucleoside analogues, for patients with HIV RNA below 50 copies/ml. AIDS. 2010;(2):223–30.Google Scholar
- 19.Lawton MP, Brody EM. Assessment of older people: Self-maintaining and instrumental activities of daily living activities of daily living. Gerontologist. 1969;9:179–86.Google Scholar
- 21.IBM Corporation. IBM SPSS Statistics for Windows, Version 20.0. Armonk, NY: IBM Corporation; 1999.Google Scholar
- 25.Mitchell MM, Robinson AC, Wolff JL, Knowlton AR. Perceived mental health status of injection drug users living with HIV/AIDS: concordance between informal HIV caregivers and care recipient self-reports and associations with caregiving burden and reciprocity. AIDS Behav. 2014;18(1):1103–13.PubMedCentralCrossRefPubMedGoogle Scholar
- 27.Gonzalez JS, Batchelder AW, Psaros C, Safren SA. Depression and HIV/AIDS treatment nonadherence: a review and meta-analysis. J Acq Immu Def Synd. 2011;58(2):181–7.Google Scholar
- 28.Mehta S, Moore RD, Graham NM. Potential factors affecting adherence with HIV therapy. AIDS. 1997;11(14):1665–70.Google Scholar
- 32.Gross R, Bellamy SL, Chapman J, et al. Managed problem solving for antiretroviral therapy adherence. JAMA Intern Med. 2013;173(4):300–6.Google Scholar