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Novel ferrofluids coated with a renewable material obtained from cashew nut shell liquid

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In this work, we present the synthesis and characterization of a new surfactant molecule obtained from a byproduct of the cashew nut processing (diphosphorylated cardol, DPC). It is herein used to overcoat magnetic nanoparticles showing spinel structures in order to create new ferrofluids. The nanoparticle structure and magnetic properties have been deeply investigated. DPC-functionalized Fe3O4 and NiFe2O4 samples exhibit higher magnetic saturation than DPC–CoFe2O4. These new ferrofluids reveal appealing as possible nanoparticle stabilizing molecules, magnetic resonance imaging agents, storage systems or in any material science field that requires the employment of biocompatible magnetic stable fluids.

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  1. Albuquerque AS, Ardisson JD, Macedo WAA, López JL, Paniago R, Persiano AIC (2001) Structure and magnetic properties of nanostructure Ni-ferrite. J Magn Magn Mater 226–230:1379–1381

  2. Ayyappan S, Philip J, Raj B (2009) A facile method to control the size and magnetic properties of CoFe2O4 nanoparticles. Mater Chem Phy 115:712–717

  3. Barreto ACH, Santiago VR, Mazzetto SE, Denardin JC, Lavín R, Mele G, Ribeiro MENP, Vieira IGP, Gonçalves T, Ricardo NMPS, Fechine PBA (2011) Magnetic nanoparticles for a new drug delivery system to control quercetin for cancer chemotherapy. J Nanopart Res. doi:10.1007/s11051-011-0559-9

  4. Boyer C, Whittaker MR, Bulmus V, Liu J, Davis TP (2010) The design and utility of polymer-stabilized iron-oxide nanoparticles for nanomedicine applications. NPG Asia Mater 2:23–30

  5. Chinnasamy CN, Narayanasamy A, Ponpandian N, Chattopadhyay K, Shinoda K, Jeyadevan B, Tohji K, Nakatsuka K, Furubayashi T, Nakatani I (2001) Mixed spinel structure in nanocrystalline NiFe2O4. Phys Rev B 63:184108–184114

  6. Chitu L, Jergel M, Majkova E, Luby S, Capek I, Satka A (2007) Structure and magnetic properties of CoFe2O4 and Fe3O4 nanoparticles. Mater Sci Eng C 27:1415–1417

  7. Cote LJ, Teja AS, Wilkinson AP, Zhang ZJ (2003) Continuous hydrothermal synthesis of CoFe2O4 nanoparticles. Fluid Phase Equilib 210:307–317

  8. Durmus Z, Erdemi H, Aslan A, Toprak MS, Sozeri H, Baykal A (2011) Synthesis and characterization of poly(vinyl phosphonic acid) (PVPA)–Fe3O4 nanocomposite. Polyhedron 30:419–426

  9. Façanha MAR, Mazzetto SE, Carioca JOB, de Barros GG (2007) Evaluation of antioxidant properties of a phosphorated cardanol compound on mineral oils (NH10 and NH20). Fuel 86:2416–2421

  10. Gyergyek S, Makovec D, Drofenik M (2011) Colloidal stability of oleic- and ricinoleic-acid-coated magnetic nanoparticles in organic solvents. J Colloid Interface Sci 354:498–505

  11. Hrdina A, Lai E, Li C, Sadi B, Kramer G (2010) A comparative study of magnetic transferability of superparamagnetic nanoparticles. J Magn Magn Mater 322:2622–2627

  12. Hu FX, Neoh KG, Kang ET (2006) Synthesis and in vitro anti-cancer evaluation of tamoxifen-loaded magnetite/PLLA composite nanoparticles. Biomaterials 27:5725–5733

  13. Kim YI, Kim D, Lee CS (2003) Synthesis and characterization of CoFe2O4 magnetic nanoparticles prepared by temperature-controlled coprecipitation method. Phys B 337:42–51

