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Optimal Recall Period and Response Task for Self-Reported HIV Medication Adherence

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Abstract

Self-reported measures of antiretroviral adherence vary greatly in recall time periods and response tasks. To determine which time frame is most accurate, we compared 3-, 7-day, and 1-month self-reports with data from medication event monitoring system (MEMS). To determine which response task is most accurate we compared three different 1-month self-report tasks (frequency, percent, and rating) to MEMS. We analyzed 643 study visits made by 156 participants. Over-reporting (self-report minus MEMS) was significantly less for the 1-month recall period (9%) than for the 3 (17%) or 7-day (14%) periods. Over-reporting was significantly less for the 1-month rating task (3%) than for the 1-month frequency and percent tasks (both 12%). We conclude that 1-month recall periods may be more accurate than 3- or 7-day periods, and that items that ask respondents to rate their adherence may be more accurate than those that ask about frequencies or percents.

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References

  • Apter, A. J., Cheng, J., Small, D., Bennett, I. M., Albert, C., Fein, D. G., et al. (2006). Asthma numeracy skill and health literacy. The Journal of Asthma, 43, 705–710.

    Article  PubMed  Google Scholar 

  • Arnsten, J. H., Demas, P. A., Farzadegan, H., Grant, R. W., Gourevitch, M. N., Chang, C. J., et al. (2001). Antiretroviral therapy adherence and viral suppression in HIV-infected drug users: Comparison of self-report and electronic monitoring. Clinical Infectious Diseases, 33, 1417–1423.

    Article  CAS  PubMed  Google Scholar 

  • Bangsberg, D. R., Hecht, F. M., Charlebois, E. D., Zolopa, A. R., Holodniy, M., Sheiner, L., et al. (2000). Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population. AIDS, 14, 357–366.

    Article  CAS  PubMed  Google Scholar 

  • Bangsberg, D. R., Hecht, F. M., Clague, H., Charlebois, E. D., Ciccarone, D., Chesney, M., et al. (2001). Provider assessment of adherence to HIV antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes, 26, 435–442.

    CAS  PubMed  Google Scholar 

  • Bova, C. A., Fennie, K. P., Knafl, G. J., Dieckhaus, K. D., Watrous, E., & Williams, A. B. (2005). Use of electronic monitoring devices to measure antiretroviral adherence: Practical considerations. AIDS and Behavior, 9, 103–110.

    Article  PubMed  Google Scholar 

  • Chesney, M. A., Ickovics, J., Hecht, F. M., Sikipa, G., & Rabkin, J. (1999). Adherence: A necessity for successful HIV combination therapy. AIDS, 13(Suppl A), S271–S278.

    PubMed  Google Scholar 

  • Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., et al. (2000). Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG adherence instruments. Patient care committee and adherence working group of the outcomes committee of the adult AIDS clinical trials group (AACTG). AIDS Care, 12, 255–266.

    Article  CAS  PubMed  Google Scholar 

  • Cohen, J. (1977). Statistical power analysis for the behavioral sciences. New York: Academic.

    Google Scholar 

  • Deschamps, A. E., Graeve, V. D., Van, W. E, De, S. V., Vandamme, A. M., Van, V. K., et al. (2004). Prevalence and correlates of nonadherence to antiretroviral therapy in a population of HIV patients using Medication Event Monitoring System. AIDS Patient Care STDS, 18, 644–657.

    Google Scholar 

  • Dykema, J., & Schaeffer, N. C. (2000). Events, instruments, and reporting errors. American Sociological Review, 65, 619–629.

    Article  Google Scholar 

  • Estrada, C., Barnes, V., Collins, C., & Byrd, J. C. (1999). Health literacy and numeracy. JAMA, 282, 527.

    Article  CAS  PubMed  Google Scholar 

  • Gaito, J. (1982) Measurement scales and statistics: Resurgence of an old misconception. Psychological Bulletin, 87, 564–567.

    Article  Google Scholar 

  • Gao, X., Nau, D. P., Rosenbluth, S. A., Scott, V., & Woodward, C. (2000). The relationship of disease severity, health beliefs and medication adherence among HIV patients. AIDS Care, 12, 387–398.

