Abstract
Aim
In this study, we compared attitudes toward vaccination and fear of coronavirus disease (COVID-19) between patients with severe mental illness (SMI) and a control group.
Subject and methods
This study performed at a community mental health center included 136 patients with SMI and 105 healthy controls. A sociodemographic data form, the Clinical Global Impression Scale, COVID-19 Phobia Scale, Perception of Causes of COVID-19 Scale, and Attitudes Toward the COVID-19 Vaccine Scale were administered.
Results
Both groups showed similar vaccination rates, attitudes toward the COVID-19 vaccine, and fear of COVID-19. We observed an intergroup difference in the belief subdimension of the Perception of Causes of COVID-19 Scale; however, the other subscale scores were similar. Patients’ perceived risk of contracting COVID-19 was lower than that of the control group. In contrast to this finding, the rates of infection were higher in patients.
Conclusions
Considering the limited number of studies that have investigated the attitudes of patients with SMI toward vaccination, we observed that in contrast to the findings of previous studies, vaccination rates were similar between the SMI and control groups during the pandemic in Turkey. However, we observed an intergroup difference in factors that affected unwillingness to get vaccinated during the early period despite eligibility and availability of the vaccine. We conclude that interventions required for individuals with SMI differ from those required for healthy individuals.
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Data availability
The data that support the findings of this study are available from the corresponding author.
References
Akarsu B, Özdemir DC, Başer DA, Fidancı İ, Aksoy H, Cankurtaran M (2020) COVID-19 aşı araştırmaları devam ederken; Toplumun gelecekteki COVID-19 aşısına yönelik düşünce ve tutumları. 19. Ulusal Aile Hekimliği Kongresi 29:105–107
Barcella CA, Polcwiartek C, Mohr GH, Hodges G, Søndergaard K, Bang N et al (2021) Severe mental illness is associated with increased mortality and severe course of COVID-19. Acta Psychiatr Scand 144:82–91. https://doi.org/10.1111/acps.13309
Basar K (2021) Vaccination and mental illness: the role of mental health professionals. Turk J Psychiatry 32:A5–A6. https://doi.org/10.5080/u27029
Bitan DT, Kridin K, Cohen AD, Weinstein O (2021) COVID-19 hospitalisation, mortality, vaccination, and postvaccination trends among people with schizophrenia in Israel: a longitudinal cohort study. Lancet Psychiatry 8:901–908. https://doi.org/10.1016/S2215-0366(21)00256-X
Cansel N, Unal A, Onsoz SE, Akan M, Erbay LG, Melez SNI (2021) Frequency and predictors of coronavirus anxiety in psychiatric patients and healthy people and its effect on treatment compliance during the pandemic. Medicine 10:1433–1440. https://doi.org/10.5455/medscience.2021.03.07.241
Caserotti M, Girardi P, Rubaltelli E, Tasso A, Lotto L, Gavaruzzi T (2021) Associations of COVID-19 risk perception with vaccine hesitancy over time for Italian residents. Soc Sci Med 272:113688. https://doi.org/10.1016/j.socscimed.2021.113688
Curtis HJ, Inglesby P, Morton CE, MacKenna B, Green A, Hulme W et al. (The OpenSAFELY Collaborative) (2021). Trends and clinical characteristics of COVID-19 vaccine recipients: a federated analysis of 57.9 million patients’ primary care records in situ using OpenSAFELY. Br J Gen Pract 72(714):e51–e62. https://doi.org/10.3399/BJGP.2021.0376. Erratum in: Br J Gen Pract. 2022 Feb 24;72(716):106
Danenberg R, Shemesh S, Bitan DT, Maoz H, Saker T, Dror C et al (2021) Attitudes of patients with severe mental illness towards COVID-19 vaccinations: a preliminary report from a public psychiatric hospital. J Psychiatr Res 143:16–20 https://doi.org/10.1016/j.jpsychires.2021.08.020
De Hert M, Mazereel V, Stroobants M, De Picker L, Van Assche K, Detraux J (2021) COVID-19-related mortality risk in people with severe mental illness: a systematic and critical review. Front Psychiatry 12:798554. https://doi.org/10.3389/fpsyt.2021.798554
Dilbaz N, Noyan OC, Alpar G, Kazan OK (2020) Development of the COVID-19 Phobia Scale: validity and reliability study. J Neurobehav Sci 7:142. https://doi.org/10.4103/jnbs.jnbs_27_20
Druss BG (2020) Addressing the COVID-19 pandemic in populations with serious mental illness. JAMA Psychiatry 77:891–892. https://doi.org/10.1001/jamapsychiatry.2020.0894
Fond G, Nemani K, Etchecopar-Etchart D, Loundou A, Goff DC, Lee SW et al (2021) Association between mental health disorders and mortality among patients with COVID-19 in 7 countries: a systematic review and meta-analysis. JAMA Psychiatry 78:1208–1217. https://doi.org/10.1001/jamapsychiatry.2021.2274
