Domains of Life Satisfaction Among Patients Living With HIV: A Factor Analytic Study of the Quality of Life Inventory

This study sought to identify multidimensional factors of life satisfaction in individuals with HIV through a factor analysis of the Quality of Life Inventory (QOLI), and to examine the relationship of these factors to health-related quality of life, depression, and medication adherence. Four quality of life domains emerged: Achievement, Self-Expression, Environment, and Interpersonal Relationships. QOLI means were substantially lower than the normative means and were significantly related to the SF-12 mental (but not the physical) component summary. Multidimensional assessments of quality of life in HIV may help specify targets sensitive to psychosocial interventions.

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REFERENCES

  1. Beck, A. T., Ward, C. H., Mendelson, M., Mock, J., and Erbaugh, J. (1961). An inventory for measuring depression. Archives of General Psychiatry, 4, 561–571.

    PubMed  CAS  Google Scholar 

  2. Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., and Wu, A. W. (2000). Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG adherence instruments. Patient Care Committee and Adherence Working Group of the Outcomes Committee of the Adult AIDS Clinical Trials Group (AACTG). AIDS Care, 12, 255–266.

    PubMed  Article  CAS  Google Scholar 

  3. Cook, J. A., Cohen, M. H., Burke, J., Grey, D., Anastos, K., Kirstein, L., Palacio, H., Richardson, J., Wilson, T., and Young, M. (2002). Effects of depressive symptoms and mental health quality of life on use of highly active antiretroviral therapy among HIV-seropositive women. Journal of Acquired Immune Deficiency Syndrome, 30, 401–409.

    Google Scholar 

  4. Elliott, A. J., Uldall, K. K., Bergam, K., Russo, J., Claypoole, K., and Roy-Byrne, P. P. (1998). Randomized, placebo-controlled trial of paroxetine versus imipramine in depressed HIV-positive outpatients. General Hospital Psychiatry, 155, 367–372.

    CAS  Google Scholar 

  5. Eng, W., Coles, M. E., Heimberg, R. G., and Safren, S. A. (2005). Domains of life satisfaction in social anxiety disorder: Relation to symptoms and response to cognitive-behavioral therapy. Journal of Anxiety Disorders, 19, 143–156.

    PubMed  Article  Google Scholar 

  6. Floyd, F. J., and Widaman, K. F. (1995). Factor analysis in the development and refinement of clinical assessment instruments. Psychological Assessment, 7, 286–299.

    Article  Google Scholar 

  7. Frisch, M. B. (1994). Quality of Life Inventory: Manual and treatment guide. Minneapolos, MN: NCS Pearson.

    Google Scholar 

  8. Kalichman, S. C., Ramachandran, B., and Ostrow, D. (1998). Protease inhibitors and the new AIDS combination therapies: Implications for psychological services. Professional Psychology: Research and Practice, 29, 349–356.

    Article  Google Scholar 

  9. Miners, A. H., Sabin, C. A., Mocroft, A., Youle, M., Fisher, M., and Johnson, M. (2001). Health-related quality of life in individuals infected with HIV in the era of HAART. HIV Clinical Trials, 2(6), 484–492.

    PubMed  Article  CAS  Google Scholar 

  10. Safren, S. A., K. H. (2003). Use of an on-line pager system to increase adherence to antiretroviral medications. AIDS Care, 15, 787–793.

    PubMed  Article  CAS  Google Scholar 

  11. Safren, S. A., Hendriksen, E. S., Mayer, K. H., Mimiaga, M. J., Pickard, R., and Otto, M. W. (in press). Cognitive behavioral therapy for HIV medication adherence and depression. Cognitive and Behavioral Practice, 11, 415–423.

  12. Safren, S. A., Otto, M. W., Worth, J., Salomon, E., Johnson, W., Mayer, K., and Boswell, S. (2001). Two strategies to increase adherence to HIV antiretroviral medication: Life-Steps and medication monitoring. Behaviour Research and Therapy, 39, 1151–1162.

    PubMed  Article  CAS  Google Scholar 

  13. Safren, S. A., Radomsky, A. S., Otto, M. W., and Salomon, E. (2002). Predictors of psychological well-being in a diverse sample of HIV-positive patients on highly active antiretroviral therapy. Psychosomatics, 43, 478–485.

    PubMed  Article  Google Scholar 

  14. Ware, J., Kosinski, M., and Keller, S. D. (1996). A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Medical Care, 34, 220–233.

    PubMed  Article  Google Scholar 

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ACKNOWLEDGMENTS

Funding from this project came from several sources including a grant from the Massachusetts Department of Public Health, Industry Support (Reminders On-Line, Inc.), and a grant from the National Institute of Mental Health (MH R21 66660). The second author was the principal investigator on these three sources of support.

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Correspondence to Steven A. Safren Ph.D..

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O`Cleirigh, C., Safren, S.A. Domains of Life Satisfaction Among Patients Living With HIV: A Factor Analytic Study of the Quality of Life Inventory. AIDS Behav 10, 53–58 (2006). https://doi.org/10.1007/s10461-005-9027-9

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KEY WORDS:

  • HIV
  • quality of life
  • life satisfaction
  • health related quality of life
  • factor analysis