Abstract
A simple theoretical approach to normal-phase liquid chromatography with binary mobile phase is presented. In the model used the driving force for the retention is competitive adsorption of solutes and both solvents. A new expression for the separation factor is proposed and discussed. An influence of different parameters on the selectivity is shown. The theoretical concepts are illustrated by the selected experimental data.
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Borówko, M., Ościk-Mendyk, B. Selectivity in normal-phase liquid chromatography with binary mobile phase. Adsorption 16, 397–403 (2010). https://doi.org/10.1007/s10450-010-9231-4
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DOI: https://doi.org/10.1007/s10450-010-9231-4