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A Physiologically Relevant, Simple Outflow Boundary Model for Truncated Vasculature

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Abstract

A realistic outflow boundary condition model for pulsatile flow in a compliant vessel is studied by taking into account physiological effects: compliance, resistance, and wave reflection of the downstream vasculature. The new model extends the computational domain with an elastic tube terminated in a rigid contraction. The contraction ratio, the length, and elasticity of the terminal tube can be adjusted to represent effects of the truncated vasculature. Using the wave intensity analysis method, we apply the model to the test cases of a straight vessel and the aorta and find good agreement with the physiological characteristics of blood flow and pressure. The model is suitable for cardiac transient (non-periodic) events and easily employed using so-called black box software.

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Authors and Affiliations

  1. Division of Engineering and Applied Sciences, California Institute of Technology, 1200 East California Blvd., Pasadena, CA, 91125, USA

    Niema M. Pahlevan, Faisal Amlani & Morteza Gharib

  2. Institute of Fluid Dynamics, ETH Zurich, Zurich, Switzerland

    M. Hossein Gorji

  3. Department of Mechanical Engineering, University of Houston, Houston, TX, USA

    Fazle Hussain

Authors
  1. Niema M. Pahlevan
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  2. Faisal Amlani
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  3. M. Hossein Gorji
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  4. Fazle Hussain
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  5. Morteza Gharib
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Correspondence to Morteza Gharib.

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Associate Editor Peter E. McHugh oversaw the review of this article.

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Pahlevan, N.M., Amlani, F., Hossein Gorji, M. et al. A Physiologically Relevant, Simple Outflow Boundary Model for Truncated Vasculature. Ann Biomed Eng 39, 1470–1481 (2011). https://doi.org/10.1007/s10439-011-0246-0

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  • DOI: https://doi.org/10.1007/s10439-011-0246-0

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