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AIDS and Behavior

, Volume 17, Issue 6, pp 2011–2021 | Cite as

Impact of Protein Supplementation and Care and Support on Body Composition and CD4 Count Among HIV-Infected Women Living in Rural India: Results from a Randomized Pilot Clinical Trial

  • Adeline NyamathiEmail author
  • Sanjeev Sinha
  • Kalyan K. Ganguly
  • Padma Ramakrishna
  • P. Suresh
  • Catherine L. Carpenter
Original Paper

Abstract

Body composition in HIV-infected individuals is subject to many influences. We conducted a pilot 6-month randomized trial of 68 women living with AIDS (WLA) from rural India. High protein intervention combined with education and supportive care delivered by HIV-trained village women (activated social health activist [Asha] life [AL]) was compared to standard protein with usual care delivered by village community assistants (usual care [UC]). Measurements included CD4 counts, ART adherence, socio-demographics, disease characteristics (questionnaires); and anthropometry (bioimpedance analyzer). Repeated measures analysis of variance modeled associations. AL significantly gained in BMI, muscle mass, fat mass, ART adherence, and CD4 counts compared to UC, with higher weight and muscle mass gains among ART adherent (≥66 %) participants who had healthier immunity (CD4 ≥450). BMI of WLA improved through high protein supplementation combined with education and supportive care. Future research is needed to determine which intervention aspect was most responsible.

Keywords

Nutrition AIDS in rural women ART Protein Body composition 

Notes

Acknowledgments

Support for this research was provided by Grant MH82662 from the National Institute on Mental Health.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Adeline Nyamathi
    • 1
    Email author
  • Sanjeev Sinha
    • 2
  • Kalyan K. Ganguly
    • 3
  • Padma Ramakrishna
    • 4
  • P. Suresh
    • 4
  • Catherine L. Carpenter
    • 1
    • 5
  1. 1.School of Nursing, University of California at Los AngelesLos AngelesUSA
  2. 2.All India Institute for Medical ResearchNew DelhiIndia
  3. 3.Indian Council for Medical ResearchNew DelhiIndia
  4. 4.NelloreIndia
  5. 5.Center for Human Nutrition, David Geffen School of Medicine at UCLALos AngelesUSA

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