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Alterations in Joint Angular Velocity Following Traumatic Knee Injury in Ovine Models

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Abstract

Little effort has been directed towards the consequence of an injury on joint angular velocity. We hypothesized that the magnitude of knee joint angular velocity would be decreased after injury. Four injury groups were investigated in an ovine model: (1) anterior cruciate ligament (ACL) and medial collateral ligament (MCL) transection (ACL/MCL Tx) (n = 5), (2) lateral meniscectomy (Mx) (n = 5), (3) partial ACL transection (p-ACL Tx) (n = 5), and (4) partial-ACL and MCL transection (p-ACL/MCL Tx) (n = 5). The magnitude of the angular velocities decreased in the subjects of all groups at multiple points of the gait cycle. The maximum angular velocities during stance and the maximum extension angular velocities during swing were decreased in 15/20 and 17/20 subjects, respectively. There were strong correlations between morphological osteoarthritis scores and the reduction in the maximum extension angular velocities during swing 40 weeks post-p-ACL Tx and 20 weeks post-ACL/MCL Tx. There was no correlation between the decrease of the angular velocity and morphological osteoarthritis scores in the Mx group and the p-ACL/MCL Tx group. The reduction in angular velocity may be a helpful addition as a surrogate measure of OA risk after ACL injury, and could have clinical significance after further investigation in humans.

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Acknowledgments

The authors would like to gratefully acknowledge Sarah Flynn, Leslie Jacques, Craig Sutherland, Dean Brown, Vanessa Oliver, Cynddae McGown, Barbara Smith and Yamini Achari for their technical expertise. This work was funded by the Canadian Institutes of Health Research and The Arthritis Society (CBF, NGS, DAH). The authors have not received any financial support that may be perceived as a conflict of interest.

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Author notes

  1. Deceased: Cyril B. Frank.

Authors and Affiliations

  1. McCaig Institute for Bone & Joint Health, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada

    Mehdi Shekarforoush, Kristen I. Barton, C. Ryan Martin, Bryan J. Heard, Johnathan L. Sevick, David A. Hart & Nigel G. Shrive

  2. Schulich School of Engineering, University of Calgary, Calgary, AB, Canada

    Mehdi Shekarforoush, Johnathan L. Sevick & Nigel G. Shrive

  3. Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada

    Mehdi Shekarforoush, Johnathan L. Sevick, David A. Hart & Nigel G. Shrive

  4. Rhode Island Hospital/Brown University, Providence, RI, USA

    Jillian E. Beveridge

  5. Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada

    Michael Scott & Gregory Muench

  6. Section of Orthopaedics, Department of Surgery, University of Calgary, Foothills Hospital, Calgary, AB, Canada

    C. Ryan Martin & David A. Hart

  7. Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada

    David A. Hart

  8. Cumming School of Medicine, Health Sciences Centre, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada

    Cyril B. Frank

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  1. Mehdi Shekarforoush
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Correspondence to Mehdi Shekarforoush.

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Shekarforoush, M., Barton, K.I., Beveridge, J.E. et al. Alterations in Joint Angular Velocity Following Traumatic Knee Injury in Ovine Models. Ann Biomed Eng 47, 790–801 (2019). https://doi.org/10.1007/s10439-019-02203-6

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