In this paper, we describe a large-scale microfluidic valve platform for thermally actuated phase change (PC) microvalves. PC microvalves can be actuated by heat sources such as ohmic resistors, which can be highly integrated resulting in dense arrays of individually addressable microfluidic valves. We present a custom-made electronic platform with custom-written control software that allows controlling a total of 588 individually addressable resistors each of which can be used as the actuator for a separate PC valve. The platform is demonstrated with direct PC microvalve (the simplest example of a PC valve) where working fluid and phase change material are the same media. We present experimental results for single valve setups as well as for a 24 microvalve setup showing the scalability of the system. Furthermore, we demonstrate that precise and individual ‘per-resistor’ temperature profiles are required for valve actuation in order to decrease thermal latency and ensure that the time required for switching the valve state is independent from the “thermal history” (i.e. the duration of the previous valve state) of the valve. To the best of our knowledge, there is no such platform described in the literature, which offers an equal potential for individual valve operation (potentially up to 588 individual valves) as presented in this work.
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This work was funded in part by the ‚Concept for the Future’ of Karlsruhe Institute of Technology (KIT) within the framework of the German Excellence Initiative, a Max-Buchner Research fellowship (DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie e. V., Grant #2676) as well as a travelling grant provided by the Karlsruhe House of Young Scientists (KHYS).
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Neumann, C., Voigt, A., Pires, L. et al. Design and characterization of a platform for thermal actuation of up to 588 microfluidic valves. Microfluid Nanofluid 14, 177–186 (2013). https://doi.org/10.1007/s10404-012-1036-1
- Microfluidic valves
- Thermal actuation
- Phase change