Skip to main content
SpringerLink
Log in

Die Rolle der Schlafmedizin bei Herz-Kreislauf-Erkrankungen

Schlaf und kardiovaskuläre Erkrankungen – Teil 1

The role of sleep medicine in cardiovascular diseases

Sleep and cardiovascular diseases – part 1

  • Leitthema
  • Published:
Der Pneumologe Aims and scope

Zusammenfassung

Die Bedeutung eines gestörten Schlafs für die Entstehung kardiovaskulärer Erkrankungen ist bislang nur unzureichend untersucht. Auch bei manifesten kardiovaskulären Erkrankungen gibt es nur wenige Untersuchungen zu schlafmedizinischen Komorbiditäten jenseits von schlafbezogenen Atmungsstörungen. Dabei ist aber gut vorstellbar, dass der Schlaf per se mit seinen Variablen Schlafqualität und -quantität, neuronaler, endokriner, metabolischer und muskulärer Aktivität sowie Sauerstoffversorgung und -bedarf bei der Entstehung, der Behandlung und auch der Prognose kardiovaskulärer Erkrankungen eine große Rolle spielen könnte. Aufgrund des hohen Standards der deutschen Schlafmedizin ergibt sich gerade hier die Möglichkeit, entsprechende prospektive und ausreichend große Studien in Zusammenarbeit mit anderen Fachdisziplinen und insbesondere mit Kardiologen und Epidemiologen auf den Weg zu bringen.

Abstract

Sleep disorders are greatly underdiagnosed and underappreciated comorbidities in patients with cardiovascular diseases. In addition, sleep per se with metrics of sleep duration, sleep quality, neuronal, endocrinal, metabolic and muscular activities as well as the resulting oxygen supply and demand, needs to be systematically investigated to identify a potentially crucial role in the development, progression and prognosis of cardiovascular diseases. The high standards in German sleep medicine allow the initiation of appropriate large and prospective trials in cooperation between sleep doctors and physicians of other disciplines, including cardiologists and epidemiologists.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Silvani A, Dampney RA (2013) Central control of cardiovascular function during sleep. Am J Physiol Heart Circ Physiol 305:1683–1692

    Article  Google Scholar 

  2. Gottlieb DJ, Redline S, Nieto FJ et al (2006) Association of usual sleep duration with hypertension: the sleep heart health study. Sleep 29:1009–1014

    PubMed  Google Scholar 

  3. Hoevenaar-Blom MP, Spijkerman AM, Kromhout D et al (2013) Sufficient sleep duration contributes to lower cardiovascular disease risk in addition to four traditional lifestyle factors: the morgen study. Eur J Prev Cardiol (Epub ahead of print)

  4. Gangwisch JE (2014) A review of evidence for the link between sleep duration and hypertension. Am J Hypertens (Epub ahead of print)

  5. Arzt M, Young T, Finn L et al (2006) Sleepiness and sleep in patients with both systolic heart failure and obstructive sleep apnea. Arch Intern Med 166:1716–1722

    Article  PubMed  Google Scholar 

  6. Redeker NS, Adams L, Berkowitz R et al (2012) Nocturia, sleep and daytime function in stable heart failure. J Card Fail 18:569–575

    Article  PubMed Central  PubMed  Google Scholar 

  7. Redline S, Kirchner HL, Quan SF et al (2004) The effects of age, sex, ethnicity, and sleep-disordered breathing on sleep architecture. Arch Intern Med 164:406–418

    Article  PubMed  Google Scholar 

  8. Ayas NT, White DP, Manson JE et al (2003) A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med 163:205–209

    Article  PubMed  Google Scholar 

  9. Chandola T, Ferrie JE, Perski A et al (2010) The effect of short sleep duration on coronary heart disease risk is greatest among those with sleep disturbance: a prospective study from the whitehall ii cohort. Sleep 33:739–744

    PubMed Central  PubMed  Google Scholar 

  10. Cappuccio FP, D’Elia L, Strazzullo P et al (2010) Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies. Sleep 33:585–592

    PubMed Central  PubMed  Google Scholar 

  11. Patel SR, Ayas NT, Malhotra MR et al (2004) A prospective study of sleep duration and mortality risk in women. Sleep 27:440–444

    PubMed  Google Scholar 

  12. Meng L, Zheng Y, Hui R (2013) The relationship of sleep duration and insomnia to risk of hypertension incidence: a meta-analysis of prospective cohort studies. Hypertens Res 36:985–995

    Article  PubMed Central  PubMed  Google Scholar 

  13. Knutson KL, Spiegel K, Penev P et al (2007) The metabolic consequences of sleep deprivation. Sleep Med Rev 11:163–178

    Article  PubMed Central  PubMed  Google Scholar 

  14. Meerlo P, Sgoifo A, Suchecki D (2008) Restricted and disrupted sleep: effects on autonomic function, neuroendocrine stress systems and stress responsitivity. Sleep Med Rev 12:197–210

    Article  PubMed  Google Scholar 

  15. Reinhard W, Plappert N, Zeman F et al (2013) Prognostic impact of sleep duration and sleep efficiency on mortality in patients with chronic heart failure. Sleep Med 14:502–509

    Article  PubMed  Google Scholar 

  16. Türoff A, Fox H, Bitter T et al (2013) Herzinsuffizienz und Schlafqualität bei zentraler und obstruktiver schlafbezogener Atmungsstörung. Herzschrittmacherther Elektrophysiol 24(Suppl 1):42–43

    Google Scholar 

  17. Magee CA, Holliday EG, Attia J et al (2013) Investigation of the relationship between sleep duration, all-cause mortality, and preexisting disease. Sleep Med 14:591–596

    Article  PubMed  Google Scholar 

  18. Kurina LM, McClintock MK, Chen JH et al (2013) Sleep duration and all-cause mortality: a critical review of measurement and associations. Ann Epidemiol 23:361–370

    Article  PubMed Central  PubMed  Google Scholar 

Download references

Einhaltung ethischer Richtlinien

Interessenkonflikt. O. Oldenburg, A. Türoff, J. Spiesshöfer, T. Bitter, H. Fox und D. Horstkotte geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

Author information

Authors and Affiliations

  1. Kardiologische Klinik, Herz- und Diabeteszentrum NRW, Universitätsklinikum, Ruhr-Universität Bochum, Georgstr. 11, 32545, Bad Oeynhausen, Deutschland

    O. Oldenburg, A. Türoff, J. Spiesshöfer, T. Bitter, H. Fox & D. Horstkotte

  2. Klinik für Pneumologie, Medizinische Hochschule, Hannover, Deutschland

    T. Bitter

  3. Zentrale Notaufnahme, Asklepios Klinik Wandsbek, Hamburg, Deutschland

    A. Türoff

Authors
  1. O. Oldenburg
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Türoff
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Spiesshöfer
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. T. Bitter
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. H. Fox
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. D. Horstkotte
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to O. Oldenburg.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Oldenburg, O., Türoff, A., Spiesshöfer, J. et al. Die Rolle der Schlafmedizin bei Herz-Kreislauf-Erkrankungen. Pneumologe 11, 413–415 (2014). https://doi.org/10.1007/s10405-014-0814-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10405-014-0814-8

Schlüsselwörter

Keywords

Search

Navigation