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Astigmatism profile in the elderly population: Tehran Geriatric Eye Study

  • Clinical Investigation
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Abstract

Purpose

To determine the prevalence of astigmatism and its associated factors and examine astigmatism symmetry patterns in an elderly population.

Study design

Population based cross-sectional study.

Methods

The present population-based cross-sectional study was conducted on an elderly population above 60 years of age in Tehran, Iran in 2019. The sampling was done using the stratified multistage random cluster sampling method. All study participants underwent a complete optometric examination and slit-lamp biomicroscopy.

Results

The prevalence of astigmatism higher than -0.50, -1.00, and -2.00 D was 83% (95% CI: 81 -84), 52 % (95% CI: 50 -54), and 19% (95% CI: 17-20), respectively. These prevalence was 79%(95% CI: 77-81), 46(95% CI: 44-49) and 14(95% CI: 13-16) in subjects without a history of ocular surgery, respectively. Based on cylinder power worse than -1.00 D, 10% (95% CI: 9-12), 20% (95% CI: 18-22), and 21% (95% CI:19-23) of study participants had with the rule, against the rule, and oblique astigmatism, respectively. According to the results of the multiple regression model, male gender, older age, low education level, pure posterior subcapsular cataract, pseudophakia, and myopia were independent factors associated with astigmatism. The prevalence of anisorule astigmatism was 57 % (95% CI: 56-59), the most common anisorule astigmatism was against the rule-oblique type with a prevalence of 36% (95% CI: 34-38).

Conclusion

The prevalence of astigmatism was high in the elderly population of Tehran. More than half of the participants in this study had anisorule astigmatism, and against the rule-oblique combination was more prevalent than other types. A posterior subcapsular cataract, a history of cataract surgery, and myopia were the associated factors of astigmatism in this study.

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References

  1. Anton A, Andrada MT, Mayo A, Portela J, Merayo J. Epidemiology of refractive errors in an adult European population: the Segovia study. Ophthalmic epidemiol. 2009;16:231–7.

    Article  PubMed  Google Scholar 

  2. GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study. Lancet Glob health. 2021;9:e144–60.

    Article  Google Scholar 

  3. Hashemi H, Fotouhi A, Yekta A, Pakzad R, Ostadimoghaddam H, Khabazkhoob M. Global and regional estimates of prevalence of refractive errors: systematic review and meta-analysis. J Curr Ophthalmol. 2018;30:3–22.

    Article  PubMed  Google Scholar 

  4. Sanfilippo PG, Yazar S, Kearns L, Sherwin JC, Hewitt AW, Mackey DA. Distribution of astigmatism as a function of age in an Australian population. Acta ophthalmol. 2015;93:e377–85.

    Article  PubMed  Google Scholar 

  5. Khoshhal F, Hashemi H, Hooshmand E, Saatchi M, Yekta A, Aghamirsalim M, et al. The prevalence of refractive errors in the Middle East: a systematic review and meta-analysis. Int ophthalmol. 2020;40:1571–86.

    Article  PubMed  Google Scholar 

  6. Day AC, Dhariwal M, Keith MS, Ender F, Perez Vives C, Miglio C, et al. Distribution of preoperative and postoperative astigmatism in a large population of patients undergoing cataract surgery in the UK. Br J Ophthalmol. 2019;103:993–1000.

    Article  PubMed  Google Scholar 

  7. Prasher P, Sandhu JS. Prevalence of corneal astigmatism before cataract surgery in Indian population. Intophthalmol. 2017;37:683–9.

    Google Scholar 

  8. Sigireddi RR, Weikert MP. How much astigmatism to treat in cataract surgery. Curr Opin Ophthalmol. 2020;31:10–4.

    Article  PubMed  Google Scholar 

  9. Cheng F, Shan L, Song W, Fan P, Zhang L, Wang X, et al. Prevalence and risk factor for refractive error in rural Chinese adults in Kailu, Inner Mongolia. Ophthalmic Physiol Opt. 2021;41:13–20.

    Article  PubMed  Google Scholar 

  10. Sawada A, Tomidokoro A, Araie M, Iwase A, Yamamoto T, Tajimi Study G. Refractive errors in an elderly Japanese population: the Tajimi study. Ophthalmology. 2008;115:363 e3-370 e3.

    Article  Google Scholar 

  11. Hashemi H, Hatef E, Fotouhi A, Mohammad K. Astigmatism and its determinants in the Tehran population: the Tehran eye study. Ophthalmic epidemiol. 2005;12:373–81.

    Article  PubMed  Google Scholar 

  12. Asharlous A, Khabazkhoob M, Yekta A, Hashemi H. Comprehensive profile of bilateral astigmatism: rule similarity and symmetry patterns of the axes in the fellow eyes. Ophthalmic Physiolopt. 2017;37:33–41.

    Article  Google Scholar 

  13. Hashemi H, Khabazkhoob M, Yekta A, Jafarzadehpur E, Emamian MH, Shariati M, et al. High prevalence of astigmatism in the 40- to 64-year-old population of Shahroud, Iran. Clin Ex Ophthalmol. 2012;40:247–54.

    Article  Google Scholar 

  14. Emamian MH, Hashemi H, Khabazkhoob M, Malihi S, Fotouhi A. Cohort profile: Shahroud schoolchildren eye cohort study (SSCECS). Int J Epidemiol. 2019;48:27-f.

    Article  Google Scholar 

  15. Mencucci R, Giordano C, Favuzza E, Gicquel JJ, Spadea L, Menchini U. Astigmatism correction with toric intraocular lenses: wavefront aberrometry and quality of life. Brjophthalmol. 2013;97:578–82.

    Google Scholar 

  16. Anderson DF, Dhariwal M, Bouchet C, Keith MS. Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review. Clinl Ophthalmol (Auckland, NZ). 2018;12:439–52.

    Article  Google Scholar 

  17. Thylefors B, Chylack LT Jr, Konyama K, Sasaki K, Sperduto R, Taylor HR, et al. A simplified cataract grading system. Ophthalmic Epidemiol. 2002;9:83–95.

    Article  CAS  PubMed  Google Scholar 

  18. Guggenheim JA, Zayats T, Prashar A, To CH. Axes of astigmatism in fellow eyes show mirror rather than direct symmetry. Ophthalmic physiol opt. 2008;28:327–33.

    Article  PubMed  Google Scholar 

  19. Cheng CY, Hsu WM, Liu JH, Tsai SY, Chou P. Refractive errors in an elderly Chinese population in Taiwan: the Shihpai Eye Study. Invest Ophthalmol Vis Sci. 2003;44:4630–8.

    Article  PubMed  Google Scholar 

  20. Hashemi H, Nabovati P, Malekifar A, Yekta A, Ostadimoghaddam H, Jafarzadehpur E, et al. Astigmatism in underserved rural areas: a population based study. Ophthalmic Physiol Opt. 2016;36:671–9.

    Article  PubMed  Google Scholar 

  21. Hashemi H, Rezvan F, Yekta AA, Hashemi M, Norouzirad R, Khabazkhoob M. The prevalence of astigmatism and its determinants in a rural population of Iran: the “Nooravaran Salamat” mobile eye clinic experience. Middle East Afr J Ophthalmol. 2014;21:175–81.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Ostadimoghaddam H, Fotouhi A, Hashemi H, Yekta A, Heravian J, Rezvan F, et al. Prevalence of the refractive errors by age and gender: the Mashhad eye study of Iran. Clin Ex Ophthalmol. 2011;39:743–51.

    Article  Google Scholar 

  23. Liang YB, Wong TY, Sun LP, Tao QS, Wang JJ, Yang XH, et al. Refractive errors in a rural Chinese adult population the Handan eye study. Ophthalmology. 2009;116:2119–27.

    Article  PubMed  Google Scholar 

  24. Gupta A, Casson RJ, Newland HS, Muecke J, Landers J, Selva D, et al. Prevalence of refractive error in rural Myanmar: the Meiktila Eye Study. Ophthalmology. 2008;115:26–32.

    Article  CAS  PubMed  Google Scholar 

  25. Wolfram C, Hohn R, Kottler U, Wild P, Blettner M, Buhren J, et al. Prevalence of refractive errors in the European adult population: the Gutenberg Health Study (GHS). Br J Ophthalmol. 2014;98:857–61.

    Article  PubMed  Google Scholar 

  26. Bourne RR, Dineen BP, Ali SM, Noorul Huq DM, Johnson GJ. Prevalence of refractive error in Bangladeshi adults: results of the National Blindness and Low Vision Survey of Bangladesh. Ophthalmology. 2004;111:1150–60.

    Article  PubMed  Google Scholar 

  27. Joseph S, Krishnan T, Ravindran RD, Maraini G, Camparini M, Chakravarthy U, et al. Prevalence and risk factors for myopia and other refractive errors in an adult population in southern India. Ophthalmic Physiol Opt. 2018;38:346–58.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Rim TH, Kim SH, Lim KH, Choi M, Kim HY, Baek SH, et al. Refractive Errors in Koreans: the Korea National Health and Nutrition Examination Survey 2008–2012. Korean J Ophthalmol. 2016;30:214–24.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Attebo K, Ivers RQ, Mitchell P. Refractive errors in an older population: the Blue Mountains Eye Study. Ophthalmology. 1999;106:1066–72.

    Article  CAS  PubMed  Google Scholar 

  30. Yekta AA, Fotouhi A, Khabazkhoob M, Hashemi H, Ostadimoghaddam H, Heravian J, et al. The prevalence of refractive errors and its determinants in the elderly population of Mashhad, Iran. Ophthalmic Epidemiol. 2009;16:198–203.

    Article  PubMed  Google Scholar 

  31. Krishnaiah S, Srinivas M, Khanna RC, Rao GN. Prevalence and risk factors for refractive errors in the South Indian adult population: the Andhra Pradesh Eye disease study. Clinophthalmol (Auckland, NZ). 2009;3:17–27.

    Google Scholar 

  32. Wong TY, Foster PJ, Hee J, Ng TP, Tielsch JM, Chew SJ, et al. Prevalence and risk factors for refractive errors in adult Chinese in Singapore. Invest Ophthalmol Vis Sci. 2000;41:2486–94.

    CAS  PubMed  Google Scholar 

  33. Nakamura Y, Nakamura Y, Higa A, Sawaguchi S, Tomidokoro A, Iwase A, et al. Refractive errors in an elderly rural Japanese population: the Kumejima study. PLoS ONE. 2018;13: e0207180.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  34. Saw SM, Chan YH, Wong WL, Shankar A, Sandar M, Aung T, et al. Prevalence and risk factors for refractive errors in the Singapore Malay Eye Survey. Ophthalmology. 2008;115:1713–9.

    Article  PubMed  Google Scholar 

  35. Varma R, Torres M, McKean-Cowdin R, Rong F, Hsu C, Jiang X, et al. Prevalence and risk factors for refractive error in adult Chinese Americans: the Chinese American Eye Study. Am J Ophthalmol. 2017;175:201–12.

    Article  PubMed  Google Scholar 

  36. Ziaei H, Katibeh M, Solaimanizad R, Hosseini S, Gilasi HR, Golbafian F, et al. Prevalence of refractive errors; the yazd eye study. Jophthal vis research. 2013;8:227–36.

    Google Scholar 

  37. Raju P, Ramesh SV, Arvind H, George R, Baskaran M, Paul PG, et al. Prevalence of refractive errors in a rural South Indian population. Invest Ophthalmol Vis Sci. 2004;45:4268–72.

    Article  PubMed  Google Scholar 

  38. Ezelum C, Razavi H, Sivasubramaniam S, Gilbert CE, Murthy GV, Entekume G, et al. Refractive error in Nigerian adults: prevalence, type, and spectacle coverage. Invest Ophthalmol Vis Sci. 2011;52:5449–56.

    Article  PubMed  Google Scholar 

  39. Saw SM, Gazzard G, Koh D, Farook M, Widjaja D, Lee J, et al. Prevalence rates of refractive errors in Sumatra, Indonesia. Invest Ophthalmol Vis Sci. 2002;43:3174–80.

    PubMed  Google Scholar 

  40. Ho JD, Liou SW, Tsai RJ, Tsai CY. Effects of aging on anterior and posterior corneal astigmatism. Cornea. 2010;29:632–7.

    Article  PubMed  Google Scholar 

  41. Leung TW, Lam AK, Deng L, Kee CS. Characteristics of astigmatism as a function of age in a Hong Kong clinical population. Optom Vis Sci. 2012;89:984–92.

    Article  PubMed  Google Scholar 

  42. Shao X, Zhou KJ, Pan AP, Cheng XY, Cai HX, Huang JH, et al. Age-related changes in corneal astigmatism. J Refract Surg. 2017;33:696–703.

    Article  PubMed  Google Scholar 

  43. Gudmundsdottir E, Jonasson F, Jonsson V, Stefansson E, Sasaki H, Sasaki K. “With the rule” astigmatism is not the rule in the elderly. Reykjavik Eye Study: a population based study of refraction and visual acuity in citizens of Reykjavik 50 years and older. Iceland-Japan Co-Working Study Groups. Acta ophthalmol Scand. 2000;78:642–6.

    Article  CAS  PubMed  Google Scholar 

  44. Collier Wakefield O, Annoh R, Nanavaty MA. Relationship between age, corneal astigmatism, and ocular dimensions with reference to astigmatism in eyes undergoing routine cataract surgery. Eye (London). 2016;30:562–9.

    Article  CAS  PubMed Central  Google Scholar 

  45. Asano K, Nomura H, Iwano M, Ando F, Niino N, Shimokata H, et al. Relationship between astigmatism and aging in middle-aged and elderly Japanese. Jpn J Ophthalmol. 2005;49:127–33.

    Article  PubMed  Google Scholar 

  46. Namba H, Sugano A, Murakami T, Utsunomiya H, Nishitsuka K, Ishizawa K, et al. Age-related changes in astigmatism and potential causes. Cornea. 2020;39(Suppl 1):S34–8.

    Article  PubMed  Google Scholar 

  47. Mori I. Effect of extraocular muscles on the aging shift in corneal astigmatism. Atarashii Ganka (J Eye). 2002;19:1345–7 (in Japanese).

    Google Scholar 

  48. Kim H, An Y, Joo CK. Gender-differences in age-related changes of corneal astigmatism in Korean cataract patients. BMC Ophthalmol. 2019;19:31.

    Article  PubMed  PubMed Central  Google Scholar 

  49. De Bernardo M, Zeppa L, Zeppa L, Cornetta P, Vitiello L, Rosa N. Biometric parameters and corneal astigmatism: differences between male and female eyes. Clin Ophthalmol (Auckland, NZ). 2020;14:571–80.

    Article  Google Scholar 

  50. Kuroda T, Fujikado T, Maeda N, Oshika T, Hirohara Y, Mihashi T. Wavefront analysis of higher-order aberrations in patients with cataract. J Cataract Refract Surg. 2002;28:438–44.

    Article  PubMed  Google Scholar 

  51. Pesudovs K, Elliott DB. Refractive error changes in cortical, nuclear, and posterior subcapsular cataracts. Br J Ophthalmol. 2003;87:964–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  52. Wong TY, Foster PJ, Johnson GJ, Seah SK. Refractive errors, axial ocular dimensions, and age-related cataracts: the Tanjong Pagar survey. Invest Ophthalmol Vis Sci. 2003;44:1479–85.

    Article  PubMed  Google Scholar 

  53. Yao K, Tang X, Ye P. Corneal astigmatism, high order aberrations, and optical quality after cataract surgery: microincision versus small incision. J Refract Surg. 2006;22:S1079–82.

    Article  PubMed  Google Scholar 

  54. Oshika T, Shimazaki J, Yoshitomi F, Oki K, Sakabe I, Matsuda S, et al. Arcuate keratotomy to treat corneal astigmatism after cataract surgery: a prospective evaluation of predictability and effectiveness. Ophthalmology. 1998;105:2012–6.

    Article  CAS  PubMed  Google Scholar 

  55. Kaye SB, Patterson A. Association between total astigmatism and myopia. J Cataract Refract Surg. 1997;23:1496–502.

    Article  CAS  PubMed  Google Scholar 

  56. Twelker JD, Miller JM, Sherrill DL, Harvey EM. Astigmatism and myopia in Tohono O’odham Native American children. Optom Vis Sci. 2013;90:1267–73.

    Article  PubMed  PubMed Central  Google Scholar 

  57. Hammond CJ, Snieder H, Gilbert CE, Spector TD. Genes and environment in refractive error: the twin eye study. Invest Ophthalmol Vis Sci. 2001;42:1232–6.

    CAS  PubMed  Google Scholar 

  58. Dirani M, Islam A, Shekar SN, Baird PN. Dominant genetic effects on corneal astigmatism: the genes in myopia (GEM) twin study. Invest Ophthalmol Vis Sci. 2008;49:1339–44.

    Article  PubMed  Google Scholar 

  59. Sheedy JE, Truong SD, Hayes JR. What are the visual benefits of eyelid squinting? Optom Vis Sci. 2003;80:740–4.

    Article  PubMed  Google Scholar 

  60. Tong L, Saw SM, Carkeet A, Chan WY, Wu HM, Tan D. Prevalence rates and epidemiological risk factors for astigmatism in Singapore school children. Optom Vis Sci. 2002;79:606–13.

    Article  PubMed  Google Scholar 

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Funding

This project was supported by National Institute for Medical Research Development (NIMAD) affiliated with the Iranian Ministry of Health and Medical Education (grant code: 963660).

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Correspondence to Mehdi Khabazkhoob.

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Conflicts of interest

H. Hashemi, None; A. Asharlous, None; A. Yekta, None; M. Aghamirsalim, None; P. Nabovati, None; M. M. Sadoughi, None; M. Khabazkhoob, None.

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Corresponding Author: Mehdi Khabazkhoob

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Hashemi, H., Asharlous, A., Yekta, A. et al. Astigmatism profile in the elderly population: Tehran Geriatric Eye Study. Jpn J Ophthalmol 66, 461–473 (2022). https://doi.org/10.1007/s10384-022-00936-x

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  • DOI: https://doi.org/10.1007/s10384-022-00936-x

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