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The effect of chlorhexidine on glycemic and inflammation control in children with type 1 diabetes mellitus

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A Publisher Correction to this article was published on 30 January 2018

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Abstract

Aims

The aim of this study was to evaluate the effect of chlorhexidine 0.12% in periodontal parameters of dental plaque indices and gingival indices and in the glycemic control in children with type 1 diabetes mellitus (DM).

Methods

This crossover study was carried in two stages within a 6-month gap between them. We selected 16 volunteers with type 1 DM (aged from 6 to 14 years). These patients were randomly divided in two groups: group 1 (oral hygiene instruction; chlorhexidine 0.12% mouth rinse for 15 days); group 2 (oral hygiene instruction). In the second stage, the patients changed the groups. All patients received basic periodontal treatment and instruction to perform buccal hygiene using the scrubbing technique. After 3 and 6 months, the patients were instructed again and they received a periodontal maintenance therapy. The evaluation of periodontal parameters (dental plaque indices and gingival indices) and glycemic control (glycemic measures through fasting blood glucose levels and glycated hemoglobin levels - HbA1c) was carried out from 0, 3 and 6 months.

Results

Considering all parameters, only plaque indices presented a significant reduction after 6 months in group 1 and after 3 months in group 2, if compared with initial values. The groups did not present significant differences between them in all the assessed parameters.

Conclusion

The chlorhexidine solution did not provide benefits for periodontal parameters and for the glycemic control in children with type 1DM.

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Change history

  • 30 January 2018

    The journal had been advised to revise the title so that Clarivate Analytics can try to count the citations more accurately. There’s been confusion due to the existence of another journal with the same name.

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Correspondence to Adriano Tomio Hoshi.

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Conflict of interest and sources of funding statement

The authors declare that there are no conflicts of interest in this study. This study was supported by the University of the State of Western Parana, Cascavel, Paraná, Brazil.

Additional information

The original version of this article was revised: Due to the existence of another journal with the same name, the Publisher has added a subtitle, “From Theory to Practice.” Effective as of January 2018, the new title of this Journal is Journal of Public Health: From Theory to Practice.

A correction to this article is available online at https://doi.org/10.1007/s10389-017-0893-1.

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Hoshi, A.T., Steffen, P., Pawlak, L.C. et al. The effect of chlorhexidine on glycemic and inflammation control in children with type 1 diabetes mellitus. J Public Health 26, 23–28 (2018). https://doi.org/10.1007/s10389-017-0842-z

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  • DOI: https://doi.org/10.1007/s10389-017-0842-z

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