    Article  CAS  PubMed  Google Scholar 

  • Gazmararian, J. A., Baker, D. W., Williams, M. V., Parker, R. M., Scott, T. L., Green, D. C., et al. (1999). Health literacy among Medicare enrollees in a managed care organization. JAMA, 281, 545–551.

    Article  CAS  PubMed  Google Scholar 

  • Giordano, T. P., Guzman, D., Clark, R., Charlebois, E. D., & Bangsberg, D. R. (2004). Measuring adherence to antiretroviral therapy in a diverse population using a visual analogue scale. HIV Clinical Trials, 5, 74–79.

    Article  PubMed  Google Scholar 

  • Golbeck, A. L., Ahlers-Schmidt, C. R., Paschal, A. M., & Dismuke, S. E. (2005). A definition and operational framework for health numeracy. American Journal of Prevntive Medicine, 29, 375–376.

    Article  Google Scholar 

  • Grymonpre, R. E., Didur, C. D., Montgomery, P. R., & Sitar, D. S. (1998). Pill count, self-report, and pharmacy claims data to measure medication adherence in the elderly. The Annals of Pharmacotherapy, 32, 749–754.

    Article  CAS  PubMed  Google Scholar 

  • Hogg, R. S., Heath, K. V., Yip, B., Craib, K. J., O’Shaughnessy, M. V., Schechter, M. T., et al. (1998). Improved survival among HIV-infected individuals following initiation of antiretroviral therapy. JAMA, 279, 450–454.

    Article  CAS  PubMed  Google Scholar 

  • Liu, H., Golin, C. E., Miller, L. G., Hays, R. D., Beck, C. K., Sanandaji, S., et al. (2001). A comparison study of multiple measures of adherence to HIV protease inhibitors. Annals of Internal Medicine, 134, 968–977.

    CAS  PubMed  Google Scholar 

  • Montori, V. M., Leung, T. W., Thompson, C. A., Chung, J. A., Capes, S. E., & Smith, S. A. (2004). Choice of risk representation to enable diabetes decision-making. Diabetes, 53(Suppl 2), A225.

    Google Scholar 

  • Montori, V. M., & Rothman, R. L. (2005). Weakness in numbers. The challenge of numeracy in health care. Journal of General Internal Medicine, 20, 1071–1072.

    Article  PubMed  Google Scholar 

  • Nieuwkerk, P. T., & Oort, F. J. (2005). Self-reported adherence to antiretroviral therapy for HIV-1 infection and virologic treatment response: A meta-analysis. Journal of Acquired Immune Deficiency Syndromes: JAIDS, 38, 445–448.

    Article  PubMed  Google Scholar 

  • Oyugi, J. H., Byakika-Tusiime, J., Charlebois, E. D., Kityo, C., Mugerwa, R., Mugyenyi, P., et al. (2004). Multiple validated measures of adherence indicate high levels of adherence to generic HIV antiretroviral therapy in a resource-limited setting. Journal of Acquired Immune Deficiency Syndromes: JAIDS, 36, 1100–1102.

    Article  CAS  PubMed  Google Scholar 

  • Palella, F. J., Jr., Delaney, K. M., Moorman, A. C., Loveless, M. O., Fuhrer, J., Satten, G. A. et al. (1998). Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV outpatient study investigators. The New England Journal of Medicine, 338, 853–860.

    Article  PubMed  Google Scholar 

  • Paterson, D. L., Swindells, S., Mohr, J., Brester, M., Vergis, E. N., Squier, C., et al. (2000). Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133, 21–30.

    CAS  PubMed  Google Scholar 

  • Pearson, C. R., Simoni, J. M., Hoff, P., Kurth, A. E., & Martin, D. P. (2007). Assessing antiretroviral adherence via electronic drug monitoring and self-report: An examination of key methodological issues. AIDS Behavior, 11, 161–173.

    Article  Google Scholar 

  • Peters, E., Vastfjall, D., Slovic, P., Mertz, C. K., Mazzocco, K., & Dickert, S. (2006). Numeracy and decision making. Psychological Science, 17, 407–413.

    Article  PubMed  Google Scholar 

  • Preston, C. C., & Colman, A. M. (2000). Optimal number of response categories in rating scales: Reliability, validity, discriminating power, and respondent preferences. Acta Psychologica, 104, 1–15.

    Article  CAS  PubMed  Google Scholar 

  • Rogers, W. H., Wilson, I. B., Bungay, K. M., Cynn, D. J., & Adler, D. A. (2002). Assessing the performance of a new depression screener for primary care (PC-SAD). Journal of Clinical Epidemiology, 55, 164–175.

    Article  PubMed  Google Scholar 

  • Schaeffer, N. C., & Presser, S. (2003). The science of asking questions. Annual Review of Sociology, 29, 65–88.

    Article  Google Scholar 

  • Schwartz, L. M., Woloshin, S., Black, W. C., & Welch, H. G. (1997). The role of numeracy in understanding the benefit of screening mammography. Annals of Internal Medicine, 127, 966–972.

    CAS  PubMed  Google Scholar 

  • Simoni, J. M., Kurth, A. E., Pearson, C. R., Pantalone, D. W., Merrill, J. O., & Frick, P. A. (2006). Self-report measures of antiretroviral therapy adherence: A review with recommendations for HIV research and clinical management. AIDS Behavior, 10, 227–245.

    Article  Google Scholar 

  • Townsend, J. T., Hu, G. G., & Evans, R. J. (1984). Modeling feature perception in brief displays with evidence for positive interdependencies. Perception and Psychophysics, 36, 35–49.

    CAS  PubMed  Google Scholar 

  • Vanhove, G. F., Schapiro, J. M., Winters, M. A., Merigan, T. C., & Blaschke, T. F. (1996). Patient compliance and drug failure in protease inhibitor monotherapy. JAMA, 276, 1955–1956.

    Article  CAS  PubMed  Google Scholar 

  • Wagner, G. J., Kanouse, D. E., Koegel, P., & Sullivan, G. (2004). Correlates of HIV antiretroviral adherence in persons with serious mental illness. AIDS Care, 16, 501–506.

    Article  CAS  PubMed  Google Scholar 

  • Wagner, G. J., & Rabkin, J. G. (1999). Measuring medication adherence: Is assessment of missed doses sufficient? [letter]. AIDS, 13, 2491–2492.

    Article  CAS  PubMed  Google Scholar 

  • Walsh, J. C., Mandalia, S., & Gazzard, B. G. (2002). Responses to a 1 month self-report on adherence to antiretroviral therapy are consistent with electronic data and virological treatment outcome. AIDS, 16, 269–277.

    Article  PubMed  Google Scholar 

  • Ware, J. J., Kosinski, M., & Keller, S. D. (1996). A 12-item short-form health survey: Construction of scales and preliminary tests of reliability and validity. Medical Care, 34, 220–233.

    Article  PubMed  Google Scholar 

  • Wilson, I. B., Tchetgen, E., & Spiegelman, D. (2001). Patterns of adherence with antiretroviral medications: An examination of between-medication differences. Journal of Acquired Immune Deficiency Syndromes, 28, 259–263.

    CAS  PubMed  Google Scholar 

  • Woloshin, S., Schwartz, L. M., & Welch, H. G. (2005). Patients and medical statistics. Interest, confidence, and ability. Journal of General Internal Medicine, 20, 996–1000.

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

This work was supported by NIDA (R01DA015679), NCRR (K24 RR020300), the Lifespan/Tufts/Brown Center for AIDS Research (P30 AI42853), and the Tufts-New England Medical Center General Clinical Research Center (M01-RR00054).

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Correspondence to Ira B. Wilson.

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Lu, M., Safren, S.A., Skolnik, P.R. et al. Optimal Recall Period and Response Task for Self-Reported HIV Medication Adherence. AIDS Behav 12, 86–94 (2008). https://doi.org/10.1007/s10461-007-9261-4

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  • DOI: https://doi.org/10.1007/s10461-007-9261-4

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