Abstract
Aim
The effect of the COVID-19 pandemic on the mental health of children and adolescents is a major challenge in public health. Due to the importance of the problem the current study aimed to investigate the global prevalence of anxiety, depression, and post-traumatic stress disorder symptoms in children and adolescents during the COVID-19 pandemic.
Subject and methods
This study followed the PRISMA guidelines and searched online databases (PubMed, Scopus, and Web of Science) for observational studies published from January 2020 to December 2022 which determine the prevalence of anxiety, depression, and post-traumatic stress disorder symptoms in children and adolescents (age ≤18 years) during the COVID-19 pandemic.
Results
Overall, 23.8% (95% CI 21.5–26.1; P < 0.001, I2 = 99.8) had at least one psychological disorder. North America 40.7% (95% CI 33.2-48.3; P < 0.001, I2 = 95.3) had the highest, and East Asia 20.2% (95% CI 17.4-22.9; P < 0.001, I2 = 97.6) had the lowest prevalence of psychological disorders. The pooled prevalence of anxiety, depression, and PTSD was 26%, 23%, and 23%, respectively. The highest prevalence of anxiety was seen in Europe (43.2% (95% CI 16.9–69.6; P < 0.001, I2 = 98.6)), depression in North America (35.4 % (95% CI 29.8-41)) and PTSD in Central and South America (60.3% (95% CI 57-63.6)) respectively.
Conclusion
Considering the high prevalence of psychological disorders caused by the COVID-19 pandemic among children and adolescents, it is necessary to consider public health interventions to prevent its long-term effects.
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Data availability
All data are available in the manuscript.
Code availability
Not applicable.
References
Abawi O, Welling MS, van den Eynde E et al (2020) COVID-19 related anxiety in children and adolescents with severe obesity: A mixed-methods study. Clinical Obesity 10:e12412
Ahmed IS, Tapponi SL, Widatallah ME, Alakkad YM, Haider M (2023) Unmasking the enigma: An in-depth analysis of COVID-19 impact on the pediatric population. J Infect Public Health 16:1346–1360
Alqassim A-Y, Mahfouz M-S, Hakami M-M et al (2022) Depression, Anxiety, Stress and Their Association with the Use of Electronic Devices among Adolescents during the COVID-19 Pandemic. Int J Mental Health Prom 24:251–262
Arsenault C, Gage A, Kim M, Kapoor K et al (2022) COVID-19 and resilience of healthcare systems in ten countries. Nat Med 28:1314–1324
Brazendale K, Beets MW, Weaver RG et al (2017) Understanding differences between summer vs school obesogenic behaviors of children: the structured days hypothesis. Int J Behav Nutr Phys Act 14:100
Brooks SK, Smith LE, Webster RK, et al (2020) The impact of unplanned school closure on children's social contact: rapid evidence review. Euro Surveill 25
Cao C, Wang L, Fang R, et al (2022) 9J Affect Disorders 296, 126-129.
Chen S, Cheng Z, Wu J (2020) Risk factors for adolescents’ mental health during the COVID-19 pandemic: a comparison between Wuhan and other urban areas in China. Glob Health 16:1–11
Chen Y, Zhu Z, Lei F, Lei S, Chen J (2021) Prevalence and risk factors of post-traumatic stress disorder symptoms in students aged 8–18 in Wuhan, China 6 months after the control of COVID-19. Front Psychol 12:740575
Crawley E, Loades M, Feder G et al (2020) Wider collateral damage to children in the UK because of the social distancing measures designed to reduce the impact of COVID-19 in adults. BMJ Paediatr Open 4:e000701
Cucinotta D, Vanelli M (2020) WHO Declares COVID-19 a Pandemic. Acta Biomed 91:157–160
Dalton L, Rapa E, Stein A (2020) Protecting the psychological health of children through effective communication about COVID-19. Lancet Child Adolesc Health 4:346–347
Davico C, Ghiggia A, Marcotulli D, Ricci F, Amianto F, Vitiello B (2021) Psychological impact of the COVID-19 pandemic on adults and their children in Italy. Front Psychiatry 12:572997
Deng J, Zhou F, Hou W et al (2023) Prevalence of mental health symptoms in children and adolescents during the COVID-19 pandemic: A meta-analysis. Ann N Y Acad Sci 1520:53–73
Duan L, Shao X, Wang Y et al (2020) An investigation of mental health status of children and adolescents in china during the outbreak of COVID-19. J Affect Disorders 275:112–118
Fernandez-Canani MA, Burga-Cachay SC, Valladares-Garrido MJ (2022) Association between Family Dysfunction and Post-Traumatic Stress Disorder in School Students during the Second COVID-19 Epidemic Wave in Peru. Int J Environ Res Public Health 30 19(15):9343. https://doi.org/10.3390/ijerph19159343
Figas K, Giannouchos TV, Crouch E (2023) Child and Adolescent Anxiety and Depression Prior to and During the COVID-19 Pandemic in the United States. Child Psychiatry Hum Dev:1-11.