  14. Kim EH, Lee HS, Kwak BK, Kim BK (2005) Synthesis of ferrofluid with magnetic nanoparticles by sonochemical method for MRI contrast agent. J Magn Magn Mater 289:328–330

  15. Kumari A, Yadav SK, Pakade YB, Singh B, Yadav SC (2010) Development of biodegradable nanoparticles for delivery of quercetin. Colloids Surf B 80:184–192

  16. Laokul P, Amornkitbamrung V, Seraphin S, Maensiri S (2011) Characterization and magnetic properties of nanocrystalline CuFe2O4, Ni Fe2O4, ZnFe2O4 powders prepared by the Aloe vera extract solution. Curr Appl Phys 11:101–108

  17. Li G, Jiang Y, Huang K, Ding P, Chen J (2008) Preparation and properties of magnetic Fe3O4–chitosan nanoparticles. J Alloys Comp 466:451–456

  18. Maia FJN, Ribeiro VG, Clemente CSC, Lomonaco, D, Vasconcelos PHM, Mazzetto SE (2011) Thermo-oxidative evaluation of new cardol derivatives as antioxidants for mineral oils. J Therm Anal Calorim. doi:10.1007/s10973-011-1870-5

  19. Lomonaco D, Cangane FY, Mazzetto SE (2011) Thiophosphate esters of cashew nutshell liquid derivatives as new antioxidants for poly(methyl methacrylate). J Therm Anal Calorim 104:1177–1183

  20. Lopes AAS, Carneiro EA, Rios MAS, Hiluy Filho JJ, Carioca JOB, Barros GG, Mazzetto SE (2008) Study of antioxidant property of a thiosphorated compound derived from cashew nut shell liquid in hydrogenated naphthenics oils. Braz J Chem Eng 25:119–127

  21. Maia AOG, Meneses CT, Menezes AS, Flores WH, Melo DMA, Sasaki JM (2006) Synthesis and X-ray structural characterization of NiO nanoparticles obtained through gelatin. J Non-Cryst Sol 352:3729–3733

  22. Mazzetto SE, Lomonaco D, Mele G (2009) Cashew nut oil: opportunities and challenges in the context of sustainable industrial development. Quim Nova 32:732–741

  23. Meerod S, Tumcharem G, Wichai U, Rutnakorpituk M (2008) Magnetite nanoparticles stabilized with polymeric bilayer of poly(ethylene glycol) methyl ether-poly(-caprolactone) copolymers. Polymer 49:3950–3956

  24. Mele G, Vasapollo G (2008) Fine chemicals and new hybrids materials from cardanol. Mini Rev Org Chem 5:243–253

  25. Paramashivappa R, Phani Kumar P, Vithayathil PJ, Srinivasa Rao A (2001) Novel method for isolation of major phenolic constituents from cashew (Anacardium occidentale L.) nut shell liquid. J Agric Food Chem 49:2548–2551

  26. Passamani EC, Segatto BR, Larica C, Cohen R, Greneche JM (2010) Magnetic hysteresis loop shift in NiFe2O4 nanocrystalline powder with large grain boundary fraction. J Magn Magn Mater 322:3917–3925

  27. Patel RN, Bandyopadhyay S, Ganesh A (2006) Extraction of cashew (Anacardium occidentale) nut shell liquid using supercritical carbon dioxide. Biores Technol 97:847–853

  28. Philip JY, Buchweishaija J, Mkayula LL, Ye L (2007) Preparation of molecularly imprinted polymers using anacardic acid monomers derived from cashew nut shell liquid. J Agric Food Chem 55:8870–8876

  29. Rao BP, Rao GSN, Kumar AM, Rao KH, Murthy YLN, Hong SM, Kim CO, Kim C (2007) Soft chemical synthesis and characterization of Ni0.65Zn0.35Fe2O4 nanoparticles. J Appl Phys 101:123902-1–123902-4

  30. Rietveld HM (1967) Line profiles of neutron powder-diffraction peaks for structure refinement. Acta Cryst 22:151–152

  31. Rios MAS, Nascimento TL, Santiago SN, Mazzetto SE (2009) Cashew nut shell liquid: a versatile raw material utilized for syntheses of phosphorus compounds. Energy Fuels 23:5432–5437

