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Die extrapulmonalen Auswirkungen der Lungenüberblähung bei COPD

Extrapulmonary consequences of lung hyperinflation in COPD

  • Leitthema
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Zusammenfassung

Die extrapulmonalen Auswirkungen der Lungenüberblähung betreffen Herzfunktion und Muskulatur von Patienten mit COPD. So ist ein Zusammenhang zwischen der Überblähung der Lunge bei COPD und der verminderten Füllung des Herzens in verschiedenen Untersuchungen gezeigt worden. Die verminderte kardiale Füllung führt wiederum zu einem verminderten Schlagvolumen und verstärkt möglicherweise die Belastungsintoleranz bei COPD. Interventionelle Maßnahmen zur Reduktion der Lungenüberblähung bewirken eine verbesserte kardiale Funktion. Durch die belastungsintoleranzinduzierte Dekonditionierung ist indirekt auch die Skelettmuskulatur von der Lungenüberblähung betroffen.

Abstract

Cardiac dysfunction and skeletal muscle dysfunction are extrapulmonary consequences of lung hyperinflation in chronic obstructive pulmonary disease (COPD). Several studies demonstrated that lung hyperinflation is related to an underfilling of the heart, which in turn leads to a reduced cardiac output and is associated with a further worsening of exercise intolerance in COPD. Interventional studies showed that cardiac function can be improved by interventional measures for reduction of lung hyperinflation. Skeletal muscle deconditioning due to exercise intolerance is an indirect consequence of lung hyperinflation in COPD.

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Authors and Affiliations

  1. Pneumologisches Forschungsinstitut an der LungenClinic Grosshansdorf, Wöhrendamm 80, 22927, Großhansdorf, Deutschland

    H. Watz

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  1. H. Watz
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Correspondence to H. Watz.

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H. Watz gibt an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von dem Autor durchgeführten Studien an Menschen oder Tieren.

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H. Worth, Fürth

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Watz, H. Die extrapulmonalen Auswirkungen der Lungenüberblähung bei COPD. Pneumologe 14, 20–23 (2017). https://doi.org/10.1007/s10405-016-0086-6

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  • DOI: https://doi.org/10.1007/s10405-016-0086-6

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