Literatur
Bateman ED (2013) Tiotropium Respimat increases the risk of mortality: con. Eur Respir J 42:590–593
Celli B, Decramer M, Kesten S et al (2009) Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 180:948–955
Ichinose M, Fujimoto T, Fukuchi Y (2010) Tiotropium 5 µg via Respimat and 18 µg via HandiHaler; efficacy and safety in Japanese COPD patients. Respir Med 104:228–236
Loke YK, Singh S, Furberg CD (2014) Tiotropium and the risk of death in COPD. N Engl J Med 370:480–481
Noord JA van, Cornelissen PJ, Aumann JL et al (2009) The efficacy of tiotropium administered via Respimat Soft Mist Inhaler or HandiHaler in COPD patients. Respir Med 103:22–29
Singh S, Loke YK, Enright PL, Furberg CD (2011) Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled trials. BMJ 342:3215
Tashkin DP, Celli B, Senn S et al (2008) A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 359:1543–1554
Verhamme KM, Afonso A, Romio S et al (2013) Use of tiotropium Respimat Soft Mist Inhaler versus HandiHaler and mortality in patients with COPD. Eur Respir J 42:606–615
Einhaltung ethischer Richtlinien
Interessenkonflikt. N. Waldburg gibt an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Waldburg, N. Ergebnis der TIOSPIR-Studie und deren Auswirkungen auf die Wertigkeit von Metaanalysen. Pneumologe 11, 437–440 (2014). https://doi.org/10.1007/s10405-013-0755-7
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10405-013-0755-7