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Vascular Dynamics of a Shape Memory Polymer Foam Aneurysm Treatment Technique

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Abstract

The vascular dynamics of a shape memory polymer foam aneurysm treatment technique are assessed through the simulated treatment of a generic basilar aneurysm using coupled fluid dynamics and heat transfer calculations. The shape memory polymer foam, which expands to fill the aneurysm when heated, is modeled at three discrete stages of the treatment procedure. To estimate an upper bound for the maximum amount of thermal damage due to foam heating, a steady velocity is specified through the basilar artery, corresponding to a minimum physiological flow velocity over a cardiac cycle. During expansion, the foam alters the flow patterns within the aneurysm by shielding the aneurysm dome from a confined jet that issues from the basilar artery. The time scales for thermal damage to the artery walls and surrounding blood flow are computed from the temperature field. The flow through the post-treatment bifurcation is comprised of two counter-rotating vortex tubes that are located beneath the aneurysm neck and extend downstream into the outlet arteries. Beneath the aneurysm neck, a marked increase in the wall shear stress is observed due to the close proximity of the counter-rotating vortex tubes to the artery wall.

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Abbreviations

CFD:

computational fluid dynamics

GDC:

Guglielmi detachable coil

SMP:

shape memory polymer

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Acknowledgments

The authors would like to thank K. Salari for his guidance on the CFD simulations and P. Castellucci, J. Paschkewitz, and W. Small for their helpful feedback in the manuscript preparation. This work was performed under the auspices of the U.S. Department of Energy by the University of California, Lawrence Livermore National Laboratory under Contract No. W-7405-Eng-48. Major support provided by the National Institutes of Health/National Institute of Biomedical Imaging and Bioengineering, Grant R01EB000462. Additional support was provided by a LLNL Directed Research and Development Grant (04-ERD-093). UCRL-JRNL-219283.

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  1. Engineering, Lawrence Livermore National Laboratory, P.O. Box 808, L-644, Livermore, CA, 94551, USA

    Jason Ortega

  2. Physics and Advanced Technologies, Lawrence Livermore National Laboratory, Livermore, CA, 94551, USA

    Duncan Maitland & Tom Wilson

  3. U.C. Berkeley, Berkeley, CA, 94720, USA

    William Tsai & Ömer Savaş

  4. U.C. San Francisco, San Francisco, CA, 94121, USA

    David Saloner

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Ortega, J., Maitland, D., Wilson, T. et al. Vascular Dynamics of a Shape Memory Polymer Foam Aneurysm Treatment Technique. Ann Biomed Eng 35, 1870–1884 (2007). https://doi.org/10.1007/s10439-007-9358-y

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