Abstract
The heterozygosity of CANP3, ACTN3, and GHR genes in specialized collections was studied using state-of-the-art DNA technologies for DNA analysis. A new dinucleotide deletion (AC) at the beginning of exon 21 was identified in five individuals with a heterozygous CANP3 gene. Analysis of polymorphism (1747 C → T) of the ACTN3 gene demonstrated a positive association of allele C with high muscular performance. Real-time PCR assay of SNP1630 (A → C) in the GHR gene suggested a putative negative association of allele C of this SNP with high muscular performance.
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Translated from Prikladnaya Biokhimiya i Mikrobiologiya, Vol. 41, No. 3, 2005, pp. 303–307.
Original Russian Text Copyright © 2005 by Krakhmaleva, Shishkin, Shakhovskaya, Stolyarova, Plugov, Knyazev, Khomenkov, Shevelev, Chernov.
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Krakhmaleva, I.N., Shishkin, S.S., Shakhovskaya, N.I. et al. SNP-detecting DNA technologies: Solving problems of applied biochemistry. Appl Biochem Microbiol 41, 264–268 (2005). https://doi.org/10.1007/s10438-005-0045-1
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DOI: https://doi.org/10.1007/s10438-005-0045-1