AIDS and Behavior

, Volume 14, Issue 3, pp 469–482 | Cite as

Behavior Change Interventions to Prevent HIV Infection among Women Living in Low and Middle Income Countries: A Systematic Review

  • Sandra I. McCoyEmail author
  • Rugare A. Kangwende
  • Nancy S. Padian
Original Paper


We conducted a systematic review of behavioral change interventions to prevent the sexual transmission of HIV among women and girls living in low- and middle-income countries. PubMed/MEDLINE, Web of Science, the Cochrane Library, and other databases and bibliographies were systematically searched for trials using randomized or quasi-experimental designs to evaluate behavioral interventions with HIV infection as an outcome. We identified 11 analyses for inclusion reporting on eight unique interventions. Interventions varied widely in intensity, duration, and delivery as well as by target population. Only two analyses showed a significant protective effect on HIV incidence among women and only three of ten analyses that measured behavioral outcomes reduced any measure of HIV-related risk behavior. Ongoing research is needed to determine whether behavior change interventions can be incorporated as independent efficacious components in HIV prevention packages for women or simply as complements to biomedical prevention strategies.


HIV/AIDS prevention Behavioral interventions Women Systematic review 



This work was supported by the International Initiative for Impact Evaluation (3ie). We are grateful to Dr. Temina Madon for helpful comments on the manuscript and Dr. Nick Jewell for statistical advice.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Sandra I. McCoy
    • 1
    Email author
  • Rugare A. Kangwende
    • 2
  • Nancy S. Padian
    • 1
    • 3
  1. 1.Women’s Global Health ImperativeRTI InternationalSan FranciscoUSA
  2. 2.Faculty of Health SciencesAfrica UniversityMutareZimbabwe
  3. 3.Department of EpidemiologyUniversity of CaliforniaBerkeleyUSA

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