Advertisement

Adsorption

, Volume 14, Issue 2–3, pp 377–387 | Cite as

Adsorption of small uremic toxin molecules on MFI type zeolites from aqueous solution

  • D. Bergé-Lefranc
  • H. Pizzala
  • J. L. Paillaud
  • O. SchäfEmail author
  • C. Vagner
  • P. Boulet
  • B. Kuchta
  • R. Denoyel
Article

Abstract

Adsorption properties of zeolites were investigated for the removal of p-cresol from aqueous solutions at 37 °C within the context of studying alternative methods to dialysis for removing uremic toxin from blood. MFI-framework type zeolites with different degrees of hydrophobicity and charge compensating cations were prepared: one pure silica MFI and four alumino-silicate MFIs (Si/Al = 30), with H+, Na+, K+ and Mg2+ as charge compensating cations. Adsorption isotherms and microcalorimetric measurements show a high affinity of p-cresol for all MFI type zeolites. The best capacity is obtained for the pure silica MFI, whereas the alumino-silicate samples show a higher affinity in the low concentration range. In the case of pure silica sample, the microscopic adsorption mechanism including the role of confined water is elucidated with the help of NMR, X-ray analysis (including Rietveld refinement) and Monte Carlo simulations. For all samples the high affinity is preserved in physiological serum solution, even in the presence of other toxin molecules such as urea. It is also shown that the compensating cation state of the samples is imposed by the physiological medium.

Keywords

Bioadsorption Uremic toxins p-Cresol Zeolites Monte-Carlo simulations 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Cerius2, Version 4.9. Accelrys, San Diego, CA, USA (2003). Google Scholar
  2. de Vos Burchart, E.: Ph.D. Thesis, Studies on Zeolites: Molecular Mechanics, Framework Stability and Crystal Growth, Table I, Chap. XII (1992) Google Scholar
  3. Denoyel, R.: Colloids Surf. A 205, 61–71 (2002) CrossRefGoogle Scholar
  4. Dou, L., Cerini, C., Brunet, Ph., Guilianelli, C., Moal, V., Grau, G., De Smet, R., Vanholder, R., Sampol, J., Berlan, Y.: Kidney Int. 62, 1999–2009 (2002) CrossRefGoogle Scholar
  5. Eroshenko, V., Regis, R.C., Soulard, M., Patarin, J.: J. Am. Chem. Soc. 123, 8129–8130 (2001) CrossRefGoogle Scholar
  6. Guth, J.L., Delmotte, L., Soulard, M., Brunard, N., Joly, J.F., Espinat, D.: Zeolites 12(8), 929–935 (1992) CrossRefGoogle Scholar
  7. Humphrey, W., Dalke, A., Schulten, K.: J. Mol. Graph. 14, 33–38 (1996) CrossRefGoogle Scholar
  8. Lesaffer, G., De Smet, R., Lameire, N., Dhondt, A., Duym, Ph., Vanholder, R.: Nephrol. Dial. Transplant. 15, 50 (2000) CrossRefGoogle Scholar
  9. Limousin, G., Gaudet, J.-P., Charlet, L., Szenknect, S., Barthès, V., Krimissa, M.: Appl. Geochem. 22, 249–275 (2007) CrossRefGoogle Scholar
  10. Llewellyn, P., Grillet, Y., Patarin, J., Faust, A.C.: Microporous Mesoporous Mater. 1(4), 247–256 (1993) Google Scholar
  11. Lyklema, J.: In: Fundamentals of Interface and Colloid Science, vol. II. Academic, San Diego (1995), Chap. 2 Google Scholar
  12. Mayo, S.L., Olafson, B.D., Goddard III, W.A.: J. Phys. Chem. 94, 8897–8909 (1990) CrossRefGoogle Scholar
  13. Meier, W.M., Olson, D.H., Baerlocher, Ch.: Atlas of Zeolite Structure Types, 4th rev. edn. Elsevier, Amsterdam (1996) Google Scholar
  14. Metropolis, N., Rosenbluth, A.W., Rosenbluth, M.N., Teller, A.N., Teller, E.: J. Chem. Phys. 21, 1087–1092 (1953) CrossRefGoogle Scholar
  15. Robson, H., Lillerud, K.P.: Verified Syntheses of Zeolitic Materials, 2nd rev. edn. Elsevier, Amsterdam (2001) Google Scholar
  16. Van Bekkum, H., Flanigen, E.M., Jacobs, P.A., Jansen, J.C.: Introduction to Zeolite Science and Practice, 2nd rev. edn. Elsevier, Amsterdam (2001) Google Scholar
  17. Vanholder, R., et al.: Kidney Int. 63, 1934–1943 (2003) CrossRefGoogle Scholar
  18. Wernert, V., Schäf, O., Ghobarkar, H., Denoyel, R.: Microporous Mesoporous Mater. 83, 101–113 (2005) CrossRefGoogle Scholar
  19. Wernert, V., Schäf, O., Faure, V., Brunet, P., Dou, L., Berlan, Y., Boulet, P., Kuchta, B., Denoyel, R.: J. Biotechnol. 123, 164–173 (2006) CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • D. Bergé-Lefranc
    • 1
  • H. Pizzala
    • 2
  • J. L. Paillaud
    • 3
  • O. Schäf
    • 1
    Email author
  • C. Vagner
    • 1
  • P. Boulet
    • 1
  • B. Kuchta
    • 1
  • R. Denoyel
    • 1
  1. 1.MADIRELUMR6121 CNRS-Université de ProvenceMarseille Cedex 20France
  2. 2.TRACESUniversité de ProvenceMarseille Cedex 20France
  3. 3.Laboratoire de Matériaux à Porosité ContrôléeUMR CNRS-7016 ENSCMuMulhouse CedexFrance

Personalised recommendations