Garcia de Avila MA, Hamamoto Filho PT, Jacob FL d S, Alcantara LRS, Berghammer M, Jenholt Nolbris M, Olaya-Contreras P, Nilsson S (2020) Children’s anxiety and factors related to the COVID-19 pandemic: An exploratory study using the children’s anxiety questionnaire and the numerical rating scale. Int J Environ Res Public Health 17:5757
Golberstein E, Wen H, Miller BF (2020) Coronavirus Disease 2019 (COVID-19) and Mental Health for Children and Adolescents. JAMA Pediatr 174:819–820
Grewenig E, Lergetporer P, Werner K, Woessmann L, Zierow L (2021) COVID-19 and educational inequality: How school closures affect low- and high-achieving students. Eur Econ Rev 140:103920
Guessoum SB, Lachal J, Radjack R et al (2020) Adolescent psychiatric disorders during the COVID-19 pandemic and lockdown. Psychiatry Res 291:113264
Harrison L, Carducci B, Klein JD, Bhutta ZA (2022) Indirect effects of COVID-19 on child and adolescent mental health: an overview of systematic reviews. BMJ Glob Health 7
He Y, Li X, Zhao J, An Y (2021) Family resilience, media exposure, and children’s mental health in China during COVID-19. Fam J 30:4. https://doi.org/10.1177/10664807211061832
Hu T, Wang Y, Lin L, Tang W (2021) The mediating role of daytime sleepiness between problematic smartphone use and post-traumatic symptoms in COVID-19 home-refined adolescents. Child Youth Services Rev 126:106012
Imran N, Zeshan M, Pervaiz Z (2020) Mental health considerations for children & adolescents in COVID-19 Pandemic. Pak J Med Sci 36:S67–S72
Karbasi Z, Eslami P (2022) Prevalence of post-traumatic stress disorder during the COVID-19 pandemic in children: a review and suggested solutions. Middle East Curr Psychiatry 29(1):74. https://doi.org/10.1186/s43045-022-00240-x
Kaufman KR, Petkova E, Bhui KS, Schulze TG (2020) A global needs assessment in times of a global crisis: world psychiatry response to the COVID-19 pandemic. BJPsych Open 6:e48
Kessler RC, Amminger GP, Aguilar-Gaxiola S, Alonso J, Lee S, Ustün TB (2007) Age of onset of mental disorders: a review of recent literature. Curr Opin Psychiatry 20:359–364
Kianfar N, Mesgari MS (2022) GIS-based spatio-temporal analysis and modeling of COVID-19 incidence rates in Europe. Spat Spatiotemporal Epidemiol 41:100498
Kılınçel Ş, Kılınçel O, Muratdağı G, Aydın A, Usta MB (2021) Factors affecting the anxiety levels of adolescents in home-quarantine during COVID-19 pandemic in Turkey. Asia-Pacific Psychiat 13:e12406
Kleine R, Galimov A, Hanewinkel R, Unger J, Sussman S, Hansen J (2023) Impact of the COVID-19 pandemic on young people with and without pre-existing mental health problems. Scientific Reports 13:6111
Kola L, Kohrt BA, Hanlon C et al (2021) COVID-19 mental health impact and responses in low-income and middle-income countries: reimagining global mental health. Lancet Psychiat 8:535–550
Krass P, Zimbrick-Rogers C, Iheagwara C, Ford CA, Calderoni M (2020) COVID-19 outbreak among adolescents at an inpatient behavioral health hospital. J Adolescent Health 67:612–614
Lee J (2020) Mental health effects of school closures during COVID-19. Lancet Child Adolesc Health 4:421
Li W, Zhang Y, Wang J, Ozaki A, Wang Q, Chen Y, Jiang Q (2021) Association of home quarantine and mental health among teenagers in Wuhan, China, during the COVID-19 pandemic. JAMA Pediatr 175(3):313–316. https://doi.org/10.1001/jamapediatrics.2020.5499
Li Y, Duan W, Chen Z (2020) Latent profiles of the comorbidity of the symptoms for posttraumatic stress disorder and generalized anxiety disorder among children and adolescents who are susceptible to COVID-19. Child Youth Services Rev 116:105235
Liu F, Zhou N, Cao H et al (2017) Chinese college freshmen's mental health problems and their subsequent help-seeking behaviors: A cohort design (2005-2011). PLoS One 12:e0185531
Lo CK-L, Mertz D, Loeb M (2014) Newcastle-Ottawa Scale: comparing reviewers’ to authors’ assessments. BMC Med Res Methodol 14:45
Ma L, Mazidi M, Li K et al (2021a) Prevalence of mental health problems among children and adolescents during the COVID-19 pandemic: A systematic review and meta-analysis. J Affect Disord 293:78–89
Ma Z, IdrisS ZY et al (2021b) The impact of COVID-19 pandemic outbreak on education and mental health of Chinese children aged 7–15 years: an online survey. BMC Pediat 21:1–8
Madigan S, Racine N, Vaillancourt T et al (2023) Changes in Depression and Anxiety Among Children and Adolescents From Before to During the COVID-19 Pandemic: A Systematic Review and Meta-analysis. JAMA Pediatr 177:567–581
McKune SL, Acosta D, Diaz N et al (2021) Psychosocial health of school-aged children during the initial COVID-19 safer-at-home school mandates in Florida: a cross-sectional study. BMC Public Health 21:1–11
Meherali S, Punjani N, Louie-Poon S et al (2021) Mental Health of Children and Adolescents Amidst COVID-19 and Past Pandemics: A Rapid Systematic Review Int J Environ Res Public Health 18
Mensi MM, Capone L, Rogantini C et al (2021) COVID-19-related psychiatric impact on Italian adolescent population: A cross-sectional cohort study. J Commun Psychol 49:1457–1469
Mude W, Oguoma VM, Nyanhanda T, Mwanri L, Njue C (2021) Racial disparities in COVID-19 pandemic cases, hospitalisations, and deaths: A systematic review and meta-analysis. J Glob Health 11:05015
Murata S, Rezeppa T, Thoma B et al (2021) The psychiatric sequelae of the COVID-19 pandemic in adolescents, adults, and health care workers. Depress Anxiety 38:233–246
Oliveira JMD, Butini L, Pauletto P et al (2022) Mental health effects prevalence in children and adolescents during the COVID-19 pandemic: A systematic review. Worldviews Evid Based Nurs 19:130–137
Oosterhoff B, Palmer CA, Wilson J, Shook N (2020) Adolescents' Motivations to Engage in Social Distancing During the COVID-19 Pandemic: Associations With Mental and Social Health. J Adolesc Health 67:179–185
Pasquale S, Gregorio GL, Caterina A, et al (2021) COVID-19 in Low- and Middle-Income Countries (LMICs): A Narrative Review from Prevention to Vaccination Strategy. Vaccines (Basel) 9
Pisano S, Catone G, Gritti AA (2021) Emotional symptoms and their related factors in adolescents during the acute phase of Covid-19 outbreak in South Italy. Italian J Pediat 47:1–8
Pizarro-Ruiz JP, Ordóñez-Camblor N (2021) Effects of Covid-19 confinement on the mental health of children and adolescents in Spain. Sci Rep 11(1):11713. https://doi.org/10.1038/s41598-021-91299-9
Polanczyk GV, Salum GA, Sugaya LS, Caye A, Rohde LA (2015) Annual research review: A meta-analysis of the worldwide prevalence of mental disorders in children and adolescents. J Child Psychol Psychiatry 56:345–365
Raony Í, de Figueiredo CS, Pandolfo P et al (2020) Psycho-Neuroendocrine-Immune Interactions in COVID-19: Potential Impacts on Mental Health. Front Immunol 11:1170
Salanti G, Peter N, Tonia T et al (2022) The Impact of the COVID-19 Pandemic and Associated Control Measures on the Mental Health of the General Population : A Systematic Review and Dose-Response Meta-analysis. Ann Intern Med 175:1560–1571
Sama BK, Kaur P, Thind PS et al (2021) Implications of COVID-19-induced nationwide lockdown on children's behaviour in Punjab, India. Child: Care Health Dev 47:128–135
Sayed MH, Hegazi MA, El-Baz MS, Alahmadi TS et al (2021) COVID-19 related posttraumatic stress disorder in children and adolescents in Saudi Arabia. PLoS One 16:e0255440
Segre G, Campi R, Scarpellini F et al (2021) Interviewing children: the impact of the COVID-19 quarantine on children’s perceived psychological distress and changes in routine. BMC Pediat 21:1–11
Selçuk EB, Demir A, Erbay LG et al (2021) Anxiety, depression and post-traumatic stress disorder symptoms in adolescents during the COVID-19 outbreak and associated factors. Int J Clin Pract 75:e14880
Shek DT, Zhao L, Dou D, Zhu X, Xiao C (2021) The impact of positive youth development attributes on posttraumatic stress disorder symptoms among Chinese adolescents under COVID-19. J Adolescent Health 68:676–682
Smetana JG, Campione-Barr N, Metzger A (2006) Adolescent development in interpersonal and societal contexts. Annu Rev Psychol 57:255–284
Song M (2020) Psychological stress responses to COVID-19 and adaptive strategies in China. World Dev 136:105107
Subramaniam M, Abdin E, Picco L et al (2017) Stigma towards people with mental disorders and its components - a perspective from multi-ethnic Singapore. Epidemiol Psychiatr Sci 26:371–382
Tang S, Xiang M, Cheung T, Xiang Y-T (2021) Mental health and its correlates among children and adolescents during COVID-19 school closure: The importance of parent-child discussion. J Affect Disorders 279:353–360
Taskesen B, Kardas O, Yılmaz K (2023) Evaluation of depression, anxiety and posttraumatic stress response levels of children and adolescents treated with COVID-19. Eur J Pediatr 182:567–574
Thomeer MB, Moody MD, Yahirun J (2023) Racial and Ethnic Disparities in Mental Health and Mental Health Care During The COVID-1 Pandemic 9. J Racial Ethn Health Disparities 10:961–976
Wang G, Zhang Y, Zhao J, Zhang J, Jiang F (2020a) Mitigate the effects of home confinement on children during the COVID-19 outbreak. Lancet 395:945–947
Wang G, Zhang Y, Zhao J, Zhang J, Jiang F (2020b) Mitigate the effects of home confinement on children during the COVID-19 outbreak. Lancet 395:945–947
Wang J, Wang H, Lin H et al (2021) Study problems and depressive symptoms in adolescents during the COVID-19 outbreak: poor parent-child relationship as a vulnerability. Glob Health 17:1–9
Wen F, Meng Y, Liu K et al (2023) Depression among schoolchildren and adolescents aged 9-17 years during the outbreak of COVID-19 in Beijing: a cross-sectional online survey. Psychol Health Med 28:148–160
Xie X, Xue Q, Zhou Y, Zhu K, Liu Q, Zhang J et al (2020) Mental health status among children in home confinement during the coronavirus disease 2019 outbreak in Hubei Province, China. JAMA Pediatr 174(9):898–900
Xie X, Liu Q, Zhu K et al (2022) Psychological Symptom Progression in School-Aged Children After COVID-19 Home Confinement: A Longitudinal Study. Front Psychiat 13:809107
Xu Z, Huang F, Kösters M, Rüsch N (2017) Challenging mental health related stigma in China: Systematic review and meta-analysis II Interventions among people with mental illness. Psychiatry Res 255:457–464
Xu H, Zhang H, Huang L et al (2021) Increased symptoms of post-traumatic stress in school students soon after the start of the COVID-19 outbreak in China. BMC Psychiat 21:330
Yu M, Cheng S, Fung K P, Wong J P, Jia C (2022) More than Mental Illness: Experiences of Associating with Stigma of Mental Illness for Chinese College Students Int J Environ Res Public Health 19
Yue J, Zang X, Le Y, An Y (2022) Anxiety, depression and PTSD among children and their parent during 2019 novel coronavirus disease (COVID-19) outbreak in China. Curr Psychol 41:5723–5730
Zhang Z, Sun K, Jatchavala C, et al (2019) Overview of Stigma against Psychiatric Illnesses and Advancements of Anti-Stigma Activities in Six Asian Societies. Int J Environ Res Public Health 17
Zhang C, Ye M, Fu Y, Yang M, Luo F, Yuan J, Tao Q (2020a) The psychological impact of the COVID-19 pandemic on teenagers in China. J Adolescent Health 67:747–755
Zhang L, Zhang D, Fang J, Wan Y, Tao F, Sun Y(2020b) Assessment of mental health of Chinese primary school students before and after school closing and opening during the COVID-19 pandemic. JAMA Network Open 3(9):e2021482-e
Zhang Y, Zhuang LY, Yang W (2020c) Survey of symptoms of post-traumatic stress disorder in middle school students during the COVID-19 pandemic: taking Chengdu Shude Middle School as an example. Educ Sci Forum 17:45–48
Zhou S-J, Zhang L-G, Wang L-L et al (2020) Prevalence and socio-demographic correlates of psychological health problems in Chinese adolescents during the outbreak of COVID-19. Eur Child Adolescent Psychiat 29:749–758
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YA and SA conception of the idea, data analysis, manuscript writing. Sh Sh and MS: searching, data extraction, manuscript writing. All authors read and approved the final manuscript.
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Alizadeh, S., Shahrousvand, S., Sepandi, M. et al. Prevalence of anxiety, depression and post-traumatic stress disorder symptoms in children and adolescents during the COVID-19 pandemic: A systematic review and meta-analysis. J Public Health (Berl.) (2023). https://doi.org/10.1007/s10389-023-02168-w
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DOI: https://doi.org/10.1007/s10389-023-02168-w