Geniş B, Gürhan N, Koç M, Geniş Ç, Şirin B, Çırakoğlu O et al (2020) Development of perception and attitude scales related with COVID-19 pandemia. Pearson J Soc Sci-Humans 5:306–328. https://doi.org/10.46872/pj.127
Goldberger N, Bergman-Levy T, Haklai Z, Yoffe R, Davidson M, Susser E et al (2022) COVID-19 and severe mental illness in Israel: testing, infection, hospitalization, mortality and vaccination rates in a countrywide study. Mol Psychiatry 27:3107–3114. https://doi.org/10.1038/s41380-022-01562-2
González-Blanco L, Dal Santo F, García-Álvarez L, de la Fuente-Tomás L, Lacasa CM, Paniagua G et al (2020) COVID-19 lockdown in people with severe mental disorders in Spain: Do they have a specific psychological reaction compared with other mental disorders and healthy controls? Schizophr Res 223:192–198. https://doi.org/10.1016/j.schres.2020.07.018
Guy W (1976) Clinical global impressions. ECDEU Assessment Manual for Psychopharmacology, revised (DHEW Publ. No. ADM 76-338).National Institute of Mental Health, Rockville, MD, USA, pp 217–222
Hao F, Tan W, Jiang L, Zhang L, Zhao X, Zou Y et al (2020) Do psychiatric patients experience more psychiatric symptoms during COVID-19 pandemic and lockdown? A case-control study with service and research implications for immunopsychiatry. Brain Behav Immun 87:100–106. https://doi.org/10.1016/j.bbi.2020.04.069
Hao F, Wang B, Tan W, Husain SF, McIntyre RS, Tang X et al (2021) Attitudes toward COVID-19 vaccination and willingness to pay: comparison of people with and without mental disorders in China. BJPsych Open 7:e146. https://doi.org/10.1192/bjo.2021.979
Huang H, Zhu X-M, Liang P-W, Fang Z-M, Luo W, Ma Y-M et al (2021) COVID-19 vaccine uptake, acceptance, and hesitancy among persons with mental disorders during the second stage of China's nationwide vaccine rollout. Front Med 8:761601. https://doi.org/10.3389/fmed.2021.761601
Iasevoli F, Fornaro M, D'Urso G, Galletta D, Casella C, Paternoster M et al (2021) Psychological distress in patients with serious mental illness during the COVID-19 outbreak and one-month mass quarantine in Italy. Psychol Med 51:1054–1056. https://doi.org/10.1017/S0033291720001841
Jefsen OH, Kølbæk P, Gil Y, Speed M, Dinesen PT, Sønderskov KM et al (2021) COVID-19 vaccine willingness amongst patients with mental illness compared with the general population. Acta Neuropsychiatr 33:273–276. https://doi.org/10.1017/neu.2021.15
Karabela ŞN, Coşkun F, Hoşgör H (2021) Investigation of the relationships between perceived causes of COVID-19, attitudes towards vaccine and level of trust in information sources from the perspective of Infodemic: the case of Turkey. BMC Public Health 21:1–12. https://doi.org/10.1186/s12889-021-11262-1
Karlsson LC, Soveri A, Lewandowsky S, Karlsson L, Karlsson H, Nolvi S et al (2021) Fearing the disease or the vaccine: The case of COVID-19. Person Individ Differ 172:110590. https://doi.org/10.1016/j.paid.2020.110590
Kavoor AR (2020) COVID-19 in people with mental illness: challenges and vulnerabilities. Asian J Psychiatry 51:102051. https://doi.org/10.1016/j.ajp.2020.102051
Kirk RE (2008) Statistics: an introduction, 5th edn. Thompson/Wadsworth, Belmont
Mazereel V, Vanbrabant T, Desplenter F, Detraux J, De Picker L, Thys E et al (2021) COVID-19 vaccination rates in a cohort study of patients with mental illness in residential and community care. Front Psychiatry 12:805528. https://doi.org/10.3389/fpsyt.2021.805528
Mohan M, Perry BI, Saravanan P, Singh SP (2021) COVID-19 in people with schizophrenia: potential mechanisms linking schizophrenia to poor prognosis. Front Psychiatry 12:666067. https://doi.org/10.3389/fpsyt.2021.666067
Mondal P, Sinharoy A, Su L (2021) Sociodemographic predictors of COVID-19 vaccine acceptance: a nationwide US-based survey study. Public Health 198:252–259. https://doi.org/10.1016/j.puhe.2021.07.028
Muruganandam P, Neelamegam S, Menon V, Alexander J, Chaturvedi SK (2020) COVID-19 and severe mental illness: impact on patients and its relation with their awareness about COVID-19. Psychiatry Res 291:113265. https://doi.org/10.1016/j.psychres.2020.113265
Nam S-H, Nam J-H, Kwon C-Y (2021) Comparison of the mental health impact of COVID-19 on vulnerable and non-vulnerable groups: a systematic review and meta-analysis of observational studies. Int J Environ Res Public Health 18:10830. https://doi.org/10.3390/ijerph182010830
Natale A, Concerto C, Rodolico A, Birgillito A, Bonelli M, Martinez M et al (2022) Risk perception among psychiatric patients during the COVID-19 pandemic. Int J Environ Res Public Health 19:2620. https://doi.org/10.3390/ijerph19052620
Nazlı ŞB, Yığman F, Sevindik M, Deniz Özturan D (2022) Psychological factors affecting COVID-19 vaccine hesitancy. Irish J Med Sci 191:71–80. https://doi.org/10.1007/s11845-021-02640-0
Özmen S, Özkan O, Özer Ö, Yanardağ MZ (2021) Investigation of COVID-19 fear, well-being and life satisfaction in Turkish society. Soc Work Public Health 36(2):164–177
Pandolfo G, Genovese G, Iannuzzo F, Bruno A, Pioggia G, Gangemi S (2022) COVID-19 vaccination and mental disorders, what has been accomplished and future direction. Brain Sci 12:292 https://doi.org/10.3390/brainsci12020292
Pardamean E, Roan W, Iskandar KTA, Prayangga R, Hariyanto TI (2022) Mortality from coronavirus disease 2019 (Covid-19) in patients with schizophrenia: a systematic review, meta-analysis and meta-regression. Gen Hosp Psychiatry 75:61–67. https://doi.org/10.1016/j.genhosppsych.2022.01.010
Ren X, Shen F, Gui Y, Wang W, Xing B, Huang W (2021) The attitudes of psychiatric patients towards COVID-19 vaccination in China: a cross-sectional study. BMC Psychiatry 21:1–10. https://doi.org/10.1186/s12888-021-03484-9
Salali GD, Uysal MS (2020) COVID-19 vaccine hesitancy is associated with beliefs on the origin of the novel coronavirus in the UK and Turkey. Psychol Med 52:1–3. https://doi.org/10.1017/S0033291720004067
Satici B, Saricali M, Satici SA, Griffiths MD (2020) Intolerance of uncertainty and mental wellbeing: serial mediation by rumination and fear of COVID-19. Int J Ment Health Addict 20:2731–2742. https://doi.org/10.1007/s11469-020-00305-0
Satici B, Gocet-Tekin E, Deniz M, Satici SA (2021) Adaptation of the Fear of COVID-19 Scale: Its association with psychological distress and life satisfaction in Turkey. Int J Ment Health Addict 19:1980–1988. https://doi.org/10.1007/s11469-020-00294-0
Solé B, Verdolini N, Amoretti S, Montejo L, Rosa AR, Hogg B et al (2021) Effects of the COVID-19 pandemic and lockdown in Spain: comparison between community controls and patients with a psychiatric disorder. Preliminary results from the BRIS-MHC STUDY. J Affect Disord 281:13–23. https://doi.org/10.1016/j.jad.2020.11.099
Türkoğlu MC, Yılmaz FK (2021) Sağlık Politikası Analizi: Türkiye’de Covid-19 Pandemi Döneminde Uygulanan Sağlık Politikaları. Toplumsal Politika Dergisi 2(1):11–29
Vu TS, Le MA, Huynh NTV, Truong L, Vu GT, Nguyen LH (2021) Towards efficacy and sustainability of global, regional and national COVID-19 vaccination programs. J Glob Health 11:03099. https://doi.org/10.7189/jogh.11.03099
Acknowledgements
The authors thank all the participants who participated in the study. We would like to thank Editage [http://www.editage.com] for editing and reviewing this manuscript for English language. We also would like to thank Mehmet Sata for his valuable help with regard to statistical analysis of this manuscript.
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All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Ayse Gokcen Gundogmus, Selma Ercan Dogu and Gamze Zengin Ispir. The first draft of the manuscript was written by Ayse Gokcen Gundogmus, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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An ethical approval letter from the Clinical Research Ethics Committee of the University of Health Sciences, Ankara Diskapi Yildirim Beyazit Training and Research Hospital with reference no (129/02, Date: 24.01.2022) was obtained. Before data collection, all participants gave their written informed consent. The confidentiality of the study participants’ related data was maintained by avoiding using possible identifiers.
Ethics approval
The study was approved by the Clinical Research Ethics Committee of the Health Sciences University Diskapi Yildirim Beyazit Training and Research Hospital (Date: 24.01.2022 — Number: 129/02).
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All participants provided written informed consent before participating in the study.
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Gundogmus, A.G., Ercan Dogu, S. & Zengin Ispir, G. Comparison of attitudes toward the coronavirus disease vaccine, fear of coronavirus disease, and perception regarding causes of coronavirus disease between patients with serious mental illness and healthy controls. J Public Health (Berl.) (2023). https://doi.org/10.1007/s10389-023-02019-8
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DOI: https://doi.org/10.1007/s10389-023-02019-8