Skip to main content
Log in

GPT4: The Indispensable Helper for Neurosurgeons in the New Era

  • Letter to the Editor
  • Published:
Annals of Biomedical Engineering Aims and scope Submit manuscript


GPT4 is the newest multimodal language model released by OpenAI. With its powerful capabilities, GPT4 has great potential to revolutionize the healthcare industry. In this study, we proposed various ways GPT4 could display its talents in the field of neurosurgery in future. We believe that GPT4 is prone to become an indispensable assistant for neurosurgeons in the new era.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Data Availability

Not applicable.


  1. Centers for Disease Control and Prevention. National Center for Health Statistics: mortality data on CDC WONDER. 2023.

  2. Cheng, K., Q. Guo, Y. He, Y. Lu, R. Xie, C. Li, and H. Wu. Artificial intelligence in sports medicine: could GPT-4 make human doctors obsolete? Ann. Biomed. Eng. 2023.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Cheng, K., Z. Li, Y. He, Q. Guo, Y. Lu, S. Gu, and H. Wu. Potential use of artificial intelligence in infectious disease: take ChatGPT as an example. Ann. Biomed. Eng. 2023.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Graham, F. Daily briefing: what scientists think of GPT-4, the new AI chatbot. Nature. 2023.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Grünebaum, A., J. Chervenak, S. L. Pollet, A. Katz, and F. A. Chervenak. The exciting potential for ChatGPT in obstetrics and gynecology. Am. J. Obstet. Gynecol. 2023.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Hou, W., and Z. Ji. Reference-free and cost-effective automated cell type annotation with GPT-4 in single-cell RNA-seq analysis. bioRxiv. 2023.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Lecler, A., L. Duron, and P. Soyer. Revolutionizing radiology with GPT-based models: current applications, future possibilities and limitations of ChatGPT. Diagn. Interv. Imaging. 2023.

    Article  PubMed  Google Scholar 

  8. Lee, P., S. Bubeck, and J. Petro. Benefits, limits, and risks of GPT-4 as an AI chatbot for medicine. N. Engl. J. Med. 388:1233–1239, 2023.

    Article  PubMed  Google Scholar 

  9. Louis, D. N., A. Perry, G. Reifenberger, A. von Deimling, D. Figarella-Branger, W. K. Cavenee, H. Ohgaki, O. D. Wiestler, P. Kleihues, and D. W. Ellison. The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol. 131:803–820, 2016.

    Article  PubMed  Google Scholar 

  10. Lyu, Q., J. Tan, M. E. Zapadka, J. Ponnatapura, C. Niu, K. J. Myers, G. Wang, and C. T. Whitlow. Translating radiology reports into plain language using ChatGPT and GPT-4 with prompt learning: promising results, limitations, and potential. 2023.

  11. Nori, H., N. King, S. M. McKinney, D. Carignan, and E. Horvitz. Capabilities of GPT-4 on medical challenge problems. 2023.

  12. Salvagno, M., F. S. Taccone, and A. G. Gerli. Can artificial intelligence help for scientific writing? Crit. Care. 27:75, 2023.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations



All authors contributed to the study conception and design. PL guided the research. GL and XM contributed to writing the original draft. YZ and BS edited the manuscript.

Corresponding author

Correspondence to Pinan Liu.

Ethics declarations

Conflict of interest

The authors declare no conflict of interest.

Ethical Approval

This study does not include any individual-level data and thus does not require any ethical approval.

Additional information

Associate Editor Stefan M. Duma oversaw the review of this article.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Liu, G., Ma, X., Zhang, Y. et al. GPT4: The Indispensable Helper for Neurosurgeons in the New Era. Ann Biomed Eng 51, 2113–2115 (2023).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: