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Idiopathische Lungenfibrose

Diagnostik und Differenzialdiagnose

Idiopathic pulmonary fibrosis

Diagnostics and differential diagnosis

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Zusammenfassung

Die idiopathische pulmonale Lungenfibrose (IPF) wird nach Ausschluss von Differenzialdiagnosen durch das Vorliegen eines UIP-Musters im hochauflösenden Computertomogramm (HRCT) bei Patienten ohne chirurgische Lungenbiopsie bzw. durch bestimmte Musterkombinationen im HRCT und im Biopsiebefund diagnostiziert. Darüber hinaus umfasst die Initialdiagnostik die Erkennung bestehender Komorbiditäten und initiale funktionelle Parameter. Von Bedeutung ist die interdisziplinäre Diskussion der Befunde.

Abstract

The diagnosis of idiopathic pulmonary fibrosis (IPF) is based on a usual interstitial pneumonia (UIP) pattern on high-resolution computed tomography (HRCT) in patients not subjected to surgical lung biopsy or specific combinations of HRCT with histopathological patterns after exclusion of known causes of interstitial lung disease. The diagnostic work-up should also include initial lung function and the diagnosis of comorbidities. The interdisciplinary discussion of clinical, radiological and histological data is essential.

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Interessenkonflikt

C.P. Heussel und M. Kreuter erhielten Forschungsförderung sowie Honorare für Referate von InterMune, C.P. Heussel zudem von Siemens, Essex, Astra-Zeneca, Bracco, MEDA Pharma, Chiesi, Covidien, Pierre Fabre und Grifols. C.P. Heussel erhielt außerdem Honorare von Schering Plough, Pfizer, Basilea, Boehringer Ingelheim, Novartis, Roche, Astellas, Gilead, MSD und Lilly. A. Warth und H. Wenz gaben keine Interessenkonflikte in Bezug auf die Inhalte dieses Artikels an.

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Authors and Affiliations

  1. Pneumologie und Beatmungsmedizin, Thoraxklinik, Universitätsklinikum Heidelberg, Amalienstr. 5, 69126, Heidelberg, Deutschland

    M. Kreuter & H. Wenz

  2. Pathologisches Institut, Universitätsklinikum Heidelberg, Heidelberg, Deutschland

    A. Warth

  3. Diagnostische und interventionelle Radiologie mit Nuklearmedizin, Thoraxklinik, Universitätsklinikum Heidelberg, Heidelberg, Deutschland

    C. P. Heussel

  4. Deutsches Lungenforschungszentrum (DLZ), Heidelberg, Deutschland

    M. Kreuter & C. P. Heussel

Authors
  1. M. Kreuter
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  2. A. Warth
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  3. H. Wenz
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  4. C. P. Heussel
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Correspondence to M. Kreuter.

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Kreuter, M., Warth, A., Wenz, H. et al. Idiopathische Lungenfibrose. Pneumologe 10, 89–97 (2013). https://doi.org/10.1007/s10405-012-0606-y

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  • DOI: https://doi.org/10.1007/s10405-012-0606-y

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