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Syndromic Surveillance of Respiratory Disease in Free-Living Chimpanzees

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Abstract

Disease surveillance in wildlife is rapidly expanding in scope and methodology, emphasizing the need for formal evaluations of system performance. We examined a syndromic surveillance system for respiratory disease detection in Gombe National Park, Tanzania, from 2004 to 2012, with respect to data quality, disease trends, and respiratory disease detection. Data quality was assessed by examining community coverage, completeness, and consistency. The data were examined for baseline trends; signs of respiratory disease occurred at a mean frequency of less than 1 case per week, with most weeks containing zero observations of abnormalities. Seasonal and secular (i.e., over a period of years) trends in respiratory disease frequency were not identified. These baselines were used to develop algorithms for outbreak detection using both weekly counts and weekly prevalence thresholds and then compared retrospectively on the detection of 13 respiratory disease clusters from 2005 to 2012. Prospective application of outbreak detection algorithms to real-time syndromic data would be useful in triggering a rapid outbreak response, such as targeted diagnostic sampling, enhanced surveillance, or mitigation.

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Acknowledgements

We thank the staff of the Jane Goodall Institute’s Gombe Stream Research Centre for collecting daily health observations, as well as to the Gombe Ecosystem Health Project staff who manage and organize the data as it originates from the field. Thanks also to Andres Perez for insight and direction on time series analysis and Richard Maclehose for the constructive feedback on other aspects of the biostatistical analyses. Alex Krupnick, Emma Finestone, Emma Lantz, Emily Seidl, Anna Sjodin, and Edward Wilkerson provided key data management support. We also thank the Tanzania Commission for Science and Technology (COSTECH), Tanzania Wildlife Research Institute (TAWIRI), and Tanzania National Parks Association (TANAPA) for their continued support and approval of this research. Funding support comes from the Zoetis/Morris Animal Foundation Veterinary Research Fellowship [D10ZO-902] and the University of Minnesota Doctoral Dissertation Fellowship, the National Institute of Health (R01 AI058715, R01 AI 120810 and R00 HD057992), National Science Foundation (LTREB-1052693), Arcus Foundation, USFWS Great Ape Conservation Fund. Monetary support and invaluable time and effort were provided by staff and volunteers at Lincoln Park Zoo’s Davee Center for Epidemiology and Endocrinology and Lester E. Fisher for the Study and Conservation of Apes.

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Authors and Affiliations

  1. Veterinary Population Medicine, University of Minnesota, 495 Animal Science/Veterinary Medicine, 1988 Fitch Ave, St. Paul, MN, 55108, USA

    Tiffany M. Wolf & Dominic A. Travis

  2. Veterinary Biomedical Sciences, University of Minnesota, 1971 Commonwealth Ave, St. Paul, MN, 55108, USA

    Randall S. Singer

  3. Franklin and Marshall College, PO Box 3003, Lancaster, PA, 17604, USA

    Elizabeth V. Lonsdorf

  4. Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S 2nd St, Minneapolis, MN, 55454, USA

    Richard Maclehose

  5. Emory University and Rollins School of Public Health, 400 Dowman Drive, Math and Science Center, Suite E510, Atlanta, GA, 30322, USA

    Thomas R. Gillespie

  6. Gombe Stream Research Center, Jane Goodall Institute, PO Box 1182, Kigoma, Tanzania

    Iddi Lipende, Shadrack Kamenya & Deus Mjungu

  7. Gombe National Park, Tanzania National Parks Authority, S L P 185, Kigoma, Tanzania

    Jane Raphael

  8. Zoological Pathology Program, University of Illinois, 3300 Golf Rd, Brookfield, IL, 60513, USA

    Karen Terio

  9. George Washington University, 800 22nd St. NW, Suite 6000, Washington, DC, 20052, USA

    Carson Murray

  10. Duke University, Box 90383, Durham, NC, 27708, USA

    Anne Pusey

  11. Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104, USA

    Beatrice H. Hahn

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  1. Tiffany M. Wolf
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  2. Randall S. Singer
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  9. Carson Murray
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  12. Shadrack Kamenya
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  13. Deus Mjungu
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  14. Dominic A. Travis
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Correspondence to Tiffany M. Wolf.

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Wolf, T.M., Singer, R.S., Lonsdorf, E.V. et al. Syndromic Surveillance of Respiratory Disease in Free-Living Chimpanzees. EcoHealth 16, 275–286 (2019). https://doi.org/10.1007/s10393-019-01400-y

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  • DOI: https://doi.org/10.1007/s10393-019-01400-y

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