  32. Sahoo Y, Pizem H, Fried T, Golodnitsky D, Burstein L, Sukenik CN, Markovich G (2001) Alkyl phosphonate/phosphate coating on magnetite nanoparticles: a comparison with fatty acids. Langmuir 17:7907–7911

  33. Setianto WB, Yoshikawa S, Smith RL Jr, Inomatab H, Florussed LJ, Peterse CJ (2009) Pressure profile separation of phenolic liquid compounds from cashew (Anacardium occidentale) shell with supercritical carbon dioxide and aspects of its phase equilibria. J Supercrit Fluid 48:203–210

  34. Shen L, Laibinis PE, Hatton TA (1999) Bilayer surfactant stabilized magnetic fluids: synthesis and interactions at interfaces. Langmuir 15:447–453

  35. Shi Y, Ding J, Liu X, Wang J (1999) NiFe2O4 ultrafine particles prepared by co-precipitation/mechanical alloying. J Magn Magn Mater 205:249–254

  36. Slavov L, Abrashev MV, Merodiiska T, Gelev Ch, Vandenberghe RE, Deneva IM, Nedkov I (2010) Raman spectroscopy investigation of magnetic nanoparticles in ferrofluids. J Magn Magn Mater 322:1904–1911

  37. Trevisan MT, Pfundstein B, Haubner R, Wurtele G, Spiegelhalder B, Bartsch H, Owen RW (2006) Characterization of alkyl phenols in cashew (Anacardium occidentale) products and assay of their antioxidant capacity. Food Chem Toxicol 44:188–197

  38. Valenzuela R, Fuentes MC, Parra C, Baeza J, Duran N, Sharma SK, Knobel M, Freer J (2009) Influence of stirring velocity on the synthesis of magnetite nanoparticles (Fe3O4) by the co-precipitation method. J Alloy Comp 488:227–231

  39. Waje SB, Hashim M, Yusoff WDW, Abbas Z (2010) X-ray diffraction studies on crystallite size evolution of CoFe2O4 nanoparticles prepared using mechanical alloying and sintering. App Surf Sci 256:3122–3127

  40. Wang Z, Shen B, Aihua Z, He N (2003) Synthesis of Pd/Fe3O4 nanoparticle-based catalyst for the cross-coupling of acrylic acid with iodobenzene. Chem Eng J 113:27–34

  41. Xu Z, Shen C, Hou Y (2009) Oleylamine as both reducing agent and stabilizer in a facile synthesis of magnetite nanoparticles. Chem Matter 21:1778–1780

  42. Young RA, Sakthivel A, Moss TS, Santos COP (1995) DBWS-9411 - an upgrade of the DBWS programs for Rietveld refinement with PC and mainframe computers. J Appl Cryst 28:366–367

  43. Zhao DL, Zeng XW, Xia QS, Tang JT (2009) Preparation and coercivity and saturation magnetization dependence of inductive heating property of Fe3O4 nanoparticles in an alternating current magnetic field for localized hyperthermia. J Alloy Comp 469:215–218

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This work was supported by CAPES, Funcap and CNPq (Brazilian agencies). The support from Fondecyt 1110252, Millennium Science Nucleus, Basic and Applied Magnetism Grant No. P10-061-F and CONICYT BASAL CEDENNA FB0807, is gratefully acknowledged. The authors thank CENAUREM (Centro Nordestino de Aplicação e Uso da Ressonância Magnética Nuclear) for the NMR analyses.

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Correspondence to P. B. A. Fechine.

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Barreto, A.C.H., Maia, F.J.N., Santiago, V.R. et al. Novel ferrofluids coated with a renewable material obtained from cashew nut shell liquid. Microfluid Nanofluid 12, 677–686 (2012).

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  • Ferrofluids
  • Magnetic nanoparticles
  • Cardol
  • Phosphorylated compounds