Abstract
Many clinical interventional procedures, such as surgery or endoscopy, are today still guided by human vision and perception. Human vision however is not sensitive or accurate in detecting a large range of disease biomarkers, for example cellular or molecular processes characteristic of disease. For this reason advanced optical and opto-acoustic (photo-acoustic) methods are considered for enabling a more versatile, sensitive and accurate detection of disease biomarkers and complement human vision in clinical decision making during interventions. Herein, we outline developments in emerging fluorescence and opto-acoustic sensing and imaging techniques that can lead to practical implementations toward improving interventional vision.
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Sarantopoulos, A., Beziere, N. & Ntziachristos, V. Optical and Opto-Acoustic Interventional Imaging. Ann Biomed Eng 40, 346–366 (2012). https://doi.org/10.1007/s10439-011-0501-4
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DOI: https://doi.org/10.1007/s10439-011-0501-4