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Outer retinal microstructure and visual function after macular hole surgery with and without Brilliant Blue G

  • Clinical Investigation
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A Publisher Correction to this article was published on 03 November 2022

This article has been updated

Abstract

Purpose

To evaluate the outer retinal microstructure and visual function after idiopathic macular hole (MH) surgery using internal limiting membrane (ILM) peeling with and without Brilliant Blue G (BBG) staining.

Study design

Retrospective, consecutive case series.

Methods

A total of 49 eyes of 47 patients were enrolled: 23 eyes of 23 patients with MH who underwent ILM peeling without dyes (control group) and 26 eyes of 26 patients who underwent BBG staining (BBG group). The lengths of defects of the photoreceptor ellipsoid zone (EZ), external limiting membrane (ELM), and interdigitation zone (IZ) were measured.

Results

The rate of MH closure after initial surgery was 95.6% (22/23 eyes) for the control group versus 100% (26/26 eyes) for the BBG group. In the 48 eyes with MH closure, the recovery rate of ELM deficiency and change in IZ deficiency showed no difference between the groups. The changes in EZ deficiency at 1 and 12 months were greater in the BBG group than in the control group. (P = 0.047 and 0.031). Visual acuity was better in the BBG group than in the control group during 12 months postoperatively (P < 0.001—0.038).

Conclusion

Eyes undergoing BBG-assisted MH surgery achieved faster recovery of the outer retinal structures and greater visual improvement than those of eyes without BBG.

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Authors and Affiliations

  1. Department of Ophthalmology, Teikyo University School of Medicine, University Hospital Mizonokuchi, 5-1-1, Futago, Takatsu-ku, Kawasaki, Kanagawa, 213-8507, Japan

    Yuko Komiya, Asuka Takeyama, Masaki Shibata, Yutaka Imamura & Masahiro Ishida

  2. Department of Ophthalmology, Toho University Ohashi Medical Center, 2-22-36, Ohashi, Meguro-ku, Tokyo, 153-8515, Japan

    Asuka Takeyama & Masahiro Ishida

Authors
  1. Yuko Komiya
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  2. Asuka Takeyama
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  3. Masaki Shibata
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  4. Yutaka Imamura
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  5. Masahiro Ishida
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Corresponding author

Correspondence to Asuka Takeyama.

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Conflict of interest

Y. Komiya, None; A. Takeyama, None; M. Shibata, None; Y. Imamura, None; M. Ishida, None.

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Corresponding Author: Asuka Takeyama

The original publication has been corrected for revision in Table 3 and Figure 3

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Komiya, Y., Takeyama, A., Shibata, M. et al. Outer retinal microstructure and visual function after macular hole surgery with and without Brilliant Blue G. Jpn J Ophthalmol 66, 534–540 (2022). https://doi.org/10.1007/s10384-022-00942-z

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  • DOI: https://doi.org/10.1007/s10384-022-00942